Journal
BIOMEDICAL OPTICS EXPRESS
Volume 7, Issue 12, Pages 4847-4858Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.7.004847
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Funding
- National Research Foundation of Korea [2010-0017465, 2012R1A2A2A04046108]
- Ministry of Health and Welfare of Korea [HI15C0001]
- National Institutes of Health [P41 EB015903]
- National Research Foundation of Korea [2012R1A2A2A04046108, 2010-0017465] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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While high-speed intracoronary optical coherence tomography (OCT) provides three-dimensional (3D) visualization of coronary arteries in vivo, imaging speeds remain insufficient to avoid motion artifacts induced by heartbeat, limiting the clinical utility of OCT. In this paper, we demonstrate development of a high-speed intracoronary OCT system (frame rate: 500 frames/s, pullback speed: 100 mm/s) along with prospective electrocardiogram (ECG) triggering technology, which enabled volumetric imaging of long coronary segments within a single cardiac cycle (70 mm pullback in 0.7 s) with minimal cardiac motion artifact. This technology permitted detailed visualization of 3D architecture of the coronary arterial wall of a swine in vivo and fine structure of the implanted stent. (C) 2016 Optical Society of America
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