A rapid microwave assisted synthesis of 1-(6-chloro-2-methyl-4-phenylquinolin-3-yl)-3-(aryl)prop-2-en-1-ones and their anti bacterial and anti fungal evaluation

The 1-(6-chloro-2-methyl-4-phenylquinolin-3-yl)-3-(aryl) prop-2-en-1-ones were synthesized by microwave assisted synthesis, the antimicrobial activities of synthesized compounds were screened against Gram negative organisms such as Escherichia coli (ATCC 25922), Bacillus subtilis (ATCC 117788), Salmonella typhi (ATCC 25264), Gram positive Staphylococcus aureus (ATCC 700699) and fungal organisms such as Aspergillus flavus, Aspergillus fumigatus and Candida utilius. (C) 2011 Production and hosting by Elsevier B.V. on behalf of King Saud University.