EZH1 and EZH2 promote skeletal growth by repressing inhibitors of chondrocyte proliferation and hypertrophy

Weaver Syndrome-Associated EZH2 Protein Variants Show Impaired Histone Methyltransferase Function In Vitro

(2016) Ana S.A. Cohen et al.   HUMAN MUTATION

Polycomb repressive complex 2 regulates skeletal growth by suppressing Wnt and TGF-β signalling

(2016) Fatemeh Mirzamohammadi et al.   Nature Communications

The methyltransferases enhancer of zeste homolog (EZH) 1 and EZH2 control hepatocyte homeostasis and regeneration

(2015) Woo Kyun Bae et al.   FASEB JOURNAL

Mice Deficient in AKAP13 (BRX ) Are Osteoporotic and Have Impaired Osteogenesis

(2015) Hisashi Koide et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A novel mutation in EED associated with overgrowth

(2015) Ana S A Cohen et al.   JOURNAL OF HUMAN GENETICS

JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice

(2015) Feng Zhang et al.   Journal of Molecular Cell Biology

Germline mutations in the oncogene EZH2 cause Weaver syndrome and increased human height

(2015) Katrina Tatton-Brown et al.   Oncotarget

Mutations inSETD2cause a novel overgrowth condition

(2014) Armelle Luscan et al.   JOURNAL OF MEDICAL GENETICS

EZH2 Represses Target Genes through H3K27-Dependent and H3K27-Independent Mechanisms in Hepatocellular Carcinoma

(2014) Shu-Bin Gao et al.   MOLECULAR CANCER RESEARCH

Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability

(2014) Katrina Tatton-Brown et al.   NATURE GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Spatial regulation of gene expression during growth of articular cartilage in juvenile mice

(2014) Julian C. Lui et al.   PEDIATRIC RESEARCH

Multiple phases of chondrocyte enlargement underlie differences in skeletal proportions

(2013) Kimberly L. Cooper et al.   NATURE

Evidence that Igf2 down-regulation in postnatal tissues and up-regulation in malignancies is driven by transcription factor E2f3

(2013) J. C. Lui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesizing genome-wide association studies and expression microarray reveals novel genes that act in the human growth plate to modulate height

(2012) Julian C. Lui et al.   HUMAN MOLECULAR GENETICS

Ezh2 maintains a key phase of muscle satellite cell expansion but does not regulate terminal differentiation

(2012) S. Woodhouse et al.   JOURNAL OF CELL SCIENCE

The histone H3K27 methylation mark regulates intestinal epithelial cell density-dependent proliferation and the inflammatory response

(2012) Naomie Turgeon et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Mutations in EZH2 Cause Weaver Syndrome

(2011) William T. Gibson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair

(2011) E. Ezhkova et al.   GENES & DEVELOPMENT

Spatial and temporal regulation of gene expression in the mammalian growth plate

(2010) Julian C.K. Lui et al.   BONE

Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth

(2010) Julian C. Lui et al.   FASEB JOURNAL

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

(2010) C. J. Sneeringer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells

(2009) Manjari Dimri et al.   CARCINOGENESIS

Polycomb protein Ezh2 regulates pancreatic  -cell Ink4a/Arf expression and regeneration in diabetes mellitus

(2009) H. Chen et al.   GENES & DEVELOPMENT

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells

(2009) F. Sun et al.   MOLECULAR CANCER THERAPEUTICS

EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence

(2009) Sima Kheradmand Kia et al.   Epigenetics & Chromatin

Ezh1 and Ezh2 Maintain Repressive Chromatin through Different Mechanisms

(2008) Raphael Margueron et al.   MOLECULAR CELL

EZH1 Mediates Methylation on Histone H3 Lysine 27 and Complements EZH2 in Maintaining Stem Cell Identity and Executing Pluripotency

(2008) Xiaohua Shen et al.   MOLECULAR CELL