Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin–microtubule interface

A flipped ion pair at the dynein–microtubule interface is critical for dynein motility and ATPase activation

(2015) Seiichi Uchimura et al.   JOURNAL OF CELL BIOLOGY

The wide spectrum of tubulinopathies: what are the key features for the diagnosis?

(2014) Nadia Bahi-Buisson et al.   BRAIN

Human CFEOM1 Mutations Attenuate KIF21A Autoinhibition and Cause Oculomotor Axon Stalling

(2014) Long Cheng et al.   NEURON

The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement

(2014) Luyan Cao et al.   Nature Communications

Microtubule dynamics in axon guidance

(2014) Guofa Liu et al.   Neuroscience Bulletin

High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

(2014) Zhiguo Shang et al.   eLife

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

(2014) Joseph Atherton et al.   eLife

The multiple roles of histidine in protein interactions

(2013) Si-Ming Liao et al.   Chemistry Central Journal

Initial Neurite Outgrowth in Drosophila Neurons Is Driven by Kinesin-Powered Microtubule Sliding

(2013) Wen Lu et al.   CURRENT BIOLOGY

CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor

(2013) Babet van der Vaart et al.   DEVELOPMENTAL CELL

β-Tubulin mutations that cause severe neuropathies disrupt axonal transport

(2013) Shinsuke Niwa et al.   EMBO JOURNAL

Overexpression, purification, and functional analysis of recombinant human tubulin dimer

(2013) Itsushi Minoura et al.   FEBS LETTERS

Beta tubulin isoforms are not interchangeable for rescuing impaired radial migration due to Tubb3 knockdown

(2013) Y. Saillour et al.   HUMAN MOLECULAR GENETICS

Structure of a kinesin–tubulin complex and implications for kinesin motility

(2013) Benoît Gigant et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

All-Atom Structural Investigation of Kinesin–Microtubule Complex Constrained by High-Quality Cryo-Electron-Microscopy Maps

(2012) Minghui Li et al.   BIOCHEMISTRY

Mutations in the β-Tubulin Gene TUBB5 Cause Microcephaly with Structural Brain Abnormalities

(2012) Martin Breuss et al.   Cell Reports

Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes

(2011) M. H. Longair et al.   BIOINFORMATICS

Phenotypic spectrum of the tubulin-related disorders and functional implications of disease-causing mutations

(2011) Max A Tischfield et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Electrostatically Biased Binding of Kinesin to Microtubules

(2011) Barry J. Grant et al.   PLOS BIOLOGY

MicroTUB(B3)ules and Brain Development

(2010) Karun K. Singh et al.   CELL

Human TUBB3 Mutations Perturb Microtubule Dynamics, Kinesin Interactions, and Axon Guidance

(2010) Max A. Tischfield et al.   CELL

Key residues on microtubule responsible for activation of kinesin ATPase

(2010) Seiichi Uchimura et al.   EMBO JOURNAL

Mutations in the neuronal β-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects

(2010) Karine Poirier et al.   HUMAN MOLECULAR GENETICS

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

Brownian search-and-catch mechanism for myosin-VI steps

(2009) Mitsuhiro Iwaki et al.   Nature Chemical Biology

Mutations in the β-tubulin gene TUBB2B result in asymmetrical polymicrogyria

(2009) Xavier Hubert Jaglin et al.   NATURE GENETICS

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

(2009) Yoshiyuki Konishi et al.   NATURE NEUROSCIENCE

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Electrostatic rate enhancement and transient complex of protein–protein association

(2007) Ramzi Alsallaq et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS