- Home
- Publications
- Publication Search
- Publication Details
Title
Contracting CAG/CTG repeats using the CRISPR-Cas9 nickase
Authors
Keywords
-
Journal
Nature Communications
Volume 7, Issue -, Pages 13272
Publisher
Springer Nature
Online
2016-11-09
DOI
10.1038/ncomms13272
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Disease-associated repeat instability and mismatch repair
- (2016) Monika H.M. Schmidt et al. DNA REPAIR
- Environmental Stress Induces Trinucleotide Repeat Mutagenesis in Human Cells by Alt-Nonhomologous End Joining Repair
- (2016) Nimrat Chatterjee et al. JOURNAL OF MOLECULAR BIOLOGY
- Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability
- (2015) Xiaofeng A. Su et al. GENES & DEVELOPMENT
- Expanding the Biologist’s Toolkit with CRISPR-Cas9
- (2015) Samuel H. Sternberg et al. MOLECULAR CELL
- Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia
- (2015) Yanjie Li et al. MOLECULAR THERAPY
- Shortening trinucleotide repeats using highly specific endonucleases: a possible approach to gene therapy?
- (2015) Guy-Franck Richard TRENDS IN GENETICS
- Large expansion of CTG•CAG repeats is exacerbated by MutSβ in human cells
- (2015) Rie Nakatani et al. Scientific Reports
- Short Inverted Repeats Are Hotspots for Genetic Instability: Relevance to Cancer Genomes
- (2015) Steve Lu et al. Cell Reports
- Reversion of FMR1 Methylation and Silencing by Editing the Triplet Repeats in Fragile X iPSC-Derived Neurons
- (2015) Chul-Yong Park et al. Cell Reports
- Suppression of Somatic Expansion Delays the Onset of Pathophysiology in a Mouse Model of Huntington’s Disease
- (2015) Helen Budworth et al. PLoS Genetics
- Trinucleotide expansion in disease: why is there a length threshold?
- (2014) Do-Yup Lee et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Impact of alternative DNA structures on DNA damage, DNA repair, and genetic instability
- (2014) Guliang Wang et al. DNA REPAIR
- NuA4 Initiates Dynamic Histone H4 Acetylation to Promote High-Fidelity Sister Chromatid Recombination at Postreplication Gaps
- (2014) Nealia C.M. House et al. MOLECULAR CELL
- Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
- (2014) Cem Kuscu et al. NATURE BIOTECHNOLOGY
- GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
- (2014) Shengdar Q Tsai et al. NATURE BIOTECHNOLOGY
- Highly Specific Contractions of a Single CAG/CTG Trinucleotide Repeat by TALEN in Yeast
- (2014) Guy-Franck Richard et al. PLoS One
- GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells
- (2014) Beatriz A. Santillan et al. PLoS One
- Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair
- (2014) L. Davis et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue specificity in DNA repair: lessons from trinucleotide repeat instability
- (2014) Vincent Dion TRENDS IN GENETICS
- PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks
- (2013) Michael J. Metzger et al. DNA REPAIR
- Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases
- (2013) S. W. Cho et al. GENOME RESEARCH
- Length-dependent CTG{middle dot}CAG triplet-repeat expansion in myotonic dystrophy patient-derived induced pluripotent stem cells
- (2013) J. Du et al. HUMAN MOLECULAR GENETICS
- RNA-Guided Human Genome Engineering via Cas9
- (2013) P. Mali et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- DNA Damage Sensing by the ATM and ATR Kinases
- (2013) A. Marechal et al. Cold Spring Harbor Perspectives in Biology
- Detection of Slipped-DNAs at the Trinucleotide Repeats of the Myotonic Dystrophy Type I Disease Locus in Patient Tissues
- (2013) Michelle M. Axford et al. PLoS Genetics
- The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy
- (2012) Remko Prevo et al. CANCER BIOLOGY & THERAPY
- Genetic Correction of Huntington's Disease Phenotypes in Induced Pluripotent Stem Cells
- (2012) Mahru C. An et al. Cell Stem Cell
- Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
- (2012) L. Mollersen et al. HUMAN MOLECULAR GENETICS
- Nucleotide Excision Repair, Mismatch Repair, and R-Loops Modulate Convergent Transcription-Induced Cell Death and Repeat Instability
- (2012) Yunfu Lin et al. PLoS One
- A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
- (2012) M. Jinek et al. SCIENCE
- Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1
- (2011) Leroy Hubert et al. HUMAN MOLECULAR GENETICS
- Topoisomerase 1 and Single-Strand Break Repair Modulate Transcription-Induced CAG Repeat Contraction in Human Cells
- (2011) L. Hubert et al. MOLECULAR AND CELLULAR BIOLOGY
- Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation
- (2010) Anna Seriola et al. HUMAN MOLECULAR GENETICS
- Replication-dependent instability at (CTG)•(CAG) repeat hairpins in human cells
- (2010) Guoqi Liu et al. Nature Chemical Biology
- Mechanisms of trinucleotide repeat instability during human development
- (2010) Cynthia T. McMurray NATURE REVIEWS GENETICS
- Repeat instability as the basis for human diseases and as a potential target for therapy
- (2010) Arturo López Castel et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Double-Strand Break Repair Pathways Protect against CAG/CTG Repeat Expansions, Contractions and Repeat-Mediated Chromosomal Fragility in Saccharomyces cerevisiae
- (2009) R. Sundararajan et al. GENETICS
- Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
- (2009) S. E. Golding et al. MOLECULAR CANCER THERAPEUTICS
- Incision-dependent and error-free repair of (CAG) n /(CTG) n hairpins in human cell extracts
- (2009) Caixia Hou et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ATM and ATR protect the genome against two different types of tandem repeat instability in Fragile X premutation mice
- (2009) A. Entezam et al. NUCLEIC ACIDS RESEARCH
- Zinc-finger directed double-strand breaks within CAG repeat tracts promote repeat instability in human cells
- (2009) D. Mittelman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- XRCC1 and DNA polymerase β in cellular protection against cytotoxic DNA single-strand breaks
- (2008) Julie K Horton et al. CELL RESEARCH
- Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline
- (2008) Vincent Dion et al. HUMAN MOLECULAR GENETICS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation