Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors

Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3

(2016) Elham Jalalvand et al.   Nature Communications

Piezo2 is the principal mechanotransduction channel for proprioception

(2015) Seung-Hyun Woo et al.   NATURE NEUROSCIENCE

Genetic exploration of the role of acid-sensing ion channels

(2015) Shing-Hong Lin et al.   NEUROPHARMACOLOGY

Piezo2 is the major transducer of mechanical forces for touch sensation in mice

(2014) Sanjeev S. Ranade et al.   NATURE

Tuning Piezo ion channels to detect molecular-scale movements relevant for fine touch

(2014) Kate Poole et al.   Nature Communications

Transient Receptor Potential Channels and Mechanosensation

(2013) Niels Eijkelkamp et al.   Annual Review of Neuroscience

Neurosensory mechanotransduction through acid-sensing ion channels

(2013) Chih-Cheng Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Stomatin-domain protein interactions with acid-sensing ion channels modulate nociceptor mechanosensitivity

(2013) Rabih A. Moshourab et al.   JOURNAL OF PHYSIOLOGY-LONDON

Subunit-specific inhibition of acid sensing ion channels by stomatin-like protein 1

(2013) Alexey Kozlenkov et al.   JOURNAL OF PHYSIOLOGY-LONDON

Etv1 Inactivation Reveals Proprioceptor Subclasses that Reflect the Level of NT3 Expression in Muscle Targets

(2013) Joriene C. de Nooij et al.   NEURON

A role for Piezo2 in EPAC1-dependent mechanical allodynia

(2013) N Eijkelkamp et al.   Nature Communications

Gating the mechanical channel Piezo1

(2012) Philip A. Gottlieb et al.   Channels

Acid-sensing ion channels (ASICs) in mouse skeletal muscle afferents are heteromers composed of ASIC1a, ASIC2, and ASIC3 subunits

(2012) Mamta Gautam et al.   FASEB JOURNAL

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

Asic3 is a neuronal mechanosensor for pressure-induced vasodilation that protects against pressure ulcers

(2012) Bérengère Fromy et al.   NATURE MEDICINE

Targeting ASIC3 for pain, anxiety, and insulin resistance

(2012) Wei-Li Wu et al.   PHARMACOLOGY & THERAPEUTICS

Simultaneous Disruption of Mouse ASIC1a, ASIC2 and ASIC3 Genes Enhances Cutaneous Mechanosensitivity

(2012) Sinyoung Kang et al.   PLoS One

Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions

(2012) A. Delaunay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the Acid-Sensing Ion Channel 3 in Blood Volume Control

(2011) Cheng-Han Lee et al.   CIRCULATION JOURNAL

Laminin-332 coordinates mechanotransduction and growth cone bifurcation in sensory neurons

(2011) Li-Yang Chiang et al.   NATURE NEUROSCIENCE

Recording of mechanosensitive currents using piezoelectrically driven mechanostimulator

(2011) Jizhe Hao et al.   Nature Protocols

Molecular mechanisms of mechanotransduction in mammalian sensory neurons

(2011) Patrick Delmas et al.   NATURE REVIEWS NEUROSCIENCE

DEG/ENaC but Not TRP Channels Are the Major Mechanoelectrical Transduction Channels in a C. elegans Nociceptor

(2011) Shana L. Geffeney et al.   NEURON

An antinociceptive role for substance P in acid-induced chronic muscle pain

(2011) C.-C. J. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pickpocket Is a DEG/ENaC Protein Required for Mechanical Nociception in Drosophila Larvae

(2010) Lixian Zhong et al.   CURRENT BIOLOGY

Evidence for a protein tether involved in somatic touch

(2010) Jing Hu et al.   EMBO JOURNAL

Probing localized neural mechanotransduction through surface-modified elastomeric matrices and electrophysiology

(2010) Chao-Min Cheng et al.   Nature Protocols

Sensing Muscle Ischemia: Coincident Detection of Acid and ATP via Interplay of Two Ion Channels

(2010) William T. Birdsong et al.   NEURON

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development

(2009) Stefan G Lechner et al.   EMBO JOURNAL

Acid-sensing ion channels in neurones of the rat suprachiasmatic nucleus

(2009) Chun-Hao Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Amiloride-sensitive channels are a major contributor to mechanotransduction in mammalian muscle spindles

(2009) Anna Simon et al.   JOURNAL OF PHYSIOLOGY-LONDON

Understanding Sensory Nerve Mechanotransduction through Localized Elastomeric Matrix Control

(2009) Yi-Wen Lin et al.   PLoS One

Enhanced muscle fatigue occurs in male but not female ASIC3−/− mice

(2008) Lynn A. Burnes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Abnormal Muscle Spindle Innervation and Large-Fiber Neuropathy in Diabetic Mice

(2008) K. A. Muller et al.   DIABETES

ASIC3, a sensor of acidic and primary inflammatory pain

(2008) Emmanuel Deval et al.   EMBO JOURNAL

Neurosensory mechanotransduction

(2008) Martin Chalfie   NATURE REVIEWS MOLECULAR CELL BIOLOGY