Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy

VISA - Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing

(2015) Jonah D. Hocum et al.   BMC BIOINFORMATICS

Umbilical cord blood graft engineering: challenges and opportunities

(2015) P A Thompson et al.   BONE MARROW TRANSPLANTATION

Gene therapy for monogenic disorders of the bone marrow

(2015) Sujal Ghosh et al.   BRITISH JOURNAL OF HAEMATOLOGY

Towards a commercial process for the manufacture of genetically modified T cells for therapy

(2015) A D Kaiser et al.   CANCER GENE THERAPY

Automated CD34+ cell isolation of peripheral blood stem cell apheresis product

(2015) Gabriele Spohn et al.   CYTOTHERAPY

Red blood cell depletion from bone marrow and peripheral blood buffy coat: a comparison of two new and three established technologies

(2015) Nadine Sorg et al.   TRANSFUSION

Gene Therapy Studies in a Canine Model of X-Linked Severe Combined Immunodeficiency

(2015) Peter J. Felsburg et al.   Human Gene Therapy Clinical Development

Intravenous injection of a foamy virus vector to correct canine SCID-X1

(2014) C. R. Burtner et al.   BLOOD

Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients

(2014) Jennifer E. Adair et al.   JOURNAL OF CLINICAL INVESTIGATION

Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

(2014) I. Fares et al.   SCIENCE

Lentiviral vectors: basic to translational

(2012) Toshie Sakuma et al.   BIOCHEMICAL JOURNAL

A novel lentiviral vector targets gene transfer into human hematopoietic stem cells in marrow from patients with bone marrow failure syndrome and in vivo in humanized mice

(2011) C. Frecha et al.   BLOOD

Engineered T-cell therapy shows efficacy in blood cancer

(2011) Simon Frantz   NATURE BIOTECHNOLOGY

Ex vivo gene transfer and correction for cell-based therapies

(2011) Luigi Naldini   NATURE REVIEWS GENETICS

Large animal models of hematopoietic stem cell gene therapy

(2010) G D Trobridge et al.   GENE THERAPY

Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector

(2010) P S Becker et al.   GENE THERAPY

Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates

(2010) Brian C. Beard et al.   JOURNAL OF CLINICAL INVESTIGATION

Development of Lentiviral Vectors with Optimized Transcriptional Activity for the Gene Therapy of Patients with Fanconi Anemia

(2009) África González-Murillo et al.   HUMAN GENE THERAPY

Reciprocal Relationship between O6-Methylguanine-DNA Methyltransferase P140K Expression Level and Chemoprotection of Hematopoietic Stem Cells

(2008) M. D. Milsom et al.   CANCER RESEARCH