LATS-YAP/TAZ controls lineage specification by regulating TGFβ signaling and Hnf4α expression during liver development

Cellular Homeostasis and Repair in the Mammalian Liver

(2015) Ben Z. Stanger   Annual Review of Physiology

Brahma regulates the Hippo pathway activity through forming complex with Yki–Sd and regulating the transcription of Crumbs

(2015) Ye Zhu et al.   CELLULAR SIGNALLING

Yes-associated protein in the liver: Regulation of hepatic development, repair, cell fate determination and tumorigenesis

(2015) Quy Nguyen et al.   DIGESTIVE AND LIVER DISEASE

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

(2015) Inês Cebola et al.   NATURE CELL BIOLOGY

YAP and TAZ: a nexus for Hippo signaling and beyond

(2015) Carsten Gram Hansen et al.   TRENDS IN CELL BIOLOGY

Control of Organ Growth by Patterning and Hippo Signaling inDrosophila

(2015) Kenneth D. Irvine et al.   Cold Spring Harbor Perspectives in Biology

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression

(2015) Julien Fitamant et al.   Cell Reports

Hippo Pathway Activity Influences Liver Cell Fate

(2014) Dean Yimlamai et al.   CELL

Monitoring fibrogenic progression in the liver

(2014) Olav A. Gressner et al.   CLINICA CHIMICA ACTA

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment

(2014) A. Seth et al.   DEVELOPMENT

The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease

(2014) X. Varelas   DEVELOPMENT

Organ Size Control Is Dominant over Rb Family Inactivation to Restrict Proliferation In Vivo

(2014) Ursula Ehmer et al.   Cell Reports

Hippo Signaling Influences HNF4A and FOXA2 Enhancer Switching during Hepatocyte Differentiation

(2014) Olivia Alder et al.   Cell Reports

Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues

(2013) Jiang Zhu et al.   CELL

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

(2013) Alex S. Nord et al.   CELL

CCAAT/enhancer binding protein-mediated regulation of TGF  receptor 2 expression determines the hepatoblast fate decision

(2013) K. Takayama et al.   DEVELOPMENT

cAMP/PKA signalling reinforces the LATS–YAP pathway to fully suppress YAP in response to actin cytoskeletal changes

(2013) Minchul Kim et al.   EMBO JOURNAL

Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

(2013) Tao Gao et al.   GASTROENTEROLOGY

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

(2013) Darjus Felix Tschaharganeh et al.   GASTROENTEROLOGY

Links Between Hepatic Fibrosis, Ductular Reaction, and Progenitor Cell Expansion

(2013) Michael J. Williams et al.   GASTROENTEROLOGY

Differentiation of progenitors in the liver: a matter of local choice

(2013) Luke Boulter et al.   JOURNAL OF CLINICAL INVESTIGATION

Underlying potential: cellular and molecular determinants of adult liver repair

(2013) Anna Mae Diehl et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer stem cells in the development of liver cancer

(2013) Taro Yamashita et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice

(2013) Romina Fiorotto et al.   JOURNAL OF HEPATOLOGY

Stromal–epithelial crosstalk regulates kidney progenitor cell differentiation

(2013) Amrita Das et al.   NATURE CELL BIOLOGY

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

(2013) Randy Johnson et al.   NATURE REVIEWS DRUG DISCOVERY

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis

(2013) C. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells

(2013) Tobias A. Beyer et al.   Cell Reports

Yes-associated protein regulates the hepatic response after bile duct ligation

(2012) Haibo Bai et al.   HEPATOLOGY

LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression

(2012) Tatsuyuki Chiyoda et al.   JOURNAL OF CELL BIOLOGY

Embryonic Ductal Plate Cells Give Rise to Cholangiocytes, Periportal Hepatocytes, and Adult Liver Progenitor Cells

(2011) Rodolphe Carpentier et al.   GASTROENTEROLOGY

Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras

(2011) David Matallanas et al.   MOLECULAR CELL

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

(2011) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome

(2010) J. J. Hofmann et al.   DEVELOPMENT

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1

(2010) Y. Aylon et al.   GENES & DEVELOPMENT

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP

(2010) A. M. Vigneron et al.   GENES & DEVELOPMENT

Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver

(2010) S. Benhamouche et al.   GENES & DEVELOPMENT

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

(2010) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

(2010) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis

(2010) K.-P. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Intrahepatic Bile Ducts Develop According to a New Mode of Tubulogenesis Regulated by the Transcription Factor SOX9

(2009) Aline Antoniou et al.   GASTROENTEROLOGY

Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice

(2009) Jan S. Tchorz et al.   HEPATOLOGY

Crucial Role for Mst1 and Mst2 Kinases in Early Embryonic Development of the Mouse

(2009) S. Oh et al.   MOLECULAR AND CELLULAR BIOLOGY

Embryology of Extra- and Intrahepatic Bile Ducts, the Ductal plate

(2008) T. Roskams et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

A crucial role of WW45 in developing epithelial tissues in the mouse

(2008) Joo-Hyeon Lee et al.   EMBO JOURNAL