Clinical development of TargomiRs, a miRNA mimic-based treatment for patients with recurrent thoracic cancer

A Significant Metabolic and Radiological Response after a Novel Targeted MicroRNA-based Treatment Approach in Malignant Pleural Mesothelioma

(2015) Steven C. Kao et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

First in human nanotechnology doxorubicin delivery system to target epidermal growth factor receptors in recurrent glioblastoma

(2015) James R. Whittle et al.   JOURNAL OF CLINICAL NEUROSCIENCE

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

Loss of miR-223 and JNK Signaling Contribute to Elevated Stathmin in Malignant Pleural Mesothelioma

(2015) K. A. Birnie et al.   MOLECULAR CANCER RESEARCH

Abstract C43: Safety, tolerability, and clinical activity of MRX34, the first-in-class liposomal miR-34 mimic, in patients with advanced solid tumors

(2015) Muhammad Shaalan Beg et al.   MOLECULAR CANCER THERAPEUTICS

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non–Small-Cell Lung Cancer

(2015) Julie Brahmer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer

(2015) Hossein Borghaei et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-193a-3p is a potential tumor suppressor in malignant pleural mesothelioma

(2015) Marissa Williams et al.   Oncotarget

PDL1 Regulation by p53 via miR-34

(2015) Maria Angelica Cortez et al.   JNCI-Journal of the National Cancer Institute

A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells

(2015) Benjamin J. Solomon et al.   PLoS One

Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

(2014) Maria Angelica Cortez et al.   MOLECULAR THERAPY

A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

(2014) A L Kasinski et al.   ONCOGENE

In-Depth Analysis Shows Synergy between Erlotinib and miR-34a

(2014) Jane Zhao et al.   PLoS One

Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy

(2014) Bianca C. Bernardo et al.   PLoS One

Therapeutic Use of MicroRNAs in Lung Cancer

(2014) Orazio Fortunato et al.   Biomed Research International

Restoring expression of miR-16: a novel approach to therapy for malignant pleural mesothelioma

(2013) G. Reid et al.   ANNALS OF ONCOLOGY

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer

(2013) Yun Wu et al.   Molecular Therapy-Nucleic Acids

Increased Circulating miR-625-3p: A Potential Biomarker for Patients With Malignant Pleural Mesothelioma

(2012) Michaela B. Kirschner et al.   Journal of Thoracic Oncology

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34 – a microRNA replacement therapy is headed to the clinic

(2012) Andreas G. Bader   Frontiers in Genetics

MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma

(2011) A. F. Ibrahim et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice

(2011) Phong Trang et al.   MOLECULAR THERAPY

microRNA Replacement Therapy for Cancer

(2011) Jon C. Henry et al.   PHARMACEUTICAL RESEARCH

Role of anti-oncomirs miR-143 and -145 in human colorectal tumors

(2010) Y Akao et al.   CANCER GENE THERAPY

Development of a Lung Cancer Therapeutic Based on the Tumor Suppressor MicroRNA-34

(2010) J. F. Wiggins et al.   CANCER RESEARCH

Thelet-7microRNA reduces tumor growth in mouse models of lung cancer

(2010) Aurora Esquela-Kerscher et al.   CELL CYCLE

The miR-15/107 Group of MicroRNA Genes: Evolutionary Biology, Cellular Functions, and Roles in Human Diseases

(2010) John R. Finnerty et al.   JOURNAL OF MOLECULAR BIOLOGY

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer

(2009) Nora Bandi et al.   CANCER RESEARCH

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

(2009) Fumitaka Takeshita et al.   MOLECULAR THERAPY

Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug

(2009) Jennifer A MacDiarmid et al.   NATURE BIOTECHNOLOGY

Regression of murine lung tumors by the let-7 microRNA

(2009) P Trang et al.   ONCOGENE

MicroRNAs in Cancer

(2008) Yong Sun Lee et al.   Annual Review of Pathology-Mechanisms of Disease

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE