Epigenetic regulation of axonal regenerative capacity

Differential expression of HDACs and KATs in high and low regeneration capacity neurons during spinal cord regeneration

(2016) Jie Chen et al.   EXPERIMENTAL NEUROLOGY

A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program

(2016) Vijayendran Chandran et al.   NEURON

MicroRNA-210 promotes sensory axon regeneration of adult mice in vivo and in vitro

(2016) Yi-Wen Hu et al.   NEUROSCIENCE LETTERS

MicroRNA-30b promotes axon outgrowth of retinal ganglion cells by inhibiting Semaphorin3A expression

(2015) F. Han et al.   BRAIN RESEARCH

MiR-133b Promotes Neurite Outgrowth by Targeting RhoA Expression

(2015) Xiao Cheng Lu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Filamin A Is Required in Injured Axons for HDAC5 Activity and Axon Regeneration

(2015) Yongcheol Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic Regulation of Schwann Cell Enhancers after Peripheral Nerve Injury

(2015) Holly A. Hung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor

(2015) Shiying Li et al.   MOLECULAR THERAPY

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers

(2015) Isaac B Hilton et al.   NATURE BIOTECHNOLOGY

Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair

(2015) Huimei Yu et al.   NATURE NEUROSCIENCE

MicroRNA-26a supports mammalian axon regeneration in vivo by suppressing GSK3β expression

(2015) J-J Jiang et al.   Cell Death & Disease

TET3 Is Recruited by REST for Context-Specific Hydroxymethylation and Induction of Gene Expression

(2015) Arshan Perera et al.   Cell Reports

Understanding the relationship between DNA methylation and histone lysine methylation

(2014) Nathan R. Rose et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

HDAC signaling in neuronal development and axon regeneration

(2014) Yongcheol Cho et al.   CURRENT OPINION IN NEUROBIOLOGY

Cell intrinsic control of axon regeneration

(2014) F. M. Mar et al.   EMBO REPORTS

Critical Role of Tet3 in Neural Progenitor Cell Maintenance and Terminal Differentiation

(2014) Ting Li et al.   MOLECULAR NEUROBIOLOGY

Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury

(2014) Heather M Schmitt et al.   Molecular Neurodegeneration

Decoding neural transcriptomes and epigenomes via high-throughput sequencing

(2014) Jaehoon Shin et al.   NATURE NEUROSCIENCE

Therapeutic targeting of microRNAs: current status and future challenges

(2014) Zhonghan Li et al.   NATURE REVIEWS DRUG DISCOVERY

Gene expression regulation mediated through reversible m6A RNA methylation

(2014) Ye Fu et al.   NATURE REVIEWS GENETICS

S-adenosylmethionine Levels Regulate the Schwann Cell DNA Methylome

(2014) Marta Varela-Rey et al.   NEURON

Diminished Schwann Cell Repair Responses Underlie Age-Associated Impaired Axonal Regeneration

(2014) Michio W. Painter et al.   NEURON

Expression of DNA methyltransferases in adult dorsal root ganglia is cell-type specific and up regulated in a rodent model of neuropathic pain

(2014) Sarah L. Pollema-Mays et al.   Frontiers in Cellular Neuroscience

PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system

(2014) Radhika Puttagunta et al.   Nature Communications

Injury-Induced HDAC5 Nuclear Export Is Essential for Axon Regeneration

(2013) Yongcheol Cho et al.   CELL

Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

(2013) Run-Rui Zhang et al.   Cell Stem Cell

MicroRNA-210 overexpression induces angiogenesis and neurogenesis in the normal adult mouse brain

(2013) L Zeng et al.   GENE THERAPY

MicroRNA-138 and SIRT1 form a mutual negative feedback loop to regulate mammalian axon regeneration

(2013) C.-M. Liu et al.   GENES & DEVELOPMENT

Epigenetic Regulation of Sensory Axon Regeneration after Spinal Cord Injury

(2013) M. J. Finelli et al.   JOURNAL OF NEUROSCIENCE

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

(2013) Junjie U Guo et al.   NATURE NEUROSCIENCE

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

(2013) Andrii Rudenko et al.   NEURON

DNA Modifications and Neurological Disorders

(2013) Yi-Lan Weng et al.   Neurotherapeutics

Epigenetic Regulation of Axon Outgrowth and Regeneration in CNS Injury: The First Steps Forward

(2013) Ricco Lindner et al.   Neurotherapeutics

Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve

(2013) V Pernet et al.   Cell Death & Disease

Dynamics of 5-Hydroxymethylcytosine and Chromatin Marks in Mammalian Neurogenesis

(2013) Maria A. Hahn et al.   Cell Reports

MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist Kremen1

(2013) Di Wu et al.   Frontiers in Molecular Neuroscience

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

(2012) Yufei Xu et al.   CELL

HDAC5 is a novel injury-regulated tubulin deacetylase controlling axon regeneration

(2012) Yongcheol Cho et al.   EMBO JOURNAL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

The Role of Histone Acetylation in Memory Formation and Cognitive Impairments

(2012) Lucia Peixoto et al.   NEUROPSYCHOPHARMACOLOGY

microRNA-222 Targeting PTEN Promotes Neurite Outgrowth from Adult Dorsal Root Ganglion Neurons following Sciatic Nerve Transection

(2012) Songlin Zhou et al.   PLoS One

Kruppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract

(2012) M. G. Blackmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs in neuronal function and dysfunction

(2012) Heh-In Im et al.   TRENDS IN NEUROSCIENCES

The histone acetyltransferase p300 promotes intrinsic axonal regeneration

(2011) Perrine Gaub et al.   BRAIN

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Valproic acid improves locomotion in vivo after SCI and axonal growth of neurons in vitro

(2011) Lei Lv et al.   EXPERIMENTAL NEUROLOGY

Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells

(2011) H. Wu et al.   GENES & DEVELOPMENT

Epigenetic Regulation of Motor Neuron Cell Death through DNA Methylation

(2011) B. A. Chestnut et al.   JOURNAL OF NEUROSCIENCE

CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

(2011) Sanjeev Shukla et al.   NATURE

Neuronal activity modifies the DNA methylation landscape in the adult brain

(2011) Junjie U Guo et al.   NATURE NEUROSCIENCE

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

(2011) Keith E Szulwach et al.   NATURE NEUROSCIENCE

Axotomy-Induced miR-21 Promotes Axon Growth in Adult Dorsal Root Ganglion Neurons

(2011) Iain T. Strickland et al.   PLoS One

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylation

(2010) Dengke K. Ma et al.   CELL CYCLE

HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation

(2010) P Gaub et al.   CELL DEATH AND DIFFERENTIATION

Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation

(2010) Bermans J. Iskandar et al.   JOURNAL OF CLINICAL INVESTIGATION

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

(2010) Quincey LaPlant et al.   NATURE NEUROSCIENCE

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

(2009) D. K. Ma et al.   SCIENCE

KLF Family Members Regulate Intrinsic Axon Regeneration Ability

(2009) D. L. Moore et al.   SCIENCE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Nerve injury signaling

(2008) Namiko Abe et al.   CURRENT OPINION IN NEUROBIOLOGY

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS