Article
Microbiology
Nadine Lerche, Silva Holtfreter, Birgit Walther, Torsten Semmler, Fawaz Al'Sholui, Stephanie J. Dancer, Georg Daeschlein, Nils-Olaf Huebner, Barbara M. Broeker, Roald Papke, Thomas Kohlmann, Romy Baguhl, Ulrike Seifert, Axel Kramer
Summary: The prevalence of MSSA among dental health care workers in Mecklenburg Western-Pomerania, Germany was found to be 22.3%, while MRSA was not detected. Spa typing revealed most spa types were identified only once, and WGS data analysis confirmed close clonal relationships for some isolate pairs. Widespread use of PPE among dentists and assistants suggests adherence to routine hygiene protocols and may be protective against MRSA.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
(2021)
Article
Infectious Diseases
Katarina Pomorska, Vladislav Jakubu, Lucia Malisova, Marta Fridrichova, Martin Musilek, Helena Zemlickova
Summary: This study aimed to characterize methicillin-resistant Staphylococcus aureus (MRSA) isolates from the blood of hospitalized patients in the Czech Republic between 2016 and 2018. The majority of MRSA strains were found to be resistant to several antibiotics, with 52 different spa types identified in the analyzed strains. The CC5 clonal complex was predominant in this study, with other CCs such as CC398, CC22, CC8, CC45, and CC97 also present.
Article
Microbiology
Heather T. Essigmann, Craig L. Hanis, Stacia M. DeSantis, William B. Perkison, David A. Aguilar, Goo Jun, D. Ashley Robinson, Eric L. Brown
Summary: This study demonstrates that the odds of intermittent but not persistent nasal carriage of S. aureus significantly increases with worsening measures of dysglycemia.
MICROBIOLOGY SPECTRUM
(2022)
Article
Microbiology
Luka Cvetnic, Marko Samardzija, Sanja Duvnjak, Boris Habrun, Marija Cvetnic, Vesna Jaki Tkalec, Drazen Duricic, Miroslav Benic
Summary: This study analyzed 237 strains of S. aureus isolated from cows with subclinical mastitis, and found that most of the isolates carried the spa fragment. The spa typing and MLST revealed a diverse group of S. aureus strains, suggesting potential zoonotic transmission that would require further investigation on humans and livestock in farms.
Article
Ecology
Sylwia Banaszkiewicz, Aleksandra Tabis, Bartosz Walecki, Karolina Lyzwinska, Jaroslaw Bystron, Jacek Bania
Summary: Little is known about the structure of S. aureus population and the enterotoxin gene content in wild boar. In this study, 121 S. aureus isolates were identified from nasal swabs of wild boars, and 18 isolates were found to carry staphylococcal enterotoxin (SE) genes. The production of SEs was evaluated in microbial broth, and various concentrations of SEs were detected. Thirty-nine spa types were identified among the S. aureus isolates, including 12 new spa types. The findings suggest that wildlife animals, such as wild boars, may serve as a significant reservoir of see-positive S. aureus.
Article
Biochemistry & Molecular Biology
Stefano Ravaioli, Davide Campoccia, Werner Ruppitsch, Franz Allerberger, Alessandro Poggi, Emanuele Chisari, Lucio Montanaro, Carla Renata Arciola
Summary: This study evaluated the usefulness of automated ribotyping as a screening tool for identifying S. aureus genetic lineages. Results showed that automated ribotyping can predict spa and MLST clonal complexes, but its high cost and lower discriminatory power could be obstacles for fine genotyping analysis. However, automated ribotyping has advantages such as automation, ease of execution, stability, typeability, and reproducibility, making it a reliable method to be used alongside gold standard methods.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Sherry Usun Jones, Kek Heng Chua, Ching Hoong Chew, Chew Chieng Yeo, Fatimah Haslina Abdullah, Norlela Othman, Boon Pin Kee, Suat Moi Puah
Summary: This study aimed to investigate the spa types of Malaysian S. aureus isolates from various clinical specimens. The results showed that spa type t032 was the most predominant in MRSA, while t127 and t091 were the most common in MSSA.
Article
Multidisciplinary Sciences
Valerie O. Baede, Anais Barray, Mehri Tavakol, Gerard Lina, Margreet C. Vos, Jean-Philippe Rasigade
Summary: The use of topical antimicrobial drugs for nasal decolonization against Staphylococcus aureus can impact the nasal microbiota. This study found that treatment with mupirocin effectively eliminated S. aureus and certain other species, but not corynebacteria. S. aureus recolonization in carriers was faster than recolonization by dominant species in noncarriers.
SCIENTIFIC REPORTS
(2022)
Article
Infectious Diseases
Mulemba Tillika Samutela, Bruno Stephen July Phiri, Edgar Simulundu, Geoffrey Kwenda, Ladslav Moonga, Eugene C. Bwalya, Walter Muleya, Therese Nyirahabimana, Kaunda Yamba, Henson Kainga, Simegnew Adugna Kallu, Innocent Mwape, Andrew Frey, Matthew Bates, Hideaki Higashi, Bernard Mudenda Hang'ombe
Summary: This study investigated the prevalence, phenotypic and genotypic characteristics of Staphylococcus aureus in pigs and workers at farms and abattoirs in Lusaka Province of Zambia. The results showed that S. aureus had a certain prevalence in both pigs and humans, and exhibited resistance to multiple antibiotics. The study suggests the need for continuous surveillance of S. aureus infections and the spread of antimicrobial resistance.
Article
Infectious Diseases
Gustavo Freu, Tiago Tomazi, Antonio F. S. Filho, Marcos B. Heinemann, Marcos dos Santos
Summary: Staphylococcus aureus is a contagious pathogen associated with bovine mastitis in Brazil. Molecular characterization of Staph. aureus isolates from affected cows provided data on the epidemiology and genetic-level antimicrobial susceptibility (AMS). The study found high genotypic similarity among Staph. aureus isolates within and between herds, with resistance to most antibiotics, particularly beta-lactam antibiotics.
Article
Microbiology
Ricardo Oliveira, Eva Pinho, Goncalo Almeida, Nuno F. Azevedo, Carina Almeida
Summary: This study investigated the prevalence and genetic diversity of Staphylococcus aureus and staphylococcal enterotoxins in raw milk from the main dairy region of mainland Portugal. The results showed the presence of S. aureus in raw cow's milk samples, with some samples containing multiple strains. Antimicrobial susceptibility testing revealed resistance to various drugs in a portion of the isolates. Methicillin-resistant S. aureus (MRSA) strains and isolates carrying enterotoxin-encoding genes were also identified. These findings emphasize the need for enhanced monitoring and control measures to prevent S. aureus transmission in the food chain in Portugal.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Gernot Zarfel, Julia Schmidt, Josefa Luxner, Andrea J. Grisold
Summary: MRSA is a universal threat, but the COVID-19 pandemic did not have a significant impact on MRSA dynamics in Austria.
Article
Microbiology
Kevin Bouiller, Abdeljalil Zeggay, Houssein Gbaguidi-Haore, Didier Hocquet, Catherine Chirouze, Xavier Bertrand
Summary: This study aimed to determine the prevalence and factors associated with nasal carriage of Staphylococcus aureus CC398 in the community and among hospitalized patients. The results showed a higher prevalence of MSSA CC398 in the community compared to hospitalized patients. Factors associated with nasal carriage of MSSA CC398 were primarily related to general preconditions and not related to contact with livestock.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Flora M. Petroczki, Akos Pasztor, Kata D. Szilcs, Karoly Pal, Gabor Kardos, Ervin Albert, Brigitta Horvath, Erika Ungvari, Bela Beri, Ferenc Peles
Summary: The research aimed to assess the occurrence of Staphylococcus aureus in a Hungarian large-scale dairy farm during a control program. S. aureus was detected in all bulk tank milk samples collected during the study, with two different spa types identified among the 17 strains. Most strains were susceptible to antibiotics tested, except for penicillin G to which all strains were resistant.
Article
Immunology
Benjamin Russakoff, Colin Wood, Monica R. Lininger, Steven D. Barger, Robert T. Trotter, Sara Maltinsky, Mimi Mbegbu, Briana Coyne, David Panisello Yaguee, Shari Kyman, Kara Tucker-Morgan, Kathya Ceniceros, Cristina Padilla, Kevin Hurtado, Ashley Menard, Francisco Villa, Heidi A. Wayment, Crystal Hepp, Tara Furstenau, Viacheslav Fofanov, Cindy M. Liu, Talima R. Pearson
Summary: This study provides new insights into S aureus carriage by assessing pathogen load and prevalence. The results suggest that current detection and understanding of carriage may be inaccurate, which hinders effective infection mitigation.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Letter
Dermatology
Wenxin Zhang, Xiangqian Li, Bofu Chen, Jianzhong Zhang, Cheng Zhou
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
(2023)
Letter
Dermatology
Lingzhi Zhong, Houmin Li, Jianzhong Zhang
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Optics
Zhongrui Han, Fengjun Tian, Yipeng Lu, Guanqu Hu, Youzhi Chen, Zhibin Zeng, Chao Liu, Xinghua Yang, Li Li, Jianzhong Zhang
Summary: A single-polarization hollow core anti-resonant fiber (HC-ARF) in the terahertz (THz) region is proposed, with excellent single-polarization behavior achieved through material parameter optimization. The introduction of epsilon-near-zero (ENZ) material into high resistance silicon tubes further improves the single polarization behavior, enlarging the polarization extinction ratio (PER) and greatly improving birefringence. Configuration parameter optimization is conducted to obtain high PER and birefringence at 1 THz. The proposed single-polarization HC-ARF has great potential applications in polarization sensitive communication and THz band sensors.
Article
Immunology
Qi Zhao, Yu-Meng Jing, Mao-Tao He, Li Jing, Yan-Feng Xi, Jian-Zhong Zhang
Summary: Lycium barbarum polysaccharides (LBP) can ameliorate cerebral ischemia/reperfusion injury exacerbated by hyperglycemia by protecting the blood-brain barrier. The study found that LBP pretreatment reversed the increase in neurological deficit, infarct volume, cell apoptosis, and IgG leakage associated with hyperglycemia. Furthermore, LBP therapy also reversed the detrimental effects on endothelium, astrocytes, tight junctions, and basement membrane integrity caused by hyperglycemia.
TRANSPLANT IMMUNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Yiran Li, Dong Zhao, Xueyi Ma, Jianzhong Zhang, Jian Zhao
Summary: This paper proposes a panoramic displacement field measurement method to accurately measure the shape and panoramic displacement field of objects with complex morphologies. The method is based on the robust subset-based DIC algorithm and Zhang's calibration method, and it reconstructs the 3D shape and estimates the full-field displacements of complex surfaces from multi-view stereo camera pairs. The proposed method also determines the scale factor of the 3D reconstructed surface and stitches multiple 3D reconstructed surfaces using laser point cloud data. The experimental results confirm the accuracy of the proposed method in measuring panoramic shape and full-field displacement of complex objects.
APPLIED SCIENCES-BASEL
(2023)
Article
Microbiology
Jie Gong, Xin-Fei Chen, Xin Fan, Juan Xu, Han Zhang, Ruo-Yu Li, Sharon C-A Chen, Fanrong Kong, Shu Zhang, Zi-Yong Sun, Mei Kang, Kang Liao, Da-Wen Guo, Zhe Wan, Zhi-Dong Hu, Yun-Zhuo Chu, Hong-Mei Zhao, Gui-Ling Zou, Chong Shen, Yuan-Yuan Geng, Wei-Wei Wu, He Wang, Fei Zhao, Xin Lu, Li-Hua He, Gui-Ming Liu, Ying-Chun Xu, Jian-Zhong Zhang, Meng Xiao
Summary: This study presents the population structure of 551 global C. albicans strains, with 370 strains' antifungal susceptibilities tested. The results show that 66.6% of the azole-nonsusceptible/non-wild-type strains belong to Clade 1. Within Clade 1, two nested subclades (Clade 1-R and Clade 1-R-alpha) exhibit higher azole resistance and are distributed in different cities in China. This study highlights the importance of monitoring the spread of these drug-resistant subclades for public health.
MICROBIOLOGY SPECTRUM
(2023)
Article
Dermatology
Zirui Gao, Yuanqing Dou, Pei Zhao, Caroline J. Wang, Jianzhong Zhang
Summary: This retrospective cohort study evaluated the efficacy and safety of dupilumab in the treatment of prurigo nodularis in adults. The results showed that dupilumab was effective in reducing pruritus and improving the quality of life for patients with prurigo nodularis. It was also found to be safe, with minimal adverse events, making it a potential therapeutic option.
Article
Gastroenterology & Hepatology
Kangle Zhai, Yanan Gong, Lu Sun, Lihua He, Zhijing Xue, Yaming Yang, Mengyang Fang, Jianzhong Zhang
Summary: Using IgY for H. pylori detection is more advantageous than for treatment. DNA starvation/stationary phase protection protein was identified as an immunodominant antigen of H. pylori and may serve as a potential antigen target for the diagnosis of H. pylori infection.
Article
Engineering, Electrical & Electronic
Min Zhang, Zhihai Liu, Yu Zhang, Yaxun Zhang, Jianzhong Zhang, Xinghua Yang, Libo Yuan
Summary: This study proposes a method to use natural spider dragline silk (SDS) as a flexible light waveguide integrated into an optic device. By coupling the light propagating in a microfiber into the SDS, and then coupling it to another microfiber connected to a spectrometer, the output multimode interference spectrum can be changed based on the difference in the effective refractive index of the modes in the silk fiber. The presented interferometer proves that SDS is a natural independent light guide suitable for integrated optic devices.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Microbiology
Yahui Guo, Xiaojie Yu, Jixiao Wang, De Hua, Yuanhai You, Qingbo Wu, Qinglong Ji, Jianzhong Zhang, Liefei Li, Yuan Hu, Zhonghui Wu, Xiaoyue Wei, Lianqun Jin, Fanliang Meng, Yuhua Yang, Xiaofeng Hu, Lijin Long, Songnian Hu, Heyuan Qi, Juncai Ma, Wenwen Bei, Xiaomei Yan, Haibin Wang, Zilong He
Summary: ST7 Staphylococcus aureus, which is highly prevalent in humans, pigs, and food in China, has rarely been reported to cause staphylococcal food poisoning (SFP). However, a recent outbreak of SFP caused by ST7 S. aureus strains occurred in two kindergartens in Hainan Province, China. Whole-genome sequencing analysis revealed the genetic characteristics and phylogenetic relationships of these SFP strains and provided insights into the potential risk of this emergent ST7 clone for SFP.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Yanan Gong, Kangle Zhai, Lu Sun, Lihua He, Hairui Wang, Yahui Guo, Jianzhong Zhang
Summary: Increased resistance to metronidazole impairs the efficacy of H. pylori eradication, and increasing the dose of metronidazole may not overcome this resistance in highly resistant strains and may lead to more adverse effects. The study found that truncated mutations in the rdxA gene can effectively identify patients with high-level metronidazole resistance, allowing for personalized treatment and avoiding unnecessary increases in metronidazole dosage.
MICROBIOLOGY SPECTRUM
(2023)
Article
Microbiology
Hairui Wang, Ying Li, Yixin Gu, Guilan Zhou, Xiaoli Chen, Xin Zhang, Zhujun Shao, Jianzhong Zhang, Maojun Zhang
Summary: Nine novel bacterial strains were isolated from the feces of cats and sheep in Beijing, China in 2019 and 2020. Phylogenetic analysis based on 16S rRNA gene sequences identified two new species within the genus Campylobacter, distinct from currently recognized species. The proposed names for these new species are Campylobacter felis (Type strain XJK22-1(T) = GDMCC 1.3684(T) = JCM 35847(T)) and Campylobacter ovis (Type strain SYS25-1(T) = GDMCC 1.3685(T)).
Review
Dermatology
Yujing Zhang, Jianzhong Zhang, Cheng Zhou
Summary: Perinevoid alopecia (PA) is a rare type of alopecia areata (AA) that is associated with a pigmented nevus in the center. Two cases of PA were reported in this study, and a review of 14 cases from 11 previous studies was conducted. In one of the cases, PA was found to be combined with a halo nevus, and white terminal hairs were spared in the area of hair loss, which is rarely reported in the literature. It is suggested that antigens from melanocytes may be involved in the development of AA in PA.
CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY
(2023)
Article
Microbiology
Hairui Wang, Yixin Gu, Lihua He, Lu Sun, Guilan Zhou, Xiaoli Chen, Xin Zhang, Zhujun Shao, Jianzhong Zhang, Maojun Zhang
Summary: Campylobacter is a main cause of gastroenteritis worldwide. A novel bacterial strain called Campylobacter gastrosuis sp. nov. was isolated from the gastric mucous of pigs in China in 2022.
Article
Oncology
Jiayi Zang, Ming Cui, Lin Xiao, Jianzhong Zhang, Rongrong Jing
Summary: In this study, the higher expression of FSP1 and CISD1 in gastric cancer tissues was associated with poor prognosis and potential immunotherapeutic targets. They were found to promote malignant tumor progression and inhibit ferroptosis in gastric cancer.
CLINICAL & TRANSLATIONAL ONCOLOGY
(2023)