Article
Cardiac & Cardiovascular Systems
Pernille Gro Thrane, Kevin Kris Warnakula Olesen, Troels Thim, Christine Gyldenkerne, Martin Bodtker Mortensen, Steen Dalby Kristensen, Michael Maeng
Summary: In Western Denmark, the implementation of primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI) has led to a significant reduction in 1-year mortality, with the greatest decline occurring within the first 30 days after pPCI. This highlights the importance of optimizing early management for improving overall survival in STEMI patients.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Chao Wu, Xiaojin Gao, Ling Li, Quanmin Jing, Weimin Li, Haiyan Xu, Wenbo Zhang, Sidong Li, Yanyan Zhao, Yang Wang, Wei Li, Yongjian Wu, Fenghuan Hu, Chen Jin, Shubin Qiao, Jingang Yang, Yuejin Yang
Summary: This study evaluated the role of ST-segment resolution (STR) and Thrombolysis in Myocardial Infarction (TIMI) flow in reperfusion evaluation after primary percutaneous coronary intervention (PPCI) for ST-segment-elevation myocardial infarction. The results showed that STR =50% and complete STR were significantly associated with lower 2-year mortality compared to STR <50%. Additionally, the combination of STR and TIMI flow provided incremental prognostic information beyond either measure alone.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Medicine, General & Internal
Yong Hoon Kim, Ae-Young Her, Seung-Woon Rha, Cheol Ung Choi, Byoung Geol Choi, Ji Bak Kim, Soohyung Park, Dong Oh Kang, Ji Young Park, Sang-Ho Park, Myung Ho Jeong
Summary: Using a new-generation drug-eluting stent, the study compared the 2-year clinical outcomes of patients with diabetes mellitus (DM) and non-DM concomitant with a non-ST-segment elevation myocardial infarction (NSTEMI) and an ST-segment elevation myocardial infarction (STEMI) who underwent percutaneous coronary intervention. The results showed higher non-CD rates in patients with DM and higher CD rates in patients without DM in the NSTEMI group.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Yong Hoon Kim, Ae-Young Her, Myung Ho Jeong, Byeong-Keuk Kim, Sung-Jin Hong, Seung-Jun Lee, Chul-Min Ahn, Jung-Sun Kim, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
Summary: The study compared the 2-year major clinical outcomes between STEMI and NSTEMI patients who are current smokers treated with PCI, and found no significant difference in outcomes. Further research is needed to confirm these results.
Article
Medicine, General & Internal
Steffen Desch, Anne Freund, Ibrahim Akin, Michael Behnes, Michael R. Preusch, Thomas A. Zelniker, Carsten Skurk, Ulf Landmesser, Tobias Graf, Ingo Eitel, Georg Fuernau, Hendrik Haake, Peter Nordbeck, Fabian Hammer, Stephan B. Felix, Christian Hassager, Thomas Engstrom, Stephan Fichtlscherer, Jakob Ledwoch, Karsten Lenk, Michael Joner, Stephan Steiner, Christoph Liebetrau, Ingo Voigt, Uwe Zeymer, Michael Brand, Roland Schmitz, Jan Horstkotte, Claudius Jacobshagen, Janine Poss, Mohamed Abdel-Wahab, Philipp Lurz, Alexander Jobs, Suzanne de Waha-Thiele, Denise Olbrich, Frank Sandig, Inke R. Koenig, Sabine Brett, Maren Vens, Kathrin Klinge, Holger Thiele
Summary: Among patients with resuscitated out-of-hospital cardiac arrest without ST-segment elevation, the immediate angiography strategy did not provide any benefit over a delayed or selective strategy in terms of the 30-day risk of death from any cause.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Jihoon Kim, Young Bin Song, Ju-Hyeon Oh, Deok-Kyu Cho, Jin Bae Lee, Sang-Hyun Kim, Jin-Ok Jeong, Jang-Ho Bae, Byung Ok Kim, Jang Hyun Cho, Il-Woo Suh, Doo-il Kim, Hoon-Ki Park, Jong-Seon Park, Woong Gil Choi, Wang Soo Lee, Ki Hong Choi, Taek Kyu Park, Joo Myung Lee, Jeong Hoon Yang, Jin-Ho Choi, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Joon-Hyung Doh, Joo-Yong Hahn
Summary: Prolonged dual antiplatelet therapy (DAPT) for 12 months or more can reduce the risk of recurrent myocardial infarction or stent thrombosis regardless of the type of myocardial infarction. However, it also increases the risk of bleeding.
CIRCULATION JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Samian Sulaiman, Akram Kawsara, Mohamed O. Mohamed, Harriette G. C. Van Spall, Nadia Sutton, David R. Holmes, Mamas A. Mamas, Mohamad Alkhouli
Summary: The study found that women are less likely to receive primary percutaneous coronary intervention (pPCI) than men. However, the reduction in in-hospital mortality with pPCI is comparable between men and women. Despite this, the rates of pPCI remain lower in women in contemporary US practice.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Juan Carlos C. Montoy, Yu-Chu Shen, Ralph G. Brindis, Harlan M. Krumholz, Renee Y. Hsia
Summary: The study found that regionalization programs for ST-segment-elevation myocardial infarction did not have a statistically significant impact on the treatment and outcomes of patients with NSTEMIs. Over the study period, there were slight increases in early angiography rates and decreases in mortality rates, but these changes were not directly related to regionalization policies.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Public, Environmental & Occupational Health
Maarten J. G. Leening, Nathalie I. Bouwer, M. Arfan Ikram, Maryam Kavousi, Rikje Ruiter, Eric Boersma, Ewout-Jan van den Bos, Auke P. J. D. Weevers, Jaap W. Deckers, Mark-David Levin
Summary: Analysis of administrative databases suggests a higher incidence of cancer among individuals who experienced a myocardial infarction, especially within the first 6 months. However, it remains unclear whether this is due to a biological link or the detection of pre-symptomatic cancers and shared risk factors. A study comparing the cancer incidence between thrombotic ST-segment-elevation myocardial infarction patients and the general population found no significant difference over a 5-year follow-up, but a higher incidence was observed in the first 3 months after the myocardial infarction.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Laurent Faroux, Thibault Lhermusier, Flavien Vincent, Luis Nombela-Franco, Didier Tchetche, Marco Barbanti, Mohamed Abdel-Wahab, Stephan Windecker, Vincent Auffret, Diego Carter Campanha-Borges, Quentin Fischer, Erika Munoz-Garcia, Ramiro Trillo-Nouche, Troels Jorgensen, Vicens Serra, Stefan Toggweiler, Giuseppe Tarantini, Francesco Saia, Eric Durand, Pierre Donaint, Enrique Gutierrez-Ibanes, Harindra C. Wijeysundera, Gabriela Veiga, Giuseppe Patti, Fabrizio D'Ascenzo, Raul Moreno, Christian Hengstenberg, Chekrallah Chamandi, Lluis Asmarats, Rosana Hernandez-Antolin, Joan Antoni Gomez-Hospital, Juan Gabriel Cordoba-Soriano, Uri Landes, Victor Alfonso Jimenez-Diaz, Ignacio Cruz-Gonzalez, Mohammed Nejjari, Francois Roubille, Eric Van Belle, German Armijo, Saifullah Siddiqui, Giuliano Costa, Sameh Elsaify, Thomas Pilgrim, Herve le Breton, Marina Urena, Antonio Jesus Munoz-Garcia, Lars Sondergaard, Montserrat Bach-Oller, Chiara Fraccaro, Helene Eltchaninoff, Damien Metz, Maria Tamargo, Victor Fradejas-Sastre, Andrea Rognoni, Francesco Bruno, Georg Goliasch, Marcelo Santalo-Corcoy, Jesus Jimenez-Mazuecos, John G. Webb, Guillem Muntane-Carol, Jean-Michal Paradis, Antonio Mangieri, Henrique Barbosa Ribeiro, Francisco Campelo-Parada, Josep Rodes-Cabau
Summary: The study aimed to investigate the clinical characteristics, management, and outcomes of ST-segment elevation myocardial infarction (STEMI) after transcatheter aortic valve replacement (TAVR). Results showed that patients with STEMI after TAVR had longer door-to-balloon times and a higher PCI failure rate, leading to poorer outcomes attributed to coronary access issues specific to the TAVR population.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Saraschandra Vallabhajosyula, Dhiran Verghese, Malcolm R. Bell, Dennis H. Murphree, Wisit Cheungpasitporn, Paul Elliott Miller, Shannon M. Dunlay, Abhiram Prasad, Gurpreet S. Sandhu, Rajiv Gulati, Mandeep Singh, Amir Lerman, Bernard J. Gersh, David R. Holmes, Gregory W. Barsness
Summary: This study compared the outcomes of patients with STEMI-CS receiving initial fibrinolysis versus PPCI, and found that the in-hospital mortality rate was comparable between the two groups.
Article
Cardiac & Cardiovascular Systems
Andreas Baumbach, Yu-Xin Cui, Rebecca N. Evans, Lucy Culliford, Tom Johnson, Chris A. Rogers, Barnaby C. Reeves, Chiara Bucciarelli-Ducci, Jessica Harris, Mark Hamilton, Paolo Madeddu
Summary: This study investigates the influence of myocardial infarction severity and diabetes on the migratory activity of CD34+/CXCR4+ progenitor cells and attempts to predict cardiac outcomes. The results show an interaction between infarct and diabetes on the migratory activity of CD34+/CXCR4+ cells, but the test does not accurately predict functional outcomes in patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Hematology
Oliver Buchhave Pedersen, Anne-Mette Hvas, Leonardo Pasalic, Steen Dalby Kristensen, Erik Lerkevang Grove, Peter H. Nissen
Summary: This study explored the association between miRNA expression and platelet function and maturity in patients with acute STEMI and healthy individuals. The expression of miR-26b-5p showed the most consistent association with platelet function in STEMI patients and may potentially influence the effect of antiplatelet therapy.
THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Medicine, General & Internal
Teng Yuan, Aikebai Aisan, Tunike Maheshati, Ren Tian, Yunxia Li, You Chen
Summary: A novel score system combining leucocyte and platelet counts (COL-P) scores was found to be useful in predicting adverse outcomes in patients with acute ST segment elevation myocardial infarction (STEMI) after primary percutaneous coronary intervention (PCI).
Article
Geriatrics & Gerontology
Jiachun Lang, Chen Wang, Jingxia Zhang, Yuecheng Hu, Lin Wang, Yin Liu, Rongdi Xu, Jikun Wu, Wei Qi, Chunwei Liu, Wenyu Li, Tingting Li, Dongxia Jin, Ao Wei, Le Wang, Hongliang Cong
Summary: This study compared the clinical outcomes of early versus late delayed PCI in elderly patients with STEMI. The results showed that early delayed PCI (12-48 h from symptom onset) is not associated with better long-term clinical outcomes compared with late delayed PCI (48 h-28 days).
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Cell Biology
Haiyi Yu, Xinyu Wang, Xiangning Deng, Youyi Zhang, Wei Gao
MEDIATORS OF INFLAMMATION
(2019)
Review
Integrative & Complementary Medicine
Ya-jun Xue, Ying Xie, Guo-liang Zhao, Bo-da Zhou, Kun Li, Si-yuan Li, Ping Zhang
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Yanbing Li, Qiang Li, Ou Zhang, Xiaonan Guan, Yajun Xue, Siyuan Li, Xianjing Zhuang, Boda Zhou, Guobin Miao
JOURNAL OF CELLULAR BIOCHEMISTRY
(2019)
Article
Biology
Jimin Wu, Xiangning Deng, Juan Gao, Wei Gao, Han Xiao, Xinyu Wang, Youyi Zhang
SCIENCE CHINA-LIFE SCIENCES
(2019)
Article
Cardiac & Cardiovascular Systems
Akehu Alemasi, Ning Cao, Xiangbo An, Jimin Wu, Huijun Gu, Haiyi Yu, Yao Song, Huan Wang, Youyi Zhang, Han Xiao, Wei Gao
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
(2019)
Article
Biochemical Research Methods
Boda Zhou, Yipeng Du, Yajun Xue, Guobin Miao, Taotao Wei, Ping Zhang
PROTEOMICS CLINICAL APPLICATIONS
(2020)
Article
Cardiac & Cardiovascular Systems
Yajun Xue, Boda Zhou, Weimin Wang, Guobin Miao, Ou Zhang, Jie Zhou, Yu Geng, Yanlong Zhai, Chunhui Ren, Ping Zhang
BMC CARDIOVASCULAR DISORDERS
(2019)
Article
Immunology
Yanbing Li, Jie Zhou, Ou Zhang, Xuejiao Wu, Xiaonan Guan, Yajun Xue, Siyuan Li, Xianjing Zhuang, Boda Zhou, Guobin Miao, Lin Zhang
INTERNATIONAL IMMUNOPHARMACOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Yanxin Song, Chuan Ren, Ping Liu, Liyuan Tao, Wei Zhao, Wei Gao
JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH
(2020)
Article
Multidisciplinary Sciences
Ling Xu, Xi Chen, Ming Cui, Chuan Ren, Haiyi Yu, Wei Gao, Dongguo Li, Wei Zhao
Article
Neurosciences
Yanbing Li, Yu Geng, Boda Zhou, Xuejiao Wu, Ou Zhang, Xiaonan Guan, Yajun Xue, Siyuan Li, Xianjing Zhuang, Jie Zhou, Meng Chang, Guobin Miao, Lizhong Wang
Summary: This study investigated the role of GAS5 in AS and found that inhibiting GAS5 promotes the growth of ECs through miR-194-3p targeting TXNIP, providing a basis for the treatment of AS.
MOLECULAR NEUROBIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Bihe Xu, Kun Li, Fang Liu, Lingyun Kong, Jing Yang, Boda Zhou, Tingting Lv, Yuanwei Liu, Fei She, Rong He, Ping Zhang
Summary: This study presented a case of a 22-year-old female with long QT syndrome, treated effectively with mexiletine. The patient showed shortened QTc interval and improved T wave morphology after treatment. Similar symptoms were also found in her family members, suggesting a possible missense mutation in the KCNH2 gene.
INTERNATIONAL HEART JOURNAL
(2021)
Article
Cell Biology
Boda Zhou, Min Xiao, Hao Hu, Xiaoxia Pei, Yajun Xue, Guobin Miao, Jifeng Wang, Wanqi Li, Yipeng Du, Ping Zhang, Taotao Wei
Summary: This study found that SIRT5 may have a cardioprotective effect in response to acute myocardial infarction, possibly through a liver-cardiac crosstalk mechanism, most likely by increasing the secretion of FGF21 and improving energy metabolism.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell & Tissue Engineering
Yajun Xue, Boda Zhou, Jian Wu, Guobin Miao, Kun Li, Siyuan Li, Jie Zhou, Yu Geng, Ping Zhang
CELL TRANSPLANTATION
(2020)
Article
Public, Environmental & Occupational Health
Jun Guo, Boda Zhou, Mengen Zhu, Yifang Yuan, Qian Wang, Hua Zhou, Xiaohui Wang, Tingting Lv, Siyuan Li, Peng Liu, Ying Yang, Ping He, Ping Zhang
EPIDEMIOLOGY AND INFECTION
(2020)