Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγand Suppresses Adipogenesis

The glucocorticoid receptor: cause of or cure for obesity?

(2016) Kezia John et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Rapamycin-mediated mTORC2 inhibition is determined by the relative expression of FK506-binding proteins

(2015) Katherine H. Schreiber et al.   AGING CELL

Biliverdin reductase isozymes in metabolism

(2015) Luke O’Brien et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Glucocorticoid Receptor β Stimulates Akt1 Growth Pathway by Attenuation of PTEN

(2014) Lance A. Stechschulte et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FKBP51 Reciprocally Regulates GRα and PPARγ Activation via the Akt-p38 Pathway

(2014) Lance A. Stechschulte et al.   MOLECULAR ENDOCRINOLOGY

FKBP51 Controls Cellular Adipogenesis through p38 Kinase-Mediated Phosphorylation of GRα and PPARγ

(2014) Lance A. Stechschulte et al.   MOLECULAR ENDOCRINOLOGY

Beneficial Metabolic Effects of Rapamycin Are Associated with Enhanced Regulatory Cells in Diet-Induced Obese Mice

(2014) Kassem Makki et al.   PLoS One

PPARγ and the global map of adipogenesis and beyond

(2014) Martina I. Lefterova et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

FK506 binding proteins: Cellular regulators of intracellular Ca2+ signalling

(2013) Debbi MacMillan   EUROPEAN JOURNAL OF PHARMACOLOGY

Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21

(2013) Terry D. Hinds et al.   Obesity

Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet

(2013) O V Leontieva et al.   Cell Death & Disease

Autoimmune-mediated glucose intolerance in a mouse model of systemic lupus erythematosus

(2012) Curtis L. Gabriel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Evaluation of Synthetic FK506 Analogues as Ligands for the FK506-Binding Proteins 51 and 52

(2012) Ranganath Gopalakrishnan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: A need for screening tools to target interventions

(2012) Mark D. DeBoer   NUTRITION

Protein Phosphatase 5 Mediates Lipid Metabolism through Reciprocal Control of Glucocorticoid Receptor and Peroxisome Proliferator-activated Receptor-γ (PPARγ)

(2011) Terry D. Hinds et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Susceptibility to Diet-Induced Hepatic Steatosis and Glucocorticoid Resistance in FK506-Binding Protein 52-Deficient Mice

(2010) Manya Warrier et al.   ENDOCRINOLOGY

Discovery of Glucocorticoid Receptor-β in Mice with a Role in Metabolism

(2010) Terry D. Hinds et al.   MOLECULAR ENDOCRINOLOGY

Long-term Administration of Rapamycin Reduces Adiposity, but Impairs Glucose Tolerance in High-Fat Diet-fed KK/HlJ Mice

(2009) Geng-Ruei Chang et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Rapamycin Protects Against High Fat Diet–Induced Obesity in C57BL/6J Mice

(2009) Geng-Ruei Chang et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

FKBP51 and Cyp40 are positive regulators of androgen-dependent prostate cancer cell growth and the targets of FK506 and cyclosporin A

(2009) S Periyasamy et al.   ONCOGENE

Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity

(2008) Irene M. Wolf et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY