Extrasynaptic NMDA receptor-induced tau overexpression mediates neuronal death through suppressing survival signaling ERK phosphorylation

Dysregulation of Tau Phosphorylation in Mouse Brain during Excitotoxic Damage

(2017) Zhihou Liang et al.   JOURNAL OF ALZHEIMERS DISEASE

Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers

(2014) M. L. Frandemiche et al.   JOURNAL OF NEUROSCIENCE

A role for tau at the synapse in Alzheimer's disease pathogenesis

(2013) Amy M. Pooler et al.   NEUROPHARMACOLOGY

Tangles, Toxicity, and Tau Secretion in AD – New Approaches to a Vexing Problem

(2013) Kerry L. Gendreau et al.   Frontiers in Neurology

Synaptic Released Zinc Promotes Tau Hyperphosphorylation by Inhibition of Protein Phosphatase 2A (PP2A)

(2012) Xu-Ying Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glutamate Spillover Promotes the Generation of NMDA Spikes

(2011) J. R. Chalifoux et al.   JOURNAL OF NEUROSCIENCE

Tau Mediated Neurodegeneration: An Insight into Alzheimer’s Disease Pathology

(2011) M. Obulesu et al.   NEUROCHEMICAL RESEARCH

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

(2010) Weihong Tu et al.   CELL

Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity

(2010) F. Leveille et al.   JOURNAL OF NEUROSCIENCE

Activation of Extrasynaptic, But Not Synaptic, NMDA Receptors Modifies Amyloid Precursor Protein Expression Pattern and Increases Amyloid-  Production

(2010) K. Bordji et al.   JOURNAL OF NEUROSCIENCE

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

ERK and cell death: ERK1/2 in neuronal death

(2009) Srinivasa Subramaniam et al.   FEBS Journal

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

(2008) F. Léveillé et al.   FASEB JOURNAL