Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells

Premature aging and immune senescence in HIV-infected children

(2016) Ketty Gianesin et al.   AIDS

LMP1 mediates multinuclearity through downregulation of shelterin proteins and formation of telomeric aggregates

(2015) V. Lajoie et al.   BLOOD

Potent Human Telomerase Inhibitors: Molecular Dynamic Simulations, Multiple Pharmacophore-Based Virtual Screening, and Biochemical Assays

(2015) Faezeh Shirgahi Talari et al.   Journal of Chemical Information and Modeling

Dose-Dependent Cytotoxic Effects of Boldine in HepG-2 Cells—Telomerase Inhibition and Apoptosis Induction

(2015) Sakineh Kazemi Noureini et al.   MOLECULES

Cross talk between EBV and telomerase: the role of TERT and NOTCH2 in the switch of latent/lytic cycle of the virus

(2015) S Giunco et al.   Cell Death & Disease

Telomerase Inhibition Decreases Alpha-Fetoprotein Expression and Secretion by Hepatocellular Carcinoma Cell Lines: In Vitro and In Vivo Study

(2015) Roula Tahtouh et al.   PLoS One

Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress

(2014) G. Saretzki   CURRENT PHARMACEUTICAL DESIGN

hTERT Inhibition Triggers Epstein-Barr Virus Lytic Cycle and Apoptosis in Immortalized and Transformed B Cells: A Basis for New Therapies

(2013) S. Giunco et al.   CLINICAL CANCER RESEARCH

Inhibition of Telomerase Recruitment and Cancer Cell Death

(2013) Mai Nakashima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylated (pT371)TRF1 is recruited to sites of DNA damage to facilitate homologous recombination and checkpoint activation

(2013) Megan McKerlie et al.   NUCLEIC ACIDS RESEARCH

Telomere dysfunction and activation of alternative lengthening of telomeres in B-lymphocytes infected by Epstein–Barr virus

(2013) S A Kamranvar et al.   ONCOGENE

Telomerase Contributes to Fludarabine Resistance in Primary Human Leukemic Lymphocytes

(2013) May Shawi et al.   PLoS One

Interplay among viral antigens, cellular pathways and tumor microenvironment in the pathogenesis of EBV-driven lymphomas

(2013) Riccardo Dolcetti et al.   SEMINARS IN CANCER BIOLOGY

The Role of Telomere Biology in Cancer

(2012) Lifeng Xu et al.   Annual Review of Pathology-Mechanisms of Disease

Direct Short-Term Cytotoxic Effects of BIBR 1532 on Acute Promyelocytic Leukemia Cells Through Induction of p21 Coupled with Downregulation of c-Myc and hTERT Transcription

(2012) D. Bashash et al.   CANCER INVESTIGATION

Overexpression of hTERT extends replicative capacity of human nucleus pulposus cells, and protects against serum starvation-induced apoptosis and cell cycle arrest

(2012) Weiguo Liang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Telomerase inhibition by non-nucleosidic compound BIBR1532 causes rapid cell death in pre-B acute lymphoblastic leukemia cells

(2012) Davood Bashash et al.   LEUKEMIA & LYMPHOMA

Epstein-Barr Virus BGLF4 Kinase Retards Cellular S-Phase Progression and Induces Chromosomal Abnormality

(2012) Yu-Hsin Chang et al.   PLoS One

Telomere-independent functions of telomerase in nuclei, cytoplasm, and mitochondria

(2012) Ilaria Chiodi et al.   Frontiers in Oncology

Functional p53 is required for effective execution of telomerase inhibition in BCR-ABL–positive CML cells

(2010) Ute Brassat et al.   EXPERIMENTAL HEMATOLOGY

Purification of Proteins Associated with Specific Genomic Loci

(2009) Jérôme Déjardin et al.   CELL

Chromosomal rearrangements after ex vivo Epstein–Barr virus (EBV) infection of human B cells

(2009) S Lacoste et al.   ONCOGENE

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

Relationship Between Tumor and Plasma Levels of hTERT mRNA in Patients with Colorectal Cancer: Implications for Monitoring of Neoplastic Disease

(2008) L. Terrin et al.   CLINICAL CANCER RESEARCH

Latent Membrane Protein 1 of Epstein-Barr Virus Activates the hTERT Promoter and Enhances Telomerase Activity in B Lymphocytes

(2008) L. Terrin et al.   JOURNAL OF VIROLOGY

DNA Damage Response Pathways in Tumor Suppression and Cancer Treatment

(2008) Yulong Liang et al.   WORLD JOURNAL OF SURGERY