Short-term EGFR blockade enhances immune-mediated cytotoxicity of EGFR mutant lung cancer cells: rationale for combination therapies

EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition

(2015) Fumiyuki Sato et al.   CANCER BIOLOGY & THERAPY

Targeted therapies for treatment of non-small cell lung cancer-Recent advances and future perspectives

(2015) Joan Minguet et al.   INTERNATIONAL JOURNAL OF CANCER

Genomic alterations in lung adenocarcinoma

(2015) Siddhartha Devarakonda et al.   LANCET ONCOLOGY

Treatment approaches for EGFR-inhibitor-resistant patients with non-small-cell lung cancer

(2015) Chee-Seng Tan et al.   LANCET ONCOLOGY

Refining the treatment of NSCLC according to histological and molecular subtypes

(2015) Anish Thomas et al.   Nature Reviews Clinical Oncology

Pembrolizumab for the Treatment of Non–Small-Cell Lung Cancer

(2015) Edward B. Garon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nivolumab versus Docetaxel in Advanced Nonsquamous Non–Small-Cell Lung Cancer

(2015) Hossein Borghaei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive Immune Resistance: How Cancer Protects from Immune Attack

(2015) A. Ribas   Cancer Discovery

IL-8 confers resistance to EGFR inhibitors by inducing stem cell properties in lung cancer

(2015) Yi-Nan Liu et al.   Oncotarget

Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody

(2015) Duane H. Hamilton et al.   Oncotarget

A decade of EGFR inhibition in EGFR-mutated non small cell lung cancer (NSCLC): Old successes and future perspectives

(2015) Alessandro Russo et al.   Oncotarget

EMT, CTCs and CSCs in tumor relapse and drug-resistance

(2015) Abhisek Mitra et al.   Oncotarget

Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury

(2015) C. R. Heery et al.   Cancer Immunology Research

Immunological targeting of tumor cells undergoing an epithelial-mesenchymal transition via a recombinant brachyury-yeast vaccine

(2015) Duane H. Hamilton et al.   Oncotarget

Identification and characterization of a cytotoxic T-lymphocyte agonist epitope of brachyury, a transcription factor involved in epithelial to mesenchymal transition and metastasis

(2014) Jo A. Tucker et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

EGFR Blockade Enriches for Lung Cancer Stem-like Cells through Notch3-Dependent Signaling

(2014) R. R. Arasada et al.   CANCER RESEARCH

WEE1 Inhibition Alleviates Resistance to Immune Attack of Tumor Cells Undergoing Epithelial-Mesenchymal Transition

(2014) D. H. Hamilton et al.   CANCER RESEARCH

Tumor Plasticity Interferes with Anti-Tumor Immunity

(2014) Salem Chouaib et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Pharmacotherapy targeting the EGFR oncogene in NSCLC

(2014) Lorenza Landi et al.   EXPERT OPINION ON PHARMACOTHERAPY

EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition

(2014) Audrey Clapéron et al.   JOURNAL OF HEPATOLOGY

Overexpression of the EMT Driver Brachyury in Breast Carcinomas: Association With Poor Prognosis

(2014) Claudia Palena et al.   JNCI-Journal of the National Cancer Institute

EGFR-mediated tumor immunoescape

(2014) Fernando Concha-Benavente et al.   OncoImmunology

Expression of Brachyury Gene Is a Significant Prognostic Factor for Primary Lung Carcinoma

(2013) Akira Haro et al.   ANNALS OF SURGICAL ONCOLOGY

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

(2013) Intissar Akalay et al.   Autophagy

Identification and characterization of agonist epitopes of the MUC1-C oncoprotein

(2013) Caroline Jochems et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Epithelial-to-Mesenchymal Transition and Autophagy Induction in Breast Carcinoma Promote Escape from T-cell-Mediated Lysis

(2013) I. Akalay et al.   CANCER RESEARCH

Epidermal growth factor receptor tyrosine kinase inhibitors as initial therapy for non-small cell lung cancer: Focus on epidermal growth factor receptor mutation testing and mutation-positive patients

(2013) Monic Roengvoraphoj et al.   CANCER TREATMENT REVIEWS

Brachyury, a Driver of the Epithelial-Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer

(2012) M. Roselli et al.   CLINICAL CANCER RESEARCH

An Epithelial-Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

(2012) L. A. Byers et al.   CLINICAL CANCER RESEARCH

Influence of IL-8 on the epithelial–mesenchymal transition and the tumor microenvironment

(2012) Claudia Palena et al.   Future Oncology

Therapeutic Cancer Vaccines: Current Status and Moving Forward

(2012) J. Schlom   JNCI-Journal of the National Cancer Institute

EGFR inhibitors sensitize non-small cell lung cancer cells to TRAIL-induced apoptosis

(2012) Fei Xu et al.   Chinese Journal of Cancer

EGFR inhibitors, MHC expression and immune responses : Can EGFR inhibitors be used as immune response modifiers?

(2012) Brian P. Pollack   OncoImmunology

Brachyury expression predicts poor prognosis at early stages of colorectal cancer

(2011) Nerbil Kilic et al.   EUROPEAN JOURNAL OF CANCER

EGFR Inhibitors Enhanced the Susceptibility to NK Cell-mediated Lysis of Lung Cancer Cells

(2011) Hyunsu Kim et al.   JOURNAL OF IMMUNOTHERAPY

Optimization of Dosing for EGFR-Mutant Non-Small Cell Lung Cancer with Evolutionary Cancer Modeling

(2011) J. Chmielecki et al.   Science Translational Medicine

Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors

(2011) L. V. Sequist et al.   Science Translational Medicine

Immune Promotion of Epithelial-mesenchymal Transition and Generation of Breast Cancer Stem Cells

(2010) J. M. Reiman et al.   CANCER RESEARCH

The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells

(2010) Romaine I. Fernando et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic Cancer Vaccines in Prostate Cancer: The Paradox of Improved Survival Without Changes in Time to Progression

(2010) R. A. Madan et al.   ONCOLOGIST

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells

(2009) Nawneet K. Kurrey et al.   STEM CELLS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL