CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells

CD95 promotes metastatic spread via Sck in pancreatic ductal adenocarcinoma

(2015) M Teodorczyk et al.   CELL DEATH AND DIFFERENTIATION

Different Levels of Twist1 Regulate Skin Tumor Initiation, Stemness, and Progression

(2015) Benjamin Beck et al.   Cell Stem Cell

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Snail promotes cell migration through PI3K/AKT-dependent Rac1 activation as well as PI3K/AKT-independent pathways during prostate cancer progression

(2015) Veronica Henderson et al.   Cell Adhesion & Migration

A Phase II, Randomized, Study of Weekly APG101+Reirradiation versus Reirradiation in Progressive Glioblastoma

(2014) W. Wick et al.   CLINICAL CANCER RESEARCH

CD95 and CD95L promote and protect cancer stem cells

(2014) Paolo Ceppi et al.   Nature Communications

Death Induced by CD95 or CD95 Ligand Elimination

(2014) Abbas Hadji et al.   Cell Reports

EphA3 Maintains Tumorigenicity and Is a Therapeutic Target in Glioblastoma Multiforme

(2013) Bryan W. Day et al.   CANCER CELL

CD95 in cancer: tool or target?

(2013) Ana Martin-Villalba et al.   TRENDS IN MOLECULAR MEDICINE

The EphA2 Receptor Drives Self-Renewal and Tumorigenicity in Stem-like Tumor-Propagating Cells from Human Glioblastomas

(2012) Elena Binda et al.   CANCER CELL

Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming

(2012) Jieun Lee et al.   CELL

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

MEF Promotes Stemness in the Pathogenesis of Gliomas

(2012) Elena Bazzoli et al.   Cell Stem Cell

Pharmacokinetics, pharmacodynamics, safety and tolerability of APG101, a CD95-Fc fusion protein, in healthy volunteers and two glioma patients

(2012) Jochen Tuettenberg et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

(2012) A. G. Schepers et al.   SCIENCE

Human cancer cells express Slug-based epithelial-mesenchymal transition gene expression signature obtained in vivo

(2011) Dimitris Anastassiou et al.   BMC CANCER

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Glioblastoma Models Reveal the Connection between Adult Glial Progenitors and the Proneural Phenotype

(2011) Liang Lei et al.   PLoS One

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion

(2010) Y Wu et al.   BRITISH JOURNAL OF CANCER

TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

(2010) Judit Anido et al.   CANCER CELL

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Integrin Alpha 6 Regulates Glioblastoma Stem Cells

(2010) Justin D. Lathia et al.   Cell Stem Cell

In Vivo Fate Mapping and Expression Analysis Reveals Molecular Hallmarks of Prospectively Isolated Adult Neural Stem Cells

(2010) Ruth Beckervordersandforth et al.   Cell Stem Cell

CD95-Ligand on Peripheral Myeloid Cells Activates Syk Kinase to Trigger Their Recruitment to the Inflammatory Site

(2010) Elisabeth Letellier et al.   IMMUNITY

CD95 promotes tumour growth

(2010) Lina Chen et al.   NATURE

SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma

(2009) Myung Jin Son et al.   Cell Stem Cell

The Death Receptor CD95 Activates Adult Neural Stem Cells for Working Memory Formation and Brain Repair

(2009) Nina S. Corsini et al.   Cell Stem Cell

CD133 (Prominin) Negative Human Neural Stem Cells Are Clonogenic and Tripotent

(2009) Yirui Sun et al.   PLoS One

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

(2009) C. J. Creighton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma

(2008) Susanne Kleber et al.   CANCER CELL

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE