E2-25K SUMOylation inhibits proteasome for cell death during cerebral ischemia/reperfusion

Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke

(2015) X Chen et al.   Cell Death & Disease

Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis

(2015) Jun Hamazaki et al.   PLoS Genetics

The HIP2~Ubiquitin Conjugate Forms a Non-Compact Monomeric Thioester during Di-Ubiquitin Synthesis

(2015) Benjamin W. Cook et al.   PLoS One

Reversible 26S Proteasome Disassembly upon Mitochondrial Stress

(2014) Nurit Livnat-Levanon et al.   Cell Reports

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

Oxidative Stress and Pathophysiology of Ischemic Stroke: Novel Therapeutic Opportunities

(2013) Ramon Rodrigo et al.   CNS & Neurological Disorders-Drug Targets

Negative Regulation of 26S Proteasome Stability via Calpain-mediated Cleavage of Rpn10 Subunit upon Mitochondrial Dysfunction in Neurons

(2013) Qian Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypothermia for acute ischaemic stroke

(2013) Tzu-Ching Wu et al.   LANCET NEUROLOGY

Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

(2013) Michalis Papadakis et al.   NATURE MEDICINE

Conformational switching of the 26S proteasome enables substrate degradation

(2013) Mary E Matyskiela et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the 26S proteasome with ATP- S bound provides insights into the mechanism of nucleotide-dependent substrate translocation

(2013) P. Sledz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ubiquitin Receptor S5a/Rpn10 Links Centrosomal Proteasomes with Dendrite Development in the Mammalian Brain

(2013) Sidharth V. Puram et al.   Cell Reports

Molecular Model of the Human 26S Proteasome

(2012) Paula C.A. da Fonseca et al.   MOLECULAR CELL

Near-atomic resolution structural model of the yeast 26S proteasome

(2012) F. Beck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of S5b/PSMD5 in Proteasome Inhibition Caused by TNF-α/NFκB in Higher Eukaryotes

(2012) Sang Mi Shim et al.   Cell Reports

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Regulation of Neuronal Oxidative and Nitrosative Stress by Endogenous Protective Pathways and Disease Processes

(2010) Giles E. Hardingham et al.   ANTIOXIDANTS & REDOX SIGNALING

The Immunoproteasome Cleans up after Inflammation

(2010) Sjoerd van Deventer et al.   CELL

DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke

(2010) Weihong Tu et al.   CELL

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

(2010) Ulrike Seifert et al.   CELL

Erythropoietin in stroke: quo vadis

(2010) Murat Digicaylioglu   EXPERT OPINION ON BIOLOGICAL THERAPY

Structural Basis of E2–25K/UBB+1Interaction Leading to Proteasome Inhibition and Neurotoxicity

(2010) Sunggeon Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines

(2010) Yael David et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Inflammation After Stroke: Mechanisms and Therapeutic Approaches

(2010) Muzamil Ahmad et al.   Translational Stroke Research

Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use

(2009) Ulrich Dirnagl et al.   LANCET NEUROLOGY

Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis

(2009) Kwang-Jin Oh et al.   VIROLOGY

E2-25K/Hip-2 regulates caspase-12 in ER stress–mediated Aβ neurotoxicity

(2008) Sungmin Song et al.   JOURNAL OF CELL BIOLOGY

Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats

(2008) Sarah K. McCann et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY