The control of male fertility by spermatid-specific factors: searching for contraceptive targets from spermatozoon’s head to tail

Current updates on laboratory techniques for the diagnosis of male reproductive failure

(2016) SureshC Sikka et al.   ASIAN JOURNAL OF ANDROLOGY

A new mutation identified in SPATA16 in two globozoospermic patients

(2016) Elias ElInati et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

The Mg2+transporter CNNM4 regulates sperm Ca2+homeostasis and is essential for reproduction

(2016) Daisuke Yamazaki et al.   JOURNAL OF CELL SCIENCE

Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme

(2016) Polina V. Danshina et al.   MOLECULAR HUMAN REPRODUCTION

Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing ofAcrbpin the mouse

(2016) Yoshinori Kanemori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Novel Testis-Specific Gene, Ccdc136, Is Required for Acrosome Formation and Fertilization in Mice

(2016) Qiang Geng et al.   Reproductive Sciences

Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice

(2016) Dong U. Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Sodium–hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertility

(2016) Su-Ren Chen et al.   Cell Death & Disease

Transcription Factor RFX2 Is a Key Regulator of Mouse Spermiogenesis

(2016) Yujian Wu et al.   Scientific Reports

TEX101, a glycoprotein essential for sperm fertility, is required for stable expression of Ly6k on testicular germ cells

(2016) Shuichiro Endo et al.   Scientific Reports

Disruption of NHE8 expression impairs Leydig cell function in the testes

(2015) Hua Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Characterization of membrane occupation and recognition nexus repeat containing 3, meiosis expressed gene 1 binding partner, in mouse male germ cells

(2015) Zhi-Bing Zhang et al.   ASIAN JOURNAL OF ANDROLOGY

Dynamic Changes in Equatorial Segment Protein 1 (SPESP1) Glycosylation During Mouse Spermiogenesis1

(2015) Viswanadhapalli Suryavathi et al.   BIOLOGY OF REPRODUCTION

Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation

(2015) Stefan Koch et al.   CELL

SUN4 is essential for nuclear remodeling during mammalian spermiogenesis

(2015) Alessandra Calvi et al.   DEVELOPMENTAL BIOLOGY

Identification and characterization of methylation-dependent/independent DNA regulatory elements in the human SLC9B1 gene

(2015) Priya L. Kumar et al.   GENE

ICA1L forms BAR-domain complexes with PICK1 and is crucial for acrosome formation in spermiogenesis

(2015) J. He et al.   JOURNAL OF CELL SCIENCE

SEPT12 orchestrates the formation of mammalian sperm annulus by organizing core octameric complexes with other SEPT proteins

(2015) Y.-C. Kuo et al.   JOURNAL OF CELL SCIENCE

SEPT12/SPAG4/LAMINB1 Complexes Are Required for Maintaining the Integrity of the Nuclear Envelope in Postmeiotic Male Germ Cells

(2015) Chung-Hsin Yeh et al.   PLoS One

Spata6is required for normal assembly of the sperm connecting piece and tight head–tail conjunction

(2015) Shuiqiao Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toward a rapid and reversible male pill

(2015) J. Castaneda et al.   SCIENCE

Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive

(2015) H. Miyata et al.   SCIENCE

Motile sperm organelle morphology examination (MSOME) can predict outcomes of conventionalin vitrofertilization: A prospective pilot diagnostic study

(2015) Yang Gao et al.   Human Fertility

RFX2 Is a Major Transcriptional Regulator of Spermiogenesis

(2015) W. Stephen Kistler et al.   PLoS Genetics

LRGUK-1 Is Required for Basal Body and Manchette Function during Spermatogenesis and Male Fertility

(2015) Yan Liu et al.   PLoS Genetics

CCNYL1, but Not CCNY, Cooperates with CDK16 to Regulate Spermatogenesis in Mouse

(2015) Zhenzhen Zi et al.   PLoS Genetics

The LINC complex component Sun4 plays a crucial role in sperm head formation and fertility

(2015) E. Pasch et al.   Biology Open

Intracellular pH in sperm physiology

(2014) Takuya Nishigaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Equatorin is not essential for acrosome biogenesis but is required for the acrosome reaction

(2014) Jianxiu Hao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Physiology of Na+/H+ Exchangers in the Male Reproductive Tract: Relevance for Male Fertility1

(2014) Ana D. Martins et al.   BIOLOGY OF REPRODUCTION

Unresolved Questions Concerning Mammalian Sperm Acrosomal Exocytosis1

(2014) Mariano G. Buffone et al.   BIOLOGY OF REPRODUCTION

GPI-Anchored Protein Complex, LY6K/TEX101, Is Required for Sperm Migration into the Oviduct and Male Fertility in Mice1

(2014) Yoshitaka Fujihara et al.   BIOLOGY OF REPRODUCTION

Atg7 is required for acrosome biogenesis during spermatogenesis in mice

(2014) Hongna Wang et al.   CELL RESEARCH

Mammalian Fused is essential for sperm head shaping and periaxonemal structure formation during spermatogenesis

(2014) Yoko Inès Nozawa et al.   DEVELOPMENTAL BIOLOGY

Development of a high-resolution Y-chromosome microarray for improved male infertility diagnosis

(2014) Ryan K.C. Yuen et al.   FERTILITY AND STERILITY

Truncating mutations inTAF4BandZMYND15causing recessive azoospermia

(2014) Özgecan Ayhan et al.   JOURNAL OF MEDICAL GENETICS

Tssk4 is essential for maintaining the structural integrity of sperm flagellum

(2014) Xiaoli Wang et al.   MOLECULAR HUMAN REPRODUCTION

Juno is the egg Izumo receptor and is essential for mammalian fertilization

(2014) Enrica Bianchi et al.   NATURE

A heterozygous mutation of GALNTL5 affects male infertility with impairment of sperm motility

(2014) N. Takasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Haplo-deficiency of ODF1/HSPB10 in mouse sperm causes relaxation of head-to-tail linkage

(2014) Kefei Yang et al.   REPRODUCTION

KATNB1 in the human testis and its genetic variants in fertile and oligoasthenoteratozoospermic infertile men

(2014) L. O'Donnell et al.   Andrology

Mutations in DNAH1, which Encodes an Inner Arm Heavy Chain Dynein, Lead to Male Infertility from Multiple Morphological Abnormalities of the Sperm Flagella

(2013) Mariem Ben Khelifa et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Prss37 Is Required for Male Fertility in the Mouse1

(2013) Chunling Shen et al.   BIOLOGY OF REPRODUCTION

Disruption of a Spermatogenic Cell-Specific Mouse Enolase 4 (Eno4) Gene Causes Sperm Structural Defects and Male Infertility1

(2013) Noriko Nakamura et al.   BIOLOGY OF REPRODUCTION

Integration of the mouse sperm fertilization-related protein equatorin into the acrosome during spermatogenesis as revealed by super-resolution and immunoelectron microscopy

(2013) Chizuru Ito et al.   CELL AND TISSUE RESEARCH

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

(2013) S. Lim et al.   DEVELOPMENT

Role of cyclins in controlling progression of mammalian spermatogenesis

(2013) Debra J. Wolgemuth et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

KIF3A is essential for sperm tail formation and manchette function

(2013) Mari S. Lehti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi network and subsequent acrosome formation in spermiogenesis

(2013) Tomo Funaki et al.   MOLECULAR BIOLOGY OF THE CELL

ADP-ribosylation factor-like 3, a manchette-associated protein, is essential for mouse spermiogenesis

(2013) Y. Qi et al.   MOLECULAR HUMAN REPRODUCTION

Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa

(2013) Y. Fujihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IQ Motif-Containing G ( Iqcg ) Is Required for Mouse Spermiogenesis

(2013) Tanya P. Harris et al.   G3-Genes Genomes Genetics

CRIS—A Novel cAMP-Binding Protein Controlling Spermiogenesis and the Development of Flagellar Bending

(2013) Anke Miriam Krähling et al.   PLoS Genetics

Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes

(2013) Emma A. Hall et al.   PLoS Genetics

Molecular cytogenetic and genetic aspects of globozoospermia: a review

(2012) A. Perrin et al.   ANDROLOGIA

Small-Molecule Inhibition of BRDT for Male Contraception

(2012) Martin M. Matzuk et al.   CELL

Absence of Dpy19l2, a new inner nuclear membrane protein, causes globozoospermia in mice by preventing the anchoring of the acrosome to the nucleus

(2012) V. Pierre et al.   DEVELOPMENT

SPACA1-deficient male mice are infertile with abnormally shaped sperm heads reminiscent of globozoospermia

(2012) Y. Fujihara et al.   DEVELOPMENT

The CatSper channel: a polymodal chemosensor in human sperm

(2012) Christoph Brenker et al.   EMBO JOURNAL

SEPT12mutations cause male infertility with defective sperm annulus

(2012) Yung-Che Kuo et al.   HUMAN MUTATION

Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa

(2012) Ryo Yamaguchi et al.   MOLECULAR BIOLOGY OF THE CELL

Alteration in the processing of the ACRBP/sp32 protein and sperm head/acrosome malformations in proprotein convertase 4 (PCSK4) null mice

(2012) S. Tardif et al.   MOLECULAR HUMAN REPRODUCTION

Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility

(2012) K. Tokuhiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MNS1 Is Essential for Spermiogenesis and Motile Ciliary Functions in Mice

(2012) Jian Zhou et al.   PLoS Genetics

A Recurrent Deletion of DPY19L2 Causes Infertility in Man by Blocking Sperm Head Elongation and Acrosome Formation

(2011) Radu Harbuz et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic causes of spermatogenic failure

(2011) Annelien Massart et al.   ASIAN JOURNAL OF ANDROLOGY

Septins at the annulus of mammalian sperm

(2011) Aminata Toure et al.   BIOLOGICAL CHEMISTRY

Deficiency in the Omega-3 Fatty Acid Pathway Results in Failure of Acrosome Biogenesis in Mice1

(2011) Manuel Roqueta-Rivera et al.   BIOLOGY OF REPRODUCTION

Hsp90b1 knockout targeted to male germline: a mouse model for globozoospermia

(2011) Christophe Audouard et al.   FERTILITY AND STERILITY

Ornithine Decarboxylase AntizymeOaz3Modulates Protein Phosphatase Activity

(2011) Yibing Ruan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Small Heat Shock Protein ODF1/HSPB10 Is Essential for Tight Linkage of Sperm Head to Tail and Male Fertility in Mice

(2011) K. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Cyclin-Dependent Kinase 16/PCTAIRE Kinase 1 Is Activated by Cyclin Y and Is Essential for Spermatogenesis

(2011) P. Mikolcevic et al.   MOLECULAR AND CELLULAR BIOLOGY

Hook2 is involved in the morphogenesis of the primary cilium

(2011) Carole L. Baron Gaillard et al.   MOLECULAR BIOLOGY OF THE CELL

Association of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men

(2011) Alexander N. Yatsenko et al.   MOLECULAR HUMAN REPRODUCTION

Progesterone activates the principal Ca2+ channel of human sperm

(2011) Polina V. Lishko et al.   NATURE

A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa

(2011) Jean-Ju Chung et al.   Nature Communications

A newly discovered mutation in PICK1 in a human with globozoospermia

(2010) Gang Liu et al.   ASIAN JOURNAL OF ANDROLOGY

Genetic male infertility and mutation of CATSPER ion channels

(2010) Michael S Hildebrand et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The genetic causes of male factor infertility: A review

(2010) Katherine L. O'Flynn O'Brien et al.   FERTILITY AND STERILITY

Pregnancy and live birth after autotransplantation of frozen-thawed ovarian tissue in a patient with metastatic disease undergoing chemotherapy and hematopoietic stem cell transplantation

(2010) Jacques Donnez et al.   FERTILITY AND STERILITY

Calsperin Is a Testis-specific Chaperone Required for Sperm Fertility

(2010) Masahito Ikawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zmynd15Encodes a Histone Deacetylase-dependent Transcriptional Repressor Essential for Spermiogenesis and Male Fertility

(2010) Wei Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sperm equatorial segment protein 1, SPESP1, is required for fully fertile sperm in mouse

(2010) Y. Fujihara et al.   JOURNAL OF CELL SCIENCE

UBQLN1 interacts with SPEM1 and participates in spermiogenesis

(2010) Jianqiang Bao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids

(2010) Jianqiang Bao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Expression and localization of five members of the testis-specific serine kinase (Tssk) family in mouse and human sperm and testis

(2010) Y. Li et al.   MOLECULAR HUMAN REPRODUCTION

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Human Male Infertility Caused by Mutations in the CATSPER1 Channel Protein

(2009) Matthew R. Avenarius et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Novel, Single, Transmembrane Protein CATSPERG Is Associated with CATSPER1 Channel Protein1

(2009) Haikun Wang et al.   BIOLOGY OF REPRODUCTION

Disruption of ADAM3 Impairs the Migration of Sperm into Oviduct in Mouse1

(2009) Ryo Yamaguchi et al.   BIOLOGY OF REPRODUCTION

Phosphoglycerate Kinase 2 (PGK2) Is Essential for Sperm Function and Male Fertility in Mice1

(2009) Polina V. Danshina et al.   BIOLOGY OF REPRODUCTION

Spatiotemporal association of DNAJB13 with the annulus during mouse sperm flagellum development

(2009) Jikui Guan et al.   BMC DEVELOPMENTAL BIOLOGY

Immunization with a DNA vaccine of testis-specific sodium-hydrogen exchanger by oral feeding or nasal instillation reduces fertility in female mice

(2009) Tao Liu et al.   FERTILITY AND STERILITY

Acrosome formation-associated factor is involved in fertilization

(2009) Xiao-Qian Hu et al.   FERTILITY AND STERILITY

Absence of annulus in human asthenozoospermia: Case Report†

(2009) P. Lhuillier et al.   HUMAN REPRODUCTION

PICK1 deficiency causes male infertility in mice by disrupting acrosome formation

(2009) Nan Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 1: Background to spermatogenesis, spermatogonia, and spermatocytes

(2009) Louis Hermo et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Male infertility caused by spermiogenic defects: Lessons from gene knockouts

(2009) Wei Yan   MOLECULAR AND CELLULAR ENDOCRINOLOGY

MEIG1 is essential for spermiogenesis in mice

(2009) Z. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OAZ-t/OAZ3 Is Essential for Rigid Connection of Sperm Tails to Heads in Mouse

(2009) Keizo Tokuhiro et al.   PLoS Genetics

Expression of the Gene for Mouse Lactate Dehydrogenase C (Ldhc) Is Required for Male Fertility1

(2008) Fanny Odet et al.   BIOLOGY OF REPRODUCTION

RIM-BP3 is a manchette-associated protein essential for spermiogenesis

(2008) J. Zhou et al.   DEVELOPMENT

Infertility and the provision of infertility medical services in developing countries

(2008) W. Ombelet et al.   HUMAN REPRODUCTION UPDATE

Equatorial Segment Protein (ESP) Is a Human Alloantigen Involved in Sperm-Egg Binding and Fusion

(2008) M. J. Wolkowicz et al.   JOURNAL OF ANDROLOGY

Septins as Diagnostic Markers for a Subset of Human Asthenozoospermia

(2008) Yoshio Sugino et al.   JOURNAL OF UROLOGY