Evolution of Cilia

Late acquisition of mitochondria by a host with chimaeric prokaryotic ancestry

(2016) Alexandros A. Pittis et al.   NATURE

MKS5 and CEP290 Dependent Assembly Pathway of the Ciliary Transition Zone

(2016) Chunmei Li et al.   PLOS BIOLOGY

Loss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory Complex

(2015) Heike Olbrich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ATP Consumption of Eukaryotic Flagella Measured at a Single-Cell Level

(2015) Daniel T.N. Chen et al.   BIOPHYSICAL JOURNAL

Zeta-Tubulin Is a Member of a Conserved Tubulin Module and Is a Component of the Centriolar Basal Foot in Multiciliated Cells

(2015) Erin Turk et al.   CURRENT BIOLOGY

Evolution of the Dynein Heavy Chain Family in Ciliates

(2015) Vidyalakshmi Rajagopalan et al.   JOURNAL OF EUKARYOTIC MICROBIOLOGY

Evolutionary problems in centrosome and centriole biology

(2015) L. Ross et al.   JOURNAL OF EVOLUTIONARY BIOLOGY

Detailed structural and biochemical characterization of the nexin-dynein regulatory complex

(2015) Toshiyuki Oda et al.   MOLECULAR BIOLOGY OF THE CELL

DRC3 connects the N-DRC to dynein g to regulate flagellar waveform

(2015) Junya Awata et al.   MOLECULAR BIOLOGY OF THE CELL

Late steps in cytoplasmic maturation of assembly-competent axonemal outer arm dynein in Chlamydomonas require interaction of ODA5 and ODA10 in a complex

(2015) Anudariya B. Dean et al.   MOLECULAR BIOLOGY OF THE CELL

Complex archaea that bridge the gap between prokaryotes and eukaryotes

(2015) Anja Spang et al.   NATURE

Horizontal gene transfer: building the web of life

(2015) Shannon M. Soucy et al.   NATURE REVIEWS GENETICS

The Flagellar Arginine Kinase in Trypanosoma brucei Is Important for Infection in Tsetse Flies

(2015) Cher-Pheng Ooi et al.   PLoS One

α- and β-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography

(2015) Aditi Maheshwari et al.   STRUCTURE

CCDC151 Mutations Cause Primary Ciliary Dyskinesia by Disruption of the Outer Dynein Arm Docking Complex Formation

(2014) Rim Hjeij et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bioinformatic analysis of ciliary transition zone proteins reveals insights into the evolution of ciliopathy networks

(2014) Amy R Barker et al.   BMC GENOMICS

Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication

(2014) Elif Nur Firat-Karalar et al.   CURRENT BIOLOGY

Six Subgroups and Extensive Recent Duplications Characterize the Evolution of the Eukaryotic Tubulin Protein Family

(2014) Peggy Findeisen et al.   Genome Biology and Evolution

Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activity

(2014) Toshiyuki Oda et al.   JOURNAL OF CELL BIOLOGY

FAP20 is an inner junction protein of doublet microtubules essential for both the planar asymmetrical waveform and stability of flagella in Chlamydomonas

(2014) Haru-aki Yanagisawa et al.   MOLECULAR BIOLOGY OF THE CELL

Multigene eukaryote phylogeny reveals the likely protozoan ancestors of opisthokonts (animals, fungi, choanozoans) and Amoebozoa

(2014) Thomas Cavalier-Smith et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Exploring the evolutionary history of centrosomes

(2014) J. Azimzadeh   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cartwheel assembly

(2014) M. Hirono   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Centriole structure

(2014) M. Winey et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Functional Diversity of Axonemal Dyneins as Assessed by in Vitro and in Vivo Motility Assays ofChlamydomonasMutants

(2014) Ritsu Kamiya et al.   ZOOLOGICAL SCIENCE

Bioenergetic Constraints on the Evolution of Complex Life

(2014) N. Lane   Cold Spring Harbor Perspectives in Biology

From the cytoplasm into the cilium: Bon voyage

(2014) Jarema Malicki et al.   Organogenesis

Molecular paleontology and complexity in the last eukaryotic common ancestor

(2013) V. Lila Koumandou et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Compartmentalized Calcium Signaling in Cilia Regulates Intraflagellar Transport

(2013) Peter Collingridge et al.   CURRENT BIOLOGY

The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility

(2013) Ryosuke Yamamoto et al.   JOURNAL OF CELL BIOLOGY

WD60/FAP163 is a dynein intermediate chain required for retrograde intraflagellar transport in cilia

(2013) Ramila S. Patel-King et al.   MOLECULAR BIOLOGY OF THE CELL

Chlamydomonas ODA10 is a conserved axonemal protein that plays a unique role in outer dynein arm assembly

(2013) Anudariya B. Dean et al.   MOLECULAR BIOLOGY OF THE CELL

The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes

(2013) Raqual Bower et al.   MOLECULAR BIOLOGY OF THE CELL

The roles of evolutionarily conserved functional modules in cilia-related trafficking

(2013) Ching-Hwa Sung et al.   NATURE CELL BIOLOGY

The nexin-dynein regulatory complex subunit DRC1 is essential for motile cilia function in algae and humans

(2013) Maureen Wirschell et al.   NATURE GENETICS

Evolution of modular intraflagellar transport from a coatomer-like progenitor

(2013) T. J. P. van Dam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intraflagellar transport drives flagellar surface motility

(2013) Sheng Min Shih et al.   eLife

Exome Sequencing Identifies Mutations in CCDC114 as a Cause of Primary Ciliary Dyskinesia

(2012) Michael R. Knowles et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Splice-Site Mutations in the Axonemal Outer Dynein Arm Docking Complex Gene CCDC114 Cause Primary Ciliary Dyskinesia

(2012) Alexandros Onoufriadis et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Computer-assisted image analysis of human cilia and Chlamydomonas flagella reveals both similarities and differences in axoneme structure

(2012) Eileen T. O'Toole et al.   Cytoskeleton

Conserved structural motifs in the central pair complex of eukaryotic flagella

(2012) Blanca I. Carbajal-González et al.   Cytoskeleton

Comparative structural analysis of eukaryotic flagella and cilia from Chlamydomonas, Tetrahymena, and sea urchins

(2012) Gaia Pigino et al.   JOURNAL OF STRUCTURAL BIOLOGY

Molecular Phylogeny of Unikonts: New Insights into the Position of Apusomonads and Ancyromonads and the Internal Relationships of Opisthokonts

(2012) Jordi Paps et al.   PROTIST

Cilia at the Node of Mouse Embryos Sense Fluid Flow for Left-Right Determination via Pkd2

(2012) S. Yoshiba et al.   SCIENCE

A late origin of the extant eukaryotic diversity: divergence time estimates using rare genomic changes

(2011) Diana Chernikova et al.   Biology Direct

Rabs and other small GTPases in ciliary transport

(2011) Yi Shan Lim et al.   BIOLOGY OF THE CELL

Structural Basis of the 9-Fold Symmetry of Centrioles

(2011) Daiju Kitagawa et al.   CELL

A unified taxonomy for ciliary dyneins

(2011) Erik F. Y. Hom et al.   Cytoskeleton

The structural heterogeneity of radial spokes in cilia and flagella is conserved

(2011) Jianfeng Lin et al.   Cytoskeleton

Pkd1l1 establishes left-right asymmetry and physically interacts with Pkd2

(2011) S. Field et al.   DEVELOPMENT

Pkd1l1 complexes with Pkd2 on motile cilia and functions to establish the left-right axis

(2011) K. Kamura et al.   DEVELOPMENT

Cilia and Hedgehog: When and how was their marriage solemnized?

(2011) Sudipto Roy   DIFFERENTIATION

Three-dimensional structure of basal body triplet revealed by electron cryo-tomography

(2011) Sam Li et al.   EMBO JOURNAL

Tracing the origins of centrioles, cilia, and flagella

(2011) Zita Carvalho-Santos et al.   JOURNAL OF CELL BIOLOGY

Mechanoreception in motile flagella of Chlamydomonas

(2011) Kenta Fujiu et al.   NATURE CELL BIOLOGY

Cryo-electron tomography reveals conserved features of doublet microtubules in flagella

(2011) D. Nicastro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimating the timing of early eukaryotic diversification with multigene molecular clocks

(2011) L. W. Parfrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures of SAS-6 Suggest Its Organization in Centrioles

(2011) M. van Breugel et al.   SCIENCE

Building the Centriole

(2010) Juliette Azimzadeh et al.   CURRENT BIOLOGY

Ancestral centriole and flagella proteins identified by analysis of Naegleria differentiation

(2010) Lillian K. Fritz-Laylin et al.   JOURNAL OF CELL SCIENCE

Reconstructing the evolutionary history of the centriole from protein components

(2010) M. E. Hodges et al.   JOURNAL OF CELL SCIENCE

cAMP and cGMP signaling: sensory systems with prokaryotic roots adopted by eukaryotic cilia

(2010) Jacque-Lynne F. Johnson et al.   TRENDS IN CELL BIOLOGY

Chlamydomonas CAV2 Encodes a Voltage- Dependent Calcium Channel Required for the Flagellar Waveform Conversion

(2009) Kenta Fujiu et al.   CURRENT BIOLOGY

Centriole evolution

(2009) Wallace F Marshall   CURRENT OPINION IN CELL BIOLOGY

The RJL family of small GTPases is an ancient eukaryotic invention probably functionally associated with the flagellar apparatus

(2009) Marek Elias et al.   GENE

The dynein regulatory complex is the nexin link and a major regulatory node in cilia and flagella

(2009) Thomas Heuser et al.   JOURNAL OF CELL BIOLOGY

Twenty-five dyneins inTetrahymena: A re-examination of the multidynein hypothesis

(2008) David E. Wilkes et al.   CELL MOTILITY AND THE CYTOSKELETON

A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila

(2008) Jeroen Dobbelaere et al.   PLOS BIOLOGY