Review
Chemistry, Multidisciplinary
Jing Wang, Dong-Xia Wang, Bo Liu, Xiao Jing, Dan-Ye Chen, An-Na Tang, Yun-Xi Cui, De-Ming Kong
Summary: DNA nanotechnology utilizes the unique properties and biocompatibility of DNA to construct structurally-defined supramolecular structures, and it has been widely applied in the field of biosensors. With the continuous development of technology, the assembly methods of DNA nanostructures have become more diverse. This review summarizes the latest construction methods and discusses the problems and future directions in this field.
CHEMISTRY-AN ASIAN JOURNAL
(2022)
Article
Multidisciplinary Sciences
Thomas F. Varley, Maria Pope, Maria Grazia Puxeddu, Joshua Faskowitz, Olaf Sporns
Summary: The study introduces a method called partial entropy decomposition (PED) for capturing higher-order dependencies in multivariate data. By applying this method to resting-state fMRI data, the research uncovers robust evidence of higher-order synergies that are typically missed by standard functional connectivity analyses. These findings suggest the existence of unexplored structures in human brain data that may provide insights into the relationship between brain and behavior.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Computer Science, Information Systems
Chun-Xiao Nie
Summary: In this study, the topological structural distance (TSD) is constructed by combining network distance with the k-nearest neighbour network sequence. This indicator is used to quantitatively describe the difference between two sets of points in any metric structure. The results show that TSD can compare the intrinsic structure of low-dimensional and high-dimensional datasets and is applicable to sets of points in discrete space.
INFORMATION SCIENCES
(2024)
Article
Cell Biology
Davide Warm, Davide Bassetti, Jonas Schroer, Heiko J. Luhmann, Anne Sinning
Summary: The early occurrence of calcium transients is strongly linked to neuronal survival, with silent neurons exhibiting a higher probability of cell death. Activity of neighboring neurons in local clusters exerts a pro-survival effect, while networks with a high modular topology are associated with lower cell death rates.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Zhenwen Wang, Lei Mei, Chenxing Guo, Song Huang, Wei-Qun Shi, Xiaowei Li, Wen Feng, Xiaopeng Li, Cheng Yang, Lihua Yuan
Summary: Here we report a ring-in-ring(s) system comprising a hydrogen-bonded macrocycle and cyclobis(paraquat-o-phenylene) tetracation (o-Box) or cyclobis(paraquat-p-phenylene) tetracation (CBPQT(4+), p-Box) that assembles to construct discrete higher order structures with adaptive conformation. This ring-in-ring(s) system features the box-directed aggregation of multiple macrocycles, leading to generation of several stable species such as H4G (1 a/o-Box) and H5G (1 a/o-Box). Remarkably, a dimeric shish-kebab-like ring-in-rings superstructure H7G2 (1 a/o-Box) or H8G2 (1 a/p-Box) is formed from the coaxial stacking of two ring-in-rings units. The formation of such unique dimeric superstructures is attributed to the large pi-surface of this 2D planar macrocycle and the conformational variation of both host and guest.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Cell Biology
Anne Teissier, Alessandra Pierani
Summary: This review discusses the historical and recent advances in the understanding of cortical hierarchy in adults, the similarities and differences in the developmental processes underlying cortical development of primary and higher-order areas, and the potential impact of the dramatic expansion in cortical size on cognitive complexification in evolution. It also explores the alteration of cortical hierarchy in neuropsychiatric disorders and their potential developmental origins.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2021)
Review
Neurosciences
Francisco J. Martini, Teresa Guillamon-Vivancos, Veronica Moreno-Juan, Miguel Valdeolmillos, Guillermina Lopez-Bendito
Summary: Spontaneous activity in developing sensory circuits plays a crucial role in the construction and refinement of functional networks. Originating from various sensory structures, such as the thalamus and cortex, this activity is fundamental for sensory map formation and circuit plasticity. Current data suggest similarities between the developmental trajectory of brain activity in experimental models and humans, offering potential for early diagnosis of developmental disorders.
Article
Clinical Neurology
Hiroya Ono, Masaki Sonoda, Brian H. Silverstein, Kaori Sonoda, Takafumi Kubota, Aimee F. Luat, Robert Rothermel, Sandeep Sood, Eishi Asano
Summary: This study clarified the clinical and mechanistic significance of high-frequency broadband cortical activity associated with spontaneous saccadic eye movements during resting state. The model developed in this study accurately localized the primary visual cortex based on saccade-related high-gamma modulations, with an accuracy of 95%.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Neurosciences
Chuh-Hyoun Na, Kerstin Juetten, Saskia Doreen Forster, Hans Clusmann, Verena Mainz
Summary: Metacognition in brain tumor patients has been minimally studied, with findings revealing preserved metacognitive abilities but decreased connectivity to the whole brain. The dorsomedial prefrontal cortex (DMPFC) connectivity to the whole brain was correlated with memory performance in patients.
Article
Neurosciences
Lennart Luettgau, Emanuele Porcu, Claus Tempelmann, Gerhard Jocham
Summary: This study used functional magnetic resonance imaging data to show that during SOC, visual stimuli can reinstate cortical patterns representing previously paired gustatory outcomes, and there is increased functional covariation between the OFC region and the amygdala in terms of neural pattern similarity. The data suggest a mechanism through which motivational value is conferred to stimuli that were never paired with reinforcement.
Article
Psychology, Multidisciplinary
Asger Kirkeby-Hinrup
Summary: This article presents an empirically based argument for the plausibility of misrepresentation in consciousness. The argument suggests that misrepresentation can occur if conscious states are generated by processes in the brain. The author supports this claim by considering the possibility and frequency of corruption in neural states, and by comparing it with alternative theories.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Multidisciplinary Sciences
Vandana Sampathkumar, Andrew Miller-Hansen, S. Murray Sherman, Narayanan Kasthuri
Summary: The study found that higher order thalamic neurons integrate signals from different cortical populations, with a significant convergence of inputs from the somatosensory and motor cortices on these neurons. These neurons are not simply relaying afferent information but instead integrating signals from disparate cortical regions, indicating a complex role of the higher order thalamus in overall cortical functioning.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Computer Science, Interdisciplinary Applications
Domagoj Bosnjak, Antonio Pepe, Richard Schussnig, Dieter Schmalstieg, Thomas-Peter Fries
Summary: Numerical simulations of the cardiovascular system using patient-specific imaging data are popular due to increased computational power. A new approach for automatic generation of higher-order structured hexahedral meshes of tubular structures is introduced to reduce computational complexity and enhance accuracy. The meshes are generated using skeleton-based convolution surfaces and transfinite mappings, resulting in good quality elements with reduced computing time. The suitability of these meshes is demonstrated through a physiological blood flow simulation in the human aorta using a generalised Newtonian fluid.
ENGINEERING WITH COMPUTERS
(2023)
Review
Engineering, Multidisciplinary
Yonglin Liu, Tianyuan Bian, Yan Liu, Zhimin Li, Yufeng Pei, Jie Song
Summary: DNA is not only a carrier of genetic information, but also a programmable and self-assembled nanomaterial. Different DNA structures are closely related to their biological and chemical functions. Single-molecule methods provide a powerful tool for studying the behavior and heterogeneity of individual DNA molecules. This review discusses the application of single-molecule methods in measuring the properties of DNA structures, including single-stranded/double-stranded DNA, DNA higher-order structures, and DNA nanostructures. The combination of DNA nanotechnology and single-molecule methods offers a new perspective for understanding the biophysical properties of DNA and other bio-matter and soft matter.
Article
Psychology, Multidisciplinary
Camile Bahi, Mona Irrmischer, Katrien Franken, George Fejer, Anna Schlenker, Jan Berend Deijen, Hessel Engelbregt
Summary: Breathwork, specifically connected breathing, has been found to affect brain activity and mood, and induce mystical experiences. This study examined its effects on electroencephalography (EEG) and mood in 20 healthy participants. The results showed decreased delta and theta frequencies in specific brain regions, increased gamma power in experienced practitioners, and improvements in mood, resembling experiences after medium to high doses of psilocybin. These findings suggest that breathwork has potential as a therapeutic modality to improve mental well-being.
CURRENT PSYCHOLOGY
(2023)