Review
Nutrition & Dietetics
Fatema Alkhulaifi, Charles Darkoh
Summary: Dietary patterns and habits play a crucial role in controlling metabolic syndrome risk factors; meal timing and frequency can impact metabolic outcomes.
Article
Orthopedics
L. Kuusalo, D. T. Felson, N. Wang, C. E. Lewis, J. Torner, M. C. Nevitt, T. Neogi
Summary: This study found that there was no significant association between diabetes and cardiovascular disease with prevalent or incident knee osteoarthritis.
OSTEOARTHRITIS AND CARTILAGE
(2021)
Article
Endocrinology & Metabolism
Wanying Hou, Jian Gao, Wenbo Jiang, Wei Wei, Huanyu Wu, Yuntao Zhang, Changhao Sun, Ying Li, Tianshu Han
Summary: The study reveals that overconsumption of low-quality carbohydrates and animal protein at dinner, as opposed to breakfast, is significantly linked to higher cardiovascular disease risk, while consuming unsaturated fatty acids at dinner is associated with lower CVD risk. Substituting low-quality carbohydrates or animal protein with high-quality carbohydrates or plant protein at dinner can reduce the risk of cardiovascular disease.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Nutrition & Dietetics
Sheida Zeraattalab-Motlagh, Azadeh Lesani, Nasim Janbozorgi, Kurosh Djafarian, Maryam Majdi, Sakineh Shab-Bidar
Summary: Accumulative evidence suggests that meal timing is associated with cardiometabolic risks by affecting circadian rhythms. However, the evidence is not clear. This cross-sectional study aimed to investigate the relationship between nightly fasting duration, meal timing, and frequency, and metabolic syndrome (MetS) in Iranian adults. The results showed that longer nightly fasting duration was associated with a lower risk of MetS and elevated TAG, while the energy intake of the first and last meal did not have a significant connection with MetS. These findings suggest that time-related eating patterns may play a role in cardiometabolic risks in Iranian adults.
BRITISH JOURNAL OF NUTRITION
(2023)
Review
Nutrition & Dietetics
Nara Aline Costa, Amanda Gomes Pereira, Mariana de Souza Dorna, Hellen Christina Neves Rodrigues, Paula Schmidt Azevedo, Sergio Alberto Rupp Paiva, Bertha Furlan Polegato, Luis Andre Balbi, Leonardo Antonio Mamede Zornoff, Daniela Ponce, Marcos Ferreira Minicucci
Summary: Nutrition plays a crucial role in the survival of chronic kidney disease (CKD) patients, with specific foods and dietary patterns more important than isolated nutrients. Late-night dinners and skipping meals increase the risk of obesity, insulin resistance, and cardiovascular disease.
Article
Nutrition & Dietetics
Fatema Alkhulaifi, Suad Al-Hooti, Sameer Al-Zenki, Husam AlOmirah, Charles Darkoh
Summary: This study describes the dietary habits of Kuwaiti adults, revealing that a significant portion of adults eat after 10 p.m., skip breakfast and dinner, with women more likely to skip breakfast, and married adults less likely to skip meals. The study emphasizes the importance of further investigating the relationship between meal timing, meal frequency, and the prevalence of NCDs in Kuwait.
Article
Multidisciplinary Sciences
Xi-Meng Wang, Yan Gao, Johan G. Eriksson, Weiqing Chen, Yap Seng Chong, Kok Hian Tan, Cuilin Zhang, Lei Zhou, Ling-Jun Li
Summary: In this study, serum metabolites associated with GDM and postpartum AGM were identified among women in Singapore. These metabolites combined with traditional risk factors showed higher indicative value in predicting AGM compared to traditional models, shedding light on the pathophysiology of the transition from GDM to AGM.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Karolina Drozdz, Katarzyna Nabrdalik, Weronika Hajzler, Hanna Kwiendacz, Janusz Gumprecht, Gregory Y. H. Lip
Summary: Non-alcoholic fatty liver disease (NAFLD) is a common condition associated with type 2 diabetes (T2DM) and cardiovascular disease (CVD). The new term metabolic-associated fatty liver disease (MAFLD) highlights the bidirectional relationships between NAFLD, T2DM, and CVD. Lifestyle changes and targeting the gut microbiota may be important for NAFLD treatment.
Review
Endocrinology & Metabolism
Jacob Bar-Tana
Summary: 'Glucolipotoxicity' and 'insulin resistance' are believed to drive type 2 diabetes and metabolic syndrome, but recent treatments show that alleviating non-glycemic and cardio-renal diseases is possible regardless of glucose lowering and insulin resistance. This opinion article proposes replacing the current paradigm with an 'mammalian target of rapamycin complex 1 (mTORC1) syndrome' (TorS) paradigm, which includes various diseases and may generate novel treatments.
TRENDS IN ENDOCRINOLOGY AND METABOLISM
(2023)
Review
Nutrition & Dietetics
Rikako Yoshitake, Insung Park, Hitomi Ogata, Naomi Omi
Summary: There is a physiological link between sleep and eating, and insufficient sleep can lead to overeating and weight gain. This review examines the effects of dietary timing on sleep and energy metabolism, including time-restricted eating. Time-restricted eating affects the time course of energy metabolism but not total energy expenditure, and it can lead to decreased energy intake and body weight in free-living conditions.
Article
Endocrinology & Metabolism
M. C. Thomas
Summary: Type 2 diabetes and its comorbidities, including cardiovascular disease, heart failure, chronic kidney disease, fatty liver disease, and eye and foot disease, are interrelated and caused by a failure to efficiently manage excessive energy. These conditions worsen each other through shared pathogenesis and subsequent dysfunction. CARAMEL disease, a combination of cardiac, renal, adipo-metabolic, eye, and liver disease, is commonly found in patients with type 2 diabetes. Recent changes in diabetes guidelines emphasize the identification and aggressive management of high-risk individuals.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2022)
Article
Multidisciplinary Sciences
Rieko Bessho, Kazuhiro Kashiwagi, Akihiko Ikura, Karin Yamataka, Jun Inaishi, Hiromasa Takaishi, Takanori Kanai
Summary: This study investigated the association between subclinical atherosclerosis and metabolic dysfunction-associated fatty liver disease (MAFLD) or non-alcoholic fatty liver disease (NAFLD), as well as the synergistic effect of diabetes mellitus (DM) and MAFLD on subclinical atherosclerosis. The results showed that MAFLD was significantly associated with subclinical atherosclerosis in the general population, and DM-MAFLD could be a significant risk factor for cardiovascular disease through insulin resistance and low-grade inflammation.
Article
Endocrinology & Metabolism
Yi Zhang, Chao Liu, Yijing Xu, Yanlei Wang, Fang Dai, Honglin Hu, Tian Jiang, Yunxia Lu, Qiu Zhang
Summary: Multifactorial interventions targeting blood glucose, blood pressure, and lipid profiles can reduce the risk of cardiovascular complications and mortality in patients with type 2 diabetes. This study found associations between health risk behaviors, exercise and diet interventions, and cardiovascular disease. It also highlighted the importance of multifactorial interventions in promoting cardiovascular health.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Chibo Liu, Susu Wu, Xiao Pan
Summary: The study found an association between clustering of CMRFs and pre-diabetes among U.S. adolescents, suggesting the need for effective strategies and measures targeting adolescents with clustering of CMRFs.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Mian Li, Zhiyun Zhao, Guijun Qin, Li Chen, Jieli Lu, Yanan Huo, Lulu Chen, Tianshu Zeng, Min Xu, Yuhong Chen, Tiange Wang, Shuangyuan Wang, Yiping Xu, Lixin Shi, Xulei Tang, Qing Su, Xuefeng Yu, Li Yan, Qin Wan, Gang Chen, Zhengnan Gao, Guixia Wang, Feixia Shen, Zuojie Luo, Yinfei Zhang, Chao Liu, Youmin Wang, Ruying Hu, Zhen Ye, Shengli Wu, Huacong Deng, Tao Yang, Qiang Li, Yingfen Qin, Yiming Mu, Jiajun Zhao, Guang Ning, Yufang Bi, Yu Xu, Weiqing Wang
Summary: The study found that patients with NAFLD had a 15% higher risk of CVD events and a 33% higher risk of CKD compared to those without NAFLD. Among NAFLD patients, individuals with AAR ≥ 1.4 were more likely to experience CVD events.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)