Structural tuning of organoruthenium compounds allows oxidative switch to control ER stress pathways and bypass multidrug resistance

Necroptosis-Inducing Rhenium(V) Oxo Complexes

(2015) Kogularamanan Suntharalingam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium complex Λ-WH0402 induces hepatocellular carcinoma LM6 (HCCLM6) cell death by triggering the Beclin-1-dependent autophagy pathway

(2015) Jian Yuan et al.   Metallomics

Metallodrugs in Medicinal Inorganic Chemistry

(2014) Katja Dralle Mjos et al.   CHEMICAL REVIEWS

Discovery and Investigation of Anticancer Ruthenium–Arene Schiff-Base Complexes via Water-Promoted Combinatorial Three-Component Assembly

(2014) Mun Juinn Chow et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase

(2014) Zuandi Luo et al.   Metallomics

Constitutively Active ErbB2 Regulates Cisplatin-Induced Cell Death in Breast Cancer Cells via Pro- and Antiapoptotic Mechanisms

(2014) Haraldur H. Sigurðsson et al.   MOLECULAR CANCER RESEARCH

Effects of P-Glycoprotein and Its Inhibitors on Apoptosis in K562 Cells

(2014) Yaqiong Zu et al.   MOLECULES

Membrane Localized Iridium(III) Complex Induces Endoplasmic Reticulum Stress and Mitochondria-Mediated Apoptosis in Human Cancer Cells

(2013) Rui Cao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Bidentate Ligands on Osmium(VI) Nitrido Complexes Control Intracellular Targeting and Cell Death Pathways

(2013) Kogularamanan Suntharalingam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Methylation and Apoptosis Resistance in Cancer Cells

(2013) Eric Hervouet et al.   Cells

Induction of caspase 8 and reactive oxygen species by ruthenium-derived anticancer compounds with improved water solubility and cytotoxicity

(2012) Vania Vidimar et al.   BIOCHEMICAL PHARMACOLOGY

Cytotoxic Effects of Jay Amin Hydroxamic Acid (JAHA), a Ferrocene-Based Class I Histone Deacetylase Inhibitor, on Triple-Negative MDA-MB231 Breast Cancer Cells

(2012) Mariangela Librizzi et al.   CHEMICAL RESEARCH IN TOXICOLOGY

An Involvement of Oxidative Stress in Endoplasmic Reticulum Stress and Its Associated Diseases

(2012) Bidur Bhandary et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anticancer gold(i)–phosphine complexes as potent autophagy-inducing agents

(2011) Songhai Tian et al.   CHEMICAL COMMUNICATIONS

Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules

(2011) Muhammad Hanif et al.   CHEMICAL COMMUNICATIONS

Important Role of Caspase-8 for Chemosensitivity of ALL Cells

(2011) H. Ehrhardt et al.   CLINICAL CANCER RESEARCH

Copper Binding Agents Acting as Copper Ionophores Lead to Caspase Inhibition and Paraptotic Cell Death in Human Cancer Cells

(2011) Saverio Tardito et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nuclear Permeable Ruthenium(II) β-Carboline Complexes Induce Autophagy To Antagonize Mitochondrial-Mediated Apoptosis

(2010) Caiping Tan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Tumor resistance to apoptosis

(2008) Simone Fulda   INTERNATIONAL JOURNAL OF CANCER

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS