Selective imaging and cancer cell death via pH switchable near-infrared fluorescence and photothermal effects

A rapid and convenient method for detecting a broad spectrum of malignant cells from malignant pleuroperitoneal effusion of patients using a multifunctional NIR heptamethine dye

(2015) Ying Tian et al.   ANALYST

Hemicyanine-based High Resolution Ratiometric near-Infrared Fluorescent Probe for Monitoring pH Changes in Vivo

(2015) Yinhui Li et al.   ANALYTICAL CHEMISTRY

Enhanced NIR Radiation-Triggered Hyperthermia by Mitochondrial Targeting

(2015) Hyo Sung Jung et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells

(2015) Thomas F. Brewer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-sensitive fluorescent probes: monitoring intracellular iron pools

(2015) Yongmin Ma et al.   Metallomics

A carbohydrate-grafted nanovesicle with activatable optical and acoustic contrasts for dual modality high performance tumor imaging

(2015) Xuanjun Wu et al.   Chemical Science

A sialic acid-targeted near-infrared theranostic for signal activation based intraoperative tumor ablation

(2015) Xuanjun Wu et al.   Chemical Science

Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy

(2014) Zonghai Sheng et al.   ACS Nano

Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells

(2014) Sung-Kyun Ko et al.   Nature Chemistry

Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update

(2014) Muneeb Ahmed et al.   RADIOLOGY

Highly Efficient Hierarchical Micelles Integrating Photothermal Therapy and Singlet Oxygen-Synergized Chemotherapy for Cancer Eradication

(2014) Zhihui Wan et al.   Theranostics

Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology

(2014) Chongwei Chi et al.   Theranostics

pH-activatable near-infrared fluorescent probes for detection of lysosomal pH inside living cells

(2014) Giri K. Vegesna et al.   Journal of Materials Chemistry B

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Imaging acidosis in tumors using a pH-activated near-infrared fluorescence probe

(2012) Lu Wang et al.   CHEMICAL COMMUNICATIONS

An ICT-based strategy to a colorimetric and ratiometric fluorescence probe for hydrogen sulfide in living cells

(2012) Fabiao Yu et al.   CHEMICAL COMMUNICATIONS

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

(2012) Lin Yuan et al.   CHEMICAL SOCIETY REVIEWS

The renaissance of mitochondrial pH

(2012) Jaime Santo-Domingo et al.   JOURNAL OF GENERAL PHYSIOLOGY

Image-guided hepatopancreatobiliary surgery using near-infrared fluorescent light

(2012) Floris P. R. Verbeek et al.   Journal of Hepato-Biliary-Pancreatic Sciences

Application of Near-Infrared Dyes for Tumor Imaging, Photothermal, and Photodynamic Therapies

(2012) Ahu Yuan et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli

(2012) Kejin Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New “Turn-on” Naphthalenedimide-Based Chemosensor for Mercury Ions with High Selectivity: Successful Utilization of the Mechanism of Twisted Intramolecular Charge Transfer, Near-IR Fluorescence, and Cell Images

(2012) Qianqian Li et al.   ORGANIC LETTERS

Translation of Near-Infrared Fluorescence Imaging Technologies: Emerging Clinical Applications

(2011) E.M. Sevick-Muraca   Annual Review of Medicine

Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

(2011) Inthrani R. Indran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A NIR heptamethine dye with intrinsic cancer targeting, imaging and photosensitizing properties

(2011) Xu Tan et al.   BIOMATERIALS

Rational Design of Ratiometric Near-Infrared Fluorescent pH Probes with Various pKaValues, Based on Aminocyanine

(2011) Takuya Myochin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Mitochondria-Targeting Single-Walled Carbon Nanotubes for Cancer Photothermal Therapy

(2011) Feifan Zhou et al.   Small

pH-Activated Near-Infrared Fluorescence Nanoprobe Imaging Tumors by Sensing the Acidic Microenvironment

(2010) Cong Li et al.   ADVANCED FUNCTIONAL MATERIALS

Fluorescence Turn-On Detection of a Protein through the Reduced Aggregation of a Perylene Probe

(2010) Bin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulation of apoptosis-associated lysosomal membrane permeabilization

(2010) Ann-Charlotte Johansson et al.   APOPTOSIS

A near-infrared fluorescent heptamethine indocyanine dye with preferential tumor accumulation for in vivo imaging

(2010) Chao Zhang et al.   BIOMATERIALS

Near IR Heptamethine Cyanine Dye-Mediated Cancer Imaging

(2010) X. Yang et al.   CLINICAL CANCER RESEARCH

Study on intramolecular charge transfer fluorescence properties of trans-4-[4′-(N,N′-dimethylamino)styryl]pyridine: Effect of solvent and pH

(2010) M. Sowmiya et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Selective Targeting of Gold Nanorods at the Mitochondria of Cancer Cells: Implications for Cancer Therapy

(2010) Liming Wang et al.   NANO LETTERS

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

(2010) Thomas Kirkegaard et al.   NATURE

Cyanine dyes in biophysical research: the photophysics of polymethine fluorescent dyes in biomolecular environments

(2010) Marcia Levitus et al.   QUARTERLY REVIEWS OF BIOPHYSICS

A Near-Infrared Neutral pH Fluorescent Probe for Monitoring Minor pH Changes: Imaging in Living HepG2 and HL-7702 Cells

(2009) Bo Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Spectral Properties of Near-Infrared Aminophenyl-, Hydroxyphenyl-, and Phenyl-Substituted Heptamethine Cyanines

(2007) Hyeran Lee et al.   JOURNAL OF ORGANIC CHEMISTRY

Carbazole-Based Donor−Acceptor Compounds:  Highly Fluorescent Organic Nanoparticles

(2007) Sujeewa S. Palayangoda et al.   ORGANIC LETTERS