Review
Ophthalmology
Muriel M. Schornack, Stephen J. Vincent, Maria K. Walker
Summary: Intraocular pressure (IOP) is regulated by complex systems and the use of scleral lenses (SLs) may disrupt these processes. This review examines the anatomical and physiological control of IOP, explores the potential effects of SLs on these mechanisms, and analyzes studies that have attempted to measure the impact of SLs on IOP. Accurate assessment of IOP during SL wear is challenging, but various techniques and instruments have been used to measure IOP before and after lens application, as well as on the peripheral cornea or conjunctiva overlying the sclera. Some conflicting results have been reported regarding changes in IOP during SL wear, particularly for short durations. Long-term effects of SL wear on IOP in habitual wearers are still under-researched. It is important to consider the impact of SLs on corneal biomechanical properties and monitor other risk factors for glaucoma in SL wearers.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
H. Burkhard Dick, Ronald D. Gerste
Summary: The future of intraocular lens (IOL) technology is full of innovations, with a focus on customization, fine-tuning, and correction of presbyopia. New technologies such as extended depth-of-focus IOLs and pinhole IOLs are constantly emerging, representing the future direction of development.
Article
Medicine, General & Internal
Leyi Wang, Xin Wang, Xuepeng Yang, Yuanyuan Si, Jiayin Wu, Yan Cui
Summary: In this study, a theoretical formula for calculating intraocular lens power for silicone oil-dependent eyes was deduced and compared with clinical findings. The results showed no significant difference between the theoretical and clinical refractive powers, indicating a strong correlation between them.
FRONTIERS IN MEDICINE
(2023)
Article
Ophthalmology
Dan Samaha, Langis Michaud
Summary: This study found that scleral lens wear significantly decreases BMO-MRW, which may be attributed to changes in intraocular pressure, and is not affected by corneal rigidity, central corneal thickness, or refractive error. Further research is needed to better understand the significance of these changes at the optic nerve head during scleral lens wear.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2021)
Article
Ophthalmology
Akihiko Shiraki, Susumu Sakimoto, Yoshinori Oie, Takeshi Soma, Atsuya Miki, Shinichi Usui, Shigeru Sato, Kenji Matsushita, Hirokazu Sakaguchi, Kohji Nishida
Summary: This study reports a technique for removing dislocated PMMA intraocular lenses and preserving the function of the filtering bleb, superior cornea and sclera by preserving the intact superior conjunctiva and sclera.
OPHTHALMOLOGY AND THERAPY
(2022)
Article
Ophthalmology
Jad F. Assaf, Dan Z. Reinstein, Cyril Zakka, Juan G. Arbelaez, Peter Boufadel, Mathieu Choufani, Timothy Archer, Perla Ibrahim, Shady T. Awwad
Summary: In this study, a deep learning neural network was developed and validated to automatically measure the vault of implantable collamer lens (ICL) using anterior segment optical coherence tomography (AS-OCT). By using transfer learning, the model achieved high accuracy in estimating the ICL vault from AS-OCT scans with a MAPE of 3.42%, an MAE of 15.82µm, and a Pearson correlation coefficient r of +0.98.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Chemistry, Medicinal
Cristina Minnelli, Francesco Piva, Monia Cecati, Tatiana Armeni, Giovanna Mobbili, Roberta Galeazzi, Alberto Melecchi, Martina Cristaldi, Roberta Corsaro, Dario Rusciano
Summary: MID is a synthetic drug that decreases the availability of L-carnitine, which is important for mitochondria energy generation, thus modulating energy metabolism pathways. It has shown protective effects on blood vessels in models of endothelial dysfunction induced by high glucose or hypertension.
Article
Ophthalmology
Tommaso Rossi, Danilo Iannetta, Vito Romano, Carlo Carlevale, Matteo Forlini, Serena Telani, Aurelio Imburgia, Alessandro Mularoni, Luigi Fontana, Guido Ripandelli
Summary: The study reported the surgical technique and outcomes of using a novel hydrophilic acrylic single-piece intraocular lens. The surgery was successful with significant improvement in vision post-operatively, but there were some intraoperative and post-operative complications that need attention.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Jose J. Echegaray, William E. Smiddy
Summary: This study presents a surgical modification technique for repositioning and scleral fixation of one-piece acrylic intraocular lenses with tapered haptics. The modified technique involves looping the haptic at its proximal, notched junction to the optic using a polypropylene suture and internalizing the suture knot. Three consecutive cases were reviewed and showed adequate lens centration at 3 months of follow-up. The technique provides an alternative to lens exchange.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Natacha B. Junqueira, Leandro J. Chaves, Omero Poli-Neto, Ingrid U. Scott, Rodrigo Jorge
Summary: Scleral fixation with Akreos AO60 and Gore-Tex is generally safe, with significant improvements in visual acuity and endothelial cell density postoperatively. However, complications such as suture exposure were observed in 40% of patients.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Kyu Hwan Jang, Mingui Kong, Byung Gil Moon, Gisung Son
Summary: The study compared the clinical outcomes of sutured scleral fixation and sutureless intrascleral fixation of intraocular lens, and found that the sutureless group had shorter surgery time, faster visual acuity recovery, and lower cylindrical error compared to the sutured group.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Review
Ophthalmology
Matteo Ripa, Romesh Angunawela, Lorenzo Motta
Summary: This study demonstrates that Carlevale IOL implantation can significantly improve BCVA and has a low incidence rate of postoperative complications.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2023)
Article
Ophthalmology
Sirisha Senthil, Raghava Chary, Mohammed Hasnat Ali, Nikhil S. Choudhari, Chandra Sekhar Garudadri
Summary: The study aimed to validate the estimation of Goldmann applanation tonometer (GAT) intraocular pressure (IOP) from scleral Schiotz IOP measurements using a regression model in normal eyes and eyes with type-1 keratoprostheses, showing that the accuracy of the model in assessing IOP was found to be 91%.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Yeji Kim, Eun Young Choi, Christopher Seungkyu Lee, Sung Soo Kim, Suk Ho Byeon
Summary: This study investigated the clinical characteristics of patients with recurrent intraocular lens (IOL) dislocation after scleral-fixated sutured IOL implantation and evaluated the long-term outcomes of scleral re-fixation of IOL. The results showed that younger adults, patients with complicated cataract surgery or aphakic state, and patients with diabetes mellitus (DM) were at a higher risk of IOL re-dislocation. Scleral-fixated sutured IOL in eyes with recurrent IOL dislocation appears to be a safe and effective procedure with a relatively low complication rate.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Engineering, Electrical & Electronic
Ching Hymn Christopher Lee, I. K. Karunaratne, Yifan Wei, Zidong Chen, Iok Tong Chong, Yangfan Yang, Minbin Yu, D. C. C. Lam
Summary: The study demonstrated that continuous intraocular pressure profiles from chipless contact lens sensor can reduce noise, but may still be affected by noise from tears and eyelids in in vivo experiments. The newly designed dual-compliance, dual-element CLS effectively reduces the sensing noise of intraocular pressure.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
