Review
Gastroenterology & Hepatology
Stefan Schreiber, Peter M. Irving, Ala Sharara, Maria Dolores Martin-Arranz, Xavier Hebuterne, Plamen Penchev, Silvio Danese, Prodromos Anthopoulos, Gamar Akhundova-Unadkat, Filip Baert
Summary: This article discusses the background of decreasing recruitment rates for Crohn's disease and ulcerative colitis clinical trials. It identifies key aspects that may improve recruitment rates and proposes potential solutions. The article also summarizes examples of changes implemented during the COVID-19 pandemic.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Nursing
Yue Ma, Ho Yu Cheng, Janet W. H. Sit, Wai Tong Chien
Summary: The smartphone-enhanced nurse-facilitated self-care intervention had positive effects on blood pressure control, anthropometric parameters, and self-care among Chinese hypertensive patients in two community health service centers.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2022)
Article
Multidisciplinary Sciences
Shalika Bohingamu Mudiyanselage, Jo Stevens, Julian Toscano, Mark A. Kotowicz, Christopher L. Steinfort, Robyn Hayles, Jennifer J. Watts
Summary: The study evaluates the cost-effectiveness of a personalised telehealth intervention for managing chronic diseases in the long term. The pilot study compared the costs and effectiveness of telehealth monitoring with usual care and found that the intervention resulted in a significant improvement in health-related quality of life at an additional cost per patient. The study suggests that offering the program to a larger population may be necessary to achieve cost-effectiveness.
Article
Medicine, General & Internal
Anthony Pisani, Kenneth Connor, Kimberly Van Orden, Neil Jordan, Sara Landes, Geoffrey Curran, Michael McDermott, Ashkan Ertefaie, Caroline Kelberman, Seethalakshmi Ramanathan, Jay Carruthers, Kristina Mossgraber, David Goldston
Summary: This study aims to examine the effectiveness of the Attempted Suicide Short Intervention Program (ASSIP) in preventing suicide reattempts in the United States healthcare system. It also investigates the psychological mechanisms of ASSIP based on the Interpersonal Theory of Suicide and explores the potential implementation costs and barriers. The study is a hybrid type 1 effectiveness-implementation randomized controlled trial (RCT) involving 400 adults who have recently attempted suicide.
Article
Medicine, General & Internal
Vita Hagelskjaer, Kristina Tomra Nielsen, Cecilie von Bulow, Lisa Gregersen Oestergaard, Maud Graff, Eva Ejlersen Waehrens
Summary: This study aims to develop and evaluate a complex intervention program for improving the ability of persons with chronic conditions to perform activities of daily living. The study design includes a randomized controlled trial with blinded assessors and investigators, with data collected at multiple time points to evaluate effectiveness, process and cost-effectiveness of the program.
Article
Nutrition & Dietetics
Selina R. Cox, Wladyslawa Czuber-Dochan, Catherine L. Wall, Hazel Clarke, Candice Drysdale, Miranda C. Lomer, James O. Lindsay, Kevin Whelan
Summary: This study aimed to investigate the effectiveness and acceptability of a web resource in enhancing food-related quality of life in newly diagnosed inflammatory bowel disease patients. The results showed that FR-QoL increased more in the web resource group, and IBD distress reduced, while the control group showed opposite results.
Article
Psychology, Multidisciplinary
Ozan Bahcivan, Tania Estape, Jose Gutierrez-Maldonado
Summary: Combining 3rd-wave-therapies with Cognitive-Behavioural-Therapy (CBT) has become more common in recent years. However, the longer sessions required by these therapies can lead to higher drop-out rates for cancer patients. This study developed a shorter 20 min-long mindfulness therapy (MBST) for breast cancer patients and found that it had immediate positive effects on anxiety, depression, self-efficacy, hopefulness, and saturation levels.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Multidisciplinary
Leila Forbes, Susan K. Johnson
Summary: The impact of stress and other psychological variables on Inflammatory Bowel Disease (IBD) prognosis, treatment response, and functional level is significant. Online mindfulness training provides a flexible way for IBD patients to participate, but has a high dropout rate. Supported guidance may help improve the completion rate of the intervention.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Gastroenterology & Hepatology
Palle Bager, Christian Lodberg Hvas, Charlotte Lock Rud, Jens Frederik Dahlerup
Summary: The study demonstrated a significant beneficial effect of high-dose oral thiamine on chronic fatigue in patients with IBD, with good tolerability and symptom improvement. Results from the trial indicated that thiamine was effective in reducing fatigue levels compared to placebo, showing promising outcomes for managing fatigue in IBD patients.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2021)
Article
Geriatrics & Gerontology
Kirsty Sprange, Jules Beresford-Dent, Gail Mountain, Claire Craig, Clare Mason, Katherine Berry, Jessica Wright, Shazmin Majid, Ben Thomas, Cindy L. Cooper
Summary: Understanding intervention delivery as intended, particularly in complex interventions, should be supported by rigorous fidelity assessment. Findings from a study of a community-based psychosocial intervention showed good fidelity to training and delivery at four sites. Despite methodological challenges, tools derived from the fidelity framework proved effective in assessing different aspects of the complex intervention.
Article
Public, Environmental & Occupational Health
Jeannette Weber, Peter Angerer, Lorena Brenner, Jolanda Brezinski, Sophia Chrysanthou, Yesim Erim, Manuel Feisst, Marieke Hansmann, Sinja Hondong, Franziska Maria Kessemeier, Reinhold Kilian, Christina Klose, Volker Koellner, Fiona Kohl, Regina Krisam, Christoph Kroeger, Anja Sander, Ute Beate Schroeder, Ralf Stegmann, Uta Wegewitz, Harald Guendel, Eva Rothermund, Kristin Herrmann
Summary: This study aims to improve mental health of employees with common mental disorders through work-related psychotherapeutic consultation. If successfully implemented and evaluated, it might serve as a role model for the care of employees with common mental disorders in Germany.
Article
Psychology, Clinical
Jilong Yang, Yue Zhao, Yuexin Ji, Jiaxin Ma, Lanyu Li, Xiaoyong Hu
Summary: This study examines the influence of self-affirmation on the academic outcomes of lower-class migrant students and explores the psychological mechanism underlying this phenomenon. The results show that self-affirmation significantly improves the English test performance of lower-class students and this effect is mediated by reducing stereotype threat.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2023)
Article
Medicine, General & Internal
Alexandre Mazeas, Aina Chalabaev, Marine Blond, Bruno Pereira, Martine Duclos
Summary: This study aims to evaluate the effectiveness of a group-based digital intervention grounded on gamification strategies, enhanced by social features, for obese and patients with type 2 diabetes mellitus (T2DM). The study will explore psychological mediators and conduct a cost-utility analysis to assess the potential economic efficiency of the intervention.
Article
Gastroenterology & Hepatology
Ohad Atia, Gemma Pujol-Muncunill, Victor Manuel Navas-Lopez, Esther Orlanski-Meyer, Oren Ledder, Raffi Lev-Tzion, Gili Focht, Eyal Shteyer, Ronen Stein, Marina Aloi, Richard K. Russell, Javier Martin-de-Carpi, Dan Turner
Summary: This study compared the treatment response to biologics in routine practice for children with inflammatory bowel diseases (IBD) who would and would not have been eligible for enrolment in the regulatory randomised controlled trials (RCTs) of the same drug. The results showed that most children initiating biologics for IBD in clinical practice would not have been eligible for the corresponding regulatory RCTs, and the outcomes of ineligible patients were worse than for eligible patients.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Medicine, General & Internal
Bundit Sornpaisarn, Jurgen Rehm, Decha Tamdee, Anon Wisutthananon, Kwaunpanomporn Thummathai, Kanjana Tongtua, Valairux Rutivarnich, Amornrat Suriyalangka, Duangporn Hengboonphan, Shannon Lange
Summary: The ongoing trial aims to evaluate the effectiveness of a community participatory intervention in two subdistricts in Thailand for reducing suicidality symptoms among individuals considered at high risk for suicide and compare the outcomes to two control subdistricts.