Article
Engineering, Multidisciplinary
Yi-Xiang Deng, Hung-Yu Chang, He Li
Summary: Diabetes mellitus, a metabolic disease, has significant impacts on blood hematological properties. However, clinical and experimental studies are unable to directly quantify the contributions of these abnormalities. Computational modeling provides a new approach to investigate the abnormal properties of diabetic blood.
Article
Polymer Science
Amro Othman, Mohammed AlSulaimani, Murtada Saleh Aljawad, Shiv Shankar Sangaru, Muhammad Shahzad Kamal, Mohamed Mahmoud
Summary: The impact of mixing zwitterionic VES with different polymers on the rheology and thermal stability of hydraulic fracturing fluids was investigated. It was found that adding CMC increased viscosity, while adding HEC doubled the viscosity and proved to be more effective. However, HEC reduced system stability at high temperatures. Adding DADMAC polymer increased viscosity and maintained high temperature stability. CaCl2 concentration also affected the rheology of hydraulic fracturing fluids.
Article
Multidisciplinary Sciences
Wei Wei, Yuhuan Li, Myeongsang Lee, Nicholas Andrikopoulos, Sijie Lin, Chunying Chen, David Tai Leong, Feng Ding, Yang Song, Pu Chun Ke
Summary: The production of plastics has played a crucial role in modern society, but the accumulation of plastics in the environment poses a significant threat to environmental sustainability and human health. This study focuses on the biological effects of nanoplastics, specifically anionic polystyrene and poly(methyl methacrylate), and reports that their introduction disrupts the vascular endothelial cadherin junctions. The findings provide important insights into the behavior and impact of nanoplastics, which can guide innovations for a sustainable plastics industry and environmental remediation.
NATURE COMMUNICATIONS
(2022)
Review
Biochemistry & Molecular Biology
Robert J. J. Asaro, Elisabetta Profumo, Brigitta Buttari, Pedro Cabrales
Summary: The presence of red blood cells (RBCs) in the vasculature and their reactivity have sparked discussions about their role(s) in health and disease. These roles are linked to the development of adhesiveness and eventual clearance by macrophages in the spleen. This review explores the mechanisms involved and provides novel perspectives for identifying RBC adhesiveness.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Rodrigo alvarez-Barajas, Antonio A. Cuadri, Francisco J. Navarro, Francisco J. Martinez-Boza, Pedro Partal
Summary: This study explores the use of three native lignin-rich products from industrial bioethanol production and pulping as emulsifiers, finding that emulsification pH strongly affects the stabilization ability of lignins.
Article
Chemistry, Physical
Min Zhang, Wanli Kang, Hongbin Yang, Zhe Li, Xinxin Li, Bobo Zhou, Xin Kang, Menglan Li, Bauyrzhan Sarsenbekuly
Summary: This study investigates the application of erucic acid amidopropyl-betaine (EDAB) and sodium alkyl sulfate (SDS) in constructing worm-like micelle systems for enhanced oil recovery. The results demonstrate that under specific conditions, the EDAB/SDS system exhibits viscoelastic fluid behavior, forming longer linear worm-like micelles and larger network structures. The rheological properties of the EDAB/SDS system are influenced by pH, temperature, and salt concentration.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Applied
Said Elmarhoum, Komla Ako
Summary: The widespread application of polysaccharides is limited by low syneresis impact. Our study demonstrated that the thermodynamic instability of kappa-carrageenan polysaccharide is the origin of syneresis and investigated the effects of KCl salt on critical concentration and LCCT. The difference between Tg and LCCT serves as the thermomotive force behind the syneresis of many colloidal gels.
CARBOHYDRATE POLYMERS
(2021)
Article
Engineering, Chemical
Chao Wang, Wensheng Zhang, Chunhua Zhang, Huifang Xu, Lijia Liu, Chunhong Zhang
Summary: In this study, a membrane with enhanced permeability was constructed using derivatives of natural products, and a highly negatively charged surface was achieved to exhibit excellent separation performance and anti-pollution capacity.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Agriculture, Multidisciplinary
Julia Jianwei Tan, Natalie Gjerde, Alessandra Del Giudice, Kenneth D. Knudsen, Luciano Galantini, Guanqun Du, Karin Schillen, Sverre Arne Sande, Bo Nystrom
Summary: This study investigates the interactions between cationic hydroxyethyl cellulose (catHEC) and sodium deoxycholate (NaDC) or sodium cholate (NaC). It is found that there are strong interactions between catHEC and NaDC, while the interactions with NaC are weak. This difference may be due to the ability of NaDC to form more connections and entanglements.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Hematology
Ellen G. Driever, Iain Muntz, Vishal Patel, Jelle Adelmeijer, William Bernal, Gijsje H. Koenderink, Ton Lisman
Summary: This study found that clots from patients with ACLF have weak mechanical properties despite unaltered fibrin fiber density. Previous experiments may have erroneously concluded that ACLF clots are prothrombotic as fibrinogen hypersialylation leads to underestimation of clot permeability in this setting, presumably due to enhanced water retention.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Chemistry, Physical
V. S. Molchanov, A. Kuklin, A. S. Orekhov, N. A. Arkharova, O. E. Philippova
Summary: Rheometry, small-angle neutron scattering, and cryo-transmission electron microscopy were used to investigate the structure and properties of mixed wormlike micelles (WLMs) of zwitterionic and anionic surfactants. The study found that the transition of linear micelles into branched micelles at increasing surfactant concentration leads to a drop in viscosity and approaches the system to the behavior of Maxwell fluid with a single relaxation time, which strongly affects the rheological properties and can be exploited in various applications of zwitterionic surfactants.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Review
Physiology
Sebastian Himbert, Maikel C. Rheinstadter
Summary: Red blood cells, the most abundant cell type in the human body, have a simple structure and are both flexible and resistant to shear stress. The composition and organization of their outer shell play a crucial role in their mechanical properties. Current research indicates that the structure of the cell membrane is patchy, with liquid ordered and disordered lipid and peptide domains. Contrary to previous beliefs, the membrane is surprisingly soft, potentially due to the interaction between polyunsaturated lipids and cholesterol.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Engineering, Chemical
Marco E. Rosti, Parisa Mirbod, Luca Brandt
Summary: The study investigates the influence of isotropic porous walls on a plane Couette flow with spherical and rigid particles. It is found that the porous walls lead to a progressive decrease in the suspension effective viscosity as the wall permeability increases. This is due to the weakening of the wall-blocking effect and the appearance of slip velocity, which reduces the shear rate and dampens particle rotation and velocity fluctuations.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Polymer Science
Leonid Iliasov, Andrey Shibaev, Irina Panova, Petr Kushchev, Olga Philippova, Alexander Yaroslavov
Summary: Six cross-linked copolymers were synthesized with sodium acrylate, N-acrylamide, starch fragments, and a cross-linker, potentially suitable for use in agriculture as superabsorbents. The copolymers formed hydrogel particles when swelled in a pH 6.5 aqueous buffer solution. The cross-linking degree controlled the swelling pressure of hydrogels and water-retaining properties of solid substrates with embedded hydrogels, providing important insights for the synthesis and optimization of polymeric superabsorbents.
Article
Biotechnology & Applied Microbiology
Swe Soe Maung Ye, Sangho Kim
Summary: Red blood cell aggregation occurs under low flow conditions, and plasma-mediated aggregation involves cross-bridging mechanisms. Fibrinogen plays a dominant role in promoting aggregate formation, and specific and non-specific cross-bridging have different effects on aggregation and disaggregation.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Domenico Iacopetta, Noemi Baldino, Anna Caruso, Valentina Perri, Francesca Romana Lupi, Bruno de Cindio, Domenico Gabriele, Maria Stefania Sinicropi
Summary: The aim of this study was to evaluate the extraction of nutraceuticals from cactus pear using supercritical fluid technology. Different sample preparations were found to affect the extraction efficiency and selectivity of polyphenols. High pressure during extraction resulted in a drastic reduction of both quantity and quality of polyphenols.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
M. G. De Paola, D. Mammolenti, F. R. Lupi, M. P. De Santo, D. Gabriele, V Calabro
Summary: Potato starch-based films produced by tape-casting were studied in terms of stability and plasticizing effect of glycerol. The addition of glycerol improved the stability and plasticity of the films, as confirmed by thermal behavior, microstructural investigation, and FT-IR spectroscopy. Additionally, atomic force microscopy showed a uniform surface with increased glycerol content.
Article
Chemistry, Applied
Olga Mileti, Noemi Baldino, Jose Antonio Carmona, Francesca Romana Lupi, Jose Munoz, Domenico Gabriele
Summary: This study investigated the surface properties of three different proteins extracted from vegetable sources, namely soy, hemp, and brown rice seeds. The findings suggest that these proteins exhibit excellent interfacial properties, making them suitable for use in food multiphase systems without the need for surfactants or animal proteins. Among the three proteins, brown rice protein yields stronger interfacial layers, soy protein has a greater impact on structuring the interface, and hemp protein displays intermediate properties.
FOOD HYDROCOLLOIDS
(2022)
Article
Biochemistry & Molecular Biology
Mariacristina Filice, Rosa Mazza, Sandra Imbrogno, Olga Mileti, Noemi Baldino, Amilcare Barca, Gianmarco Del Vecchio, Tiziano Verri, Alfonsina Gattuso, Maria Carmela Cerra
Summary: This study demonstrates for the first time the presence of an ACE2/Alamandine axis in goldfish and shows that it plays a role in modulating myocardial contractility through the NOS/NO system.
Article
Biophysics
Olga Mileti, Noemi Baldino, Francesca Romana Lupi, Domenico Gabriele
Summary: Proteins play a crucial role in forming and stabilizing multiphase systems by reducing interfacial tension and promoting viscoelastic layers. However, there is a lack of research on the surface activity and emulsifying ability of plant-based proteins. This study investigates the interfacial properties of soy, hemp, and brown rice proteins with commercial sunflower oil for potential use in various food applications. The results demonstrate that all tested proteins can form strong viscoelastic layers, with brown rice protein being particularly effective in reducing interfacial tension. Hemp protein shows promise with intermediate interfacial tensions and strong viscoelastic layers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Noemi Baldino, Ilaria Carnevale, Olga Mileti, Donatella Aiello, Francesca R. Lupi, Anna Napoli, Domenico Gabriele
Summary: Industrial hemp, with its rich protein and oil content, has gained attention as a new raw material in the food industry. A study on the extraction process of hemp oil using supercritical CO2 and ultrasounds revealed that it can be a high-quality alternative to traditional animal sources. The waste from extraction can be utilized in food formulations, and a stable emulsion can be formed by adding thickening polysaccharides. This research offers possibilities for innovative food products with high nutritional value.
APPLIED SCIENCES-BASEL
(2022)
Article
Biochemistry & Molecular Biology
Mariangela Marrelli, Francesca Giordano, Maria Rosaria Perri, Valentina Amodeo, Noemi Baldino, Carmine Lupia, Dimitar Uzunov, Vincenzo Musolino, Filomena Conforti, Maria Luisa Panno
Summary: The study assessed the photocytotoxic activity of Prangos ferulacea Lindl. (synonym of C. ferulacea (L.) Calest.), a plant previously considered a Cachrys species but now classified as Prangos genus. Three different extraction techniques were used, and the obtained extracts were compared for their phytochemical content and photobiological properties on human melanoma cells. P. ferulacea extracts showed concentration-dependent impact on cell viability, with the sample obtained through supercritical CO2 extraction showing the highest activity. This research highlights the presence of interesting photoactive compounds in P. ferulacea and its potential for cancer photochemotherapy.
Article
Food Science & Technology
Elisabetta Bruno, Francesca Romana Lupi, Domenico Mammolenti, Olga Mileti, Noemi Baldino, Domenico Gabriele
Summary: This study investigated the rheological and microscopic properties of O/W emulgels with citrus fiber as the gelling agent. A rheological model was proposed to predict the characteristics of the emulgels. The results showed that the properties of the emulgels were strongly influenced by the fiber concentration and process conditions.
Review
Biochemistry & Molecular Biology
Domenico Iacopetta, Jessica Ceramella, Noemi Baldino, Maria Stefania Sinicropi, Alessia Catalano
Summary: Breast cancer is one of the most common and deadly cancers among women worldwide. Surgery, radiotherapy, and chemotherapy are the main treatments, but chemotherapy often fails due to side effects and damage to healthy tissues. New studies are needed to find new therapies and strategies for aggressive and metastatic breast cancers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Olga Mileti, Noemi Baldino, Francesco Filice, Francesca R. Lupi, Maria Stefania Sinicropi, Domenico Gabriele
Summary: This study investigated the extraction process of waste using solvent and supercritical CO2 extraction and utilized the obtained anthocyanins for starch-based food film formulations. The addition of anthocyanins improved the structuring and mechanical properties of the films, making them suitable for applications like dipping using coverage methods. The packaging also exhibited attractiveness and pH-sensitivity.
Article
Biochemistry & Molecular Biology
Teresa Pasqua, Carmine Rocca, Francesca Romana Lupi, Noemi Baldino, Daniela Amelio, Ortensia Ilaria Parisi, Maria Concetta Granieri, Anna De Bartolo, Arturo Lauria, Marco Dattilo, Ida Daniela Perrotta, Francesco Puoci, Maria Carmela Cerra, Domenico Gabriele, Tommaso Angelone