4.7 Article

Chronic West Nile virus infection in kea (Nestor notabilis)

Journal

VETERINARY MICROBIOLOGY
Volume 183, Issue -, Pages 135-139

Publisher

ELSEVIER
DOI: 10.1016/j.vetmic.2015.12.012

Keywords

West Nile virus; WNV; Lineage 2; Kea; Nestor notabilis; Psittaciformes; Persistent infection; Austria

Funding

  1. Austrian Science Foundation FWF [P19087-B17]
  2. European Commission [FP7-HEALTH-2010.2.33-3/2261391, FP7-HEALTH-2010/261504]
  3. Austrian Science Fund (FWF) [P19087] Funding Source: Austrian Science Fund (FWF)

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Six kea (Nestor notabilis) in human care, naturally infected with West Nile virus (WNV) lineage 2 in Vienna, Austria, in 2008, developed mild to fatal neurological signs. WNV RNA persisted and the virus evolved in the birds' brains, as demonstrated by (phylo)genetic analyses of the complete viral genomes detected in kea euthanized between 2009 and 2014. WNV antibodies persisted in the birds, too. Chronic WNV infection in the brain might contribute to the circulation of the virus through oral transmission to. predatory birds. (C) 2015 Elsevier B.V. All rights reserved.

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