Journal
VASCULAR PHARMACOLOGY
Volume 81, Issue -, Pages 15-21Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.vph.2016.04.001
Keywords
MicroRNA; Troponin; Biomarker; Acute coronary syndrome
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Funding
- Association for the Promotion of Research in Arteriosclerosis, Thrombosis and Vascular Biology (ATVB)
- Ludwig Boltzmann Cluster for Cardiovascular Research, Vienna, Austria
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Coronary artery disease (CAD) and its complications remain the most common cause of death worldwide. Cardiac troponins (cTn) are standard biomarkers used today for diagnosis and risk stratification of myocardial infarction (MI). Increasing efforts are made to develop additional, new biomarkers for more effective and safe rule-in and rule-out of MI patients at the emergency department. During the past decade, microRNAs (miRNAs) have emerged as new, potential diagnostic biomarkers in several diseases, including MI. In this review, we aimed to summarize some of the prominent studies in the field, and discuss the potential value of miRNAs in the diagnosis of MI. (C) 2016 Elsevier Inc. All rights reserved.
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