Article
Urology & Nephrology
Avery R. Wolfe, Nicolas M. Ortiz, Adam S. Baumgarten, Maia E. VanDyke, Mary L. West, Benjamin M. Dropkin, Gregory A. Joice, Sarah C. Sanders, Steven J. Hudak, Allen F. Morey
Summary: Low serum testosterone (LT) is an independent risk factor for AUS cuff erosion. Men with LT are more likely to present with cuff erosion, but there is no difference in time to erosion.
NEUROUROLOGY AND URODYNAMICS
(2021)
Article
Andrology
Luke A. Shumaker, Tyler R. Compher, John P. Selph
Summary: The artificial urinary sphincter (AUS) has been a successful treatment for post-prostatectomy incontinence in men. However, cuff erosion is a troublesome complication. This study suggests that urgent explantation may not be necessary in asymptomatic cases of cuff erosion.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2023)
Article
Andrology
Luke A. Shumaker, Tyler R. Compher, John P. Selph
Summary: The artificial urinary sphincter (AUS) is commonly used to treat post-prostatectomy incontinence in men, with high success rates. However, cuff erosion is a troublesome complication that requires device removal. The timing and need for explantation in asymptomatic cuff erosion remains unclear.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2023)
Article
Urology & Nephrology
Kevin Krughoff, Brent D. Nose, Andrew C. Peterson
Summary: Cuff downsizing improves continence and patient satisfaction in cases of sub-cuff atrophy.
JOURNAL OF UROLOGY
(2023)
Article
Medicine, General & Internal
Tomasz Szopinski, Iwona Sudol-Szopinska, Anna K. Czech, Jerzy Gasowski, Piotr L. Chlosta
Summary: This study evaluated the treatment outcomes of male urinary incontinence using an artificial urinary sphincter (AUS) with a cuff placed around the prostatic urethra. The analysis showed that cuff placement around the prostatic urethra resulted in better continence and fewer complications.
ARCHIVES OF MEDICAL SCIENCE
(2022)
Article
Urology & Nephrology
Nathan A. Chertack, Kelly M. Caldwell, Gregory A. Joice, Mehraban Kavoussi, Benjamin M. Dropkin, Nicolas M. Ortiz, Adam S. Baumgarten, Nabeel A. Shakir, Sarah C. Sanders, Steven J. Hudak, Allen F. Morey
Summary: Lower urinary tract complications are common after AUS cuff erosion, with 30% of patients experiencing LUTC and 35% requiring permanent UD. Patients with larger erosions are more likely to undergo UD and reach this end-stage condition earlier compared to patients with small erosions. Secondary AUS placement is common but may lead to repeat erosions in some cases.
NEUROUROLOGY AND URODYNAMICS
(2022)
Article
Urology & Nephrology
Linley Diao, Samantha W. Nealon, Gianpaolo P. Carpinito, Shervin Badkhshan, Avery R. Wolfe, Benjamin M. Dropkin, Sarah C. Sanders, Steven J. Hudak, Allen F. Morey
Summary: Artificial urinary sphincter (AUS) cuff erosion commonly presents with scrotal inflammatory symptoms, with obstructive voiding symptoms and worsening incontinence also being common. Patients with scrotal inflammation or obstructive symptoms tend to present earlier than those with worsening incontinence. Men who suffered erosion had a higher prevalence of pelvic radiation compared to the non-erosion control group.
INTERNATIONAL BRAZ J UROL
(2022)
Article
Andrology
Kevin C. Lewis, Scott D. Lundy, Kenneth Angermeier
Summary: This report describes two cases of AUS cuff intraurethral migration associated with calcification leading to urethral obstruction. Post-surgery assessment of the urethra and critical examinations before considering AUS replacement are essential.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2022)
Article
Surgery
Katharina Kuhlencord, Roland Dahlem, Malte W. Vetterlein, Raisa S. Abrams-Pompe, Valentin Maurer, Christian P. Meyer, Silke Riechardt, Margit Fisch, Tim A. Ludwig, Phillip Marks
Summary: The study aims to describe a standardized less invasive approach for patients with artificial urinary sphincter (AUS) explantation due to cuff erosion and analyze success rates and urethral stricture rates. The results showed a considerably low stricture formation and suggested that primary urethroplasty or delay in salvage stress urinary incontinence (SUI) treatment may not be necessary.
FRONTIERS IN SURGERY
(2022)
Article
Urology & Nephrology
Samuel Otis-Chapados, Thomas de los Reyes, Ahmad Mousa, Gagan Fervaha, Sidney B. Radomski
Summary: This study retrospectively reviewed AUS implants performed from 1991 to 2021 at the institution to compare the impact of AUS cuff sizes on urinary incontinence. The results showed that at 1 year post-AUS surgery, both groups had similar pad use. The erosion rate was higher in the group with cuff sizes <= 4.5 cm, but this was not statistically significant. Therefore, in cases with a history of radiation, it is advisable to choose a larger cuff size during AUS implantation.
CANADIAN JOURNAL OF UROLOGY
(2023)
Article
Biochemistry & Molecular Biology
Austin Sigler, Jiandong Wu, Annalise Pfaff, Olajide Adetunji, Paul Nam, Donald James, Casey Burton, Honglan Shi
Summary: Repeated exposure to low-level blasts can cause biological changes similar to mild traumatic brain injury. This study aimed to find potential small molecule biomarkers of brain injury during repeated blast exposure. The study evaluated ten small molecule metabolites and found that urinary levels of homovanillic acid, linoleic acid, and glutamate, as well as serum levels of N-acetylaspartic acid, were significantly altered after repeated blast exposure. The results suggest that measuring these metabolites could help identify individuals at risk of TBI.
Article
Urology & Nephrology
Samuel Otis-Chapados, Justin Kim, Sidney B. Radomski
Summary: This study aimed to determine which size of catheters/scopes can safely pass through different cuff sizes of AUS, using measurements of cuff space and urethral thickness in male patients. Specific recommendations were made for different cuff sizes based on the findings.
NEUROUROLOGY AND URODYNAMICS
(2022)
Review
Engineering, Biomedical
Minghui Wang, Yucheng Liao, Yunlong Liu, Wei Zhou, Hongliu Yu
Summary: This study aims to design an ideal artificial urinary sphincter and discusses the deficiencies of existing designs. It focuses on individual improvement, engineering design elements, and optimization of the manufacturing process. The ultimate goal is to improve the quality of life for patients, but further research is needed to support this approach.
Article
Urology & Nephrology
Thibault Tricard, A. Schirmann, P. Munier, A. Schroeder, C. Saussine
Summary: The study reported the outcomes of artificial urinary sphincter (AUS) implantation in women with neurological stress urinary incontinence (SUI) over a 3 to 20 year follow-up period. The majority of patients achieved long-term continence after the surgery.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Endocrinology & Metabolism
Jona Elings Knutsson, Alexander Andersson, Lasse Vestli Baekken, Anton Pohanka, Lena Ekstrom, Angelica Linden Hirschberg
Summary: Exogenous testosterone administration in young healthy women resulted in increased levels of testosterone and dihydrotestosterone in serum, while sex hormone-binding globulin and 17-hydroxyprogesterone decreased. Urine analysis showed increases in testosterone and 5 alpha-androstanediol. Serum total testosterone levels could be a potential marker for detecting doping in women, as the testosterone/epitestosterone ratio alone may not be sufficient.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)