Neuropilin-1 (NRP-1)/GIPC1 pathway mediates glioma progression

Mechanisms regulating glioma invasion

(2015) Ivy Paw et al.   CANCER LETTERS

RAS/ERK Signaling Controls Proneural Genetic Programs in Cortical Development and Gliomagenesis

(2014) S. Li et al.   JOURNAL OF NEUROSCIENCE

A neurocentric perspective on glioma invasion

(2014) Vishnu Anand Cuddapah et al.   NATURE REVIEWS NEUROSCIENCE

Neuropilin-1 Promotes Epithelial-to-Mesenchymal Transition by Stimulating Nuclear Factor-Kappa B and Is Associated with Poor Prognosis in Human Oral Squamous Cell Carcinoma

(2014) Weiming Chu et al.   PLoS One

Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma

(2013) Matija Snuderl et al.   CELL

The cytoplasmic domain of neuropilin-1 regulates focal adhesion turnover

(2013) Himabindu Reddy Seerapu et al.   FEBS LETTERS

Inhibitory Effect of Neuropilin-1 Monoclonal Antibody (NRP-1 MAb) on Glioma Tumor in Mice

(2013) Lukui Chen et al.   Journal of Biomedical Nanotechnology

The Expression and Significance of Neuropilin-1 (NRP-1) on Glioma Cell Lines and Glioma Tissues

(2013) Lukui Chen et al.   Journal of Biomedical Nanotechnology

Emerging Roles of microRNA in Modulating Cell-Death Processes in Malignant Glioma

(2013) Silvia Palumbo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting Mutant KRAS for Anticancer Therapeutics: A Review of Novel Small Molecule Modulators

(2013) Yuanxiang Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting the Ras–ERK pathway in pancreatic adenocarcinoma

(2012) Cindy Neuzillet et al.   CANCER AND METASTASIS REVIEWS

Analysis of Tumor Metabolism Reveals Mitochondrial Glucose Oxidation in Genetically Diverse Human Glioblastomas in the Mouse Brain In Vivo

(2012) Isaac Marin-Valencia et al.   Cell Metabolism

p130Cas: A key signalling node in health and disease

(2012) Angela Barrett et al.   CELLULAR SIGNALLING

Autocrine VEGF–VEGFR2–Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

(2012) Petra Hamerlik et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The PDZ Protein GIPC Regulates Trafficking of the LPA1 Receptor from APPL Signaling Endosomes and Attenuates the Cell’s Response to LPA

(2012) Tal Varsano et al.   PLoS One

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas

(2011) Caroline Pellet-Many et al.   BIOCHEMICAL JOURNAL

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

Targeting apoptosis pathways in glioblastoma

(2011) Günter Eisele et al.   CANCER LETTERS

Exciting New Advances in Neuro-Oncology: The Avenue to a Cure for Malignant Glioma

(2010) E. G. Van Meir et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

GIPC mediates the generation of reactive oxygen species and the regulation of cancer cell proliferation by insulin-like growth factor-1/IGF-1R signaling

(2010) Ji Seung Choi et al.   CANCER LETTERS

Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta

(2010) Yelena Glinka et al.   CARCINOGENESIS

RGS-GAIP-Interacting Protein Controls Breast Cancer Progression

(2010) L. Wang et al.   MOLECULAR CANCER RESEARCH

Targeting GIPC/Synectin in Pancreatic Cancer Inhibits Tumor Growth

(2009) M. H. Muders et al.   CLINICAL CANCER RESEARCH

Neuropilin-1/GIPC1 Signaling Regulates α5β1 Integrin Traffic and Function in Endothelial Cells

(2009) Donatella Valdembri et al.   PLOS BIOLOGY

Neuropilins: structure, function and role in disease

(2008) Caroline Pellet-Many et al.   BIOCHEMICAL JOURNAL

Native human autoantibodies targeting GIPC1 identify differential expression in malignant tumors of the breast and ovary

(2008) Victoria Yavelsky et al.   BMC CANCER

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway

(2008) Paul Frankel et al.   EMBO REPORTS

Neuropilin-1-VEGFR-2 Complexing Requires the PDZ-binding Domain of Neuropilin-1

(2008) Claudia Prahst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II Study of Imatinib in Patients With Recurrent Gliomas of Various Histologies: A European Organisation for Research and Treatment of Cancer Brain Tumor Group Study

(2008) Eric Raymond et al.   JOURNAL OF CLINICAL ONCOLOGY