Article
Oncology
Xin Xu, Yida Lu, Youliang Wu, Mingliang Wang, Xiaodong Wang, Huizhen Wang, Bo Chen, Yongxiang Li
Summary: This study identified a novel seven-IRGs risk signature for individualized survival prediction of male GC patients. The expression of these seven genes could reflect the status of the tumor immune microenvironment. The established risk signature model showed excellent predictive performance in evaluating the prognosis of individual male GC patients.
CANCER CELL INTERNATIONAL
(2021)
Article
Oncology
Sun Young Rha, Geoffrey Y. Ku, Hyo Song Kim, Hyun Cheol Chung, Fatemeh Ghazanfari Amlashi, Dipen Maheshbhai Maru, Carly A. Fein, Laura H. Tang, Wei Zhou, Ting Wu, Senaka A. Peter, David P. Kelsen, Jaffer A. Ajani
Summary: This retrospective study found that PD-L1 expression is not associated with overall survival in gastric cancer patients, and the prevalence of PD-L1 and its association with survival are similar between Korean and US patients.
Article
Oncology
Yuan Zhou, Changming Lin, Lian Zhu, Rentao Zhang, Lei Cheng, Yuanyuan Chang
Summary: This study established predictive models and a scoring system to predict the survival rate of prostate cancer patients. These tools can help clinicians individually assess the survival status of patients and contribute to clinical decisions.
Article
Cell Biology
Bo Xiao, Liyan Liu, Zhuoyuan Chen, Aoyu Li, Yu Xia, Pingxiao Wang, Cheng Xiang, Yi Zeng, Hui Li
Summary: This study identified a novel prognostic marker based on stem cell-related genes for osteosarcoma patients, independent of other clinical traits. The marker was validated to be significant in predicting survival rate and providing potential therapeutic targets. The research suggests that the expression level of stem cell-related genes could serve as valuable prognostic markers and therapeutic targets for osteosarcoma.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Genetics & Heredity
Weiyu Dai, Yizhi Xiao, Weimei Tang, Jiaying Li, Linjie Hong, Jieming Zhang, Miaomiao Pei, Jianjiao Lin, Side Liu, Xiaosheng Wu, Li Xiang, Jide Wang
Summary: A novel EMT-related gene signature was established for predicting overall survival in gastric cancer, showing good performance in both internal and external validations. The signature was proven to be an independent prognostic factor and presented better predictive accuracy and clinical usefulness compared to models without risk score. The study suggested that high expression of the five EMT-related genes may be found in human GC cell lines, with potential involvement of focal adhesion and ECM-receptor interaction pathways.
FRONTIERS IN GENETICS
(2021)
Article
Oncology
Caihong Zheng, Chengbin Fu, Yahui Wen, Jiameng Liu, Shunguo Lin, Hui Han, Zhonghua Han, Chunsen Xu
Summary: A nomogram was developed and validated to predict the overall survival of patients with metaplastic breast cancer (MBC). MBC patients had worse clinical prognosis compared to infiltrating ductal carcinoma. This nomogram can assist clinicians in making more accurate individualized survival analyses.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Bartlomiej Barczynski, Karolina Fraszczak, Artur Wnorowski, Jan Kotarski
Summary: Endometrial cancer is a leading cause of female genital tract malignancies, and our study assesses the influence of clinicopathological features on overall survival. We found that menopause status and related characteristics strongly correlate with patients' survival. Further research is needed to improve personalized care for cancer patients.
Article
Surgery
Ho-Jung Shin, Sang-Yong Son, Bo Wang, Chul Kyu Roh, Hoon Hur, Sang-Uk Han
Summary: This study compared the long-term outcomes of robotic and LG approaches in patients with gastric cancer. The results showed that after balancing covariates, there were no significant differences in long-term survival and recurrence-free survival between the two surgical methods, and robotic gastrectomy showed advantages in reducing blood loss.
Article
Oncology
Mingming Zhang, Xiaoru Hu, Ye Kang, Wanfeng Xu, Xianghong Yang
Summary: The study found that fasting blood glucose levels are not significantly associated with overall survival of patients with pancreatic cancer, with only CA199 > 1000 being independently correlated with survival. The median survival in the normal glucose group was 20.5 months, while in the high blood glucose group it was 14.2 months, with no significant difference between the two groups.
Article
Medicine, General & Internal
Peng Wen, Jiao Wen, Xiaolong Huang, Fengze Wang
Summary: This study successfully constructed two nomogram models to predict overall survival (OS) and cancer-specific survival (CSS) of bladder cancer patients, which have clinical significance.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Guoqiao Zheng, Subhayan Chattopadhyay, Kristina Sundquist, Jan Sundquist, Asta Foersti, Akseli Hemminki, Kari Hemminki
Summary: Favorable survival in malignant cutaneous melanoma has led to an increase in the likelihood of developing second primary cancer. A significant proportion of patients developed other SPCs, with higher survival rates observed for women compared to men. Time-dependent analysis showed increased hazard ratios for fatal cancer types, but SPC-specific hazard ratios remained uniform regardless of when the SPC was diagnosed. Additional efforts are needed to improve survival rates for patients with various types of SPCs.
Article
Oncology
Zhuolin Li, Yao Lin, Bizhen Cheng, Qiaoxin Zhang, Yingmu Cai
Summary: This study evaluated prognostic factors for cervical squamous cell carcinoma (CSCC) and developed personalized risk assessment nomograms to predict overall survival (OS) and cancer-specific survival (CSS) in CSCC patients. The nomograms showed good performance in prognostic prediction and could be used as an effective tool for evaluating the prognosis of CSCC patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Fangxu Yin, Song Wang, Chong Hou, Yiyuan Zhang, Zhenlin Yang, Xiaohong Wang
Summary: This study developed two accurate prediction models for survival outcomes in locally advanced breast cancer patients, which were more accurate than conventional TNM staging. These models can guide clinical decision-making and treatment planning for these patients.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Nutrition & Dietetics
B. S. Te Fang, Yang Gong, Yue Wang
Summary: Gastric cancer is a common and deadly cancer worldwide. Recent studies have shown inconsistent conclusions about the predictive power of myosteatosis for overall survival in patients with gastric cancer. This meta-analysis aims to systematically quantify the predictive power of myosteatosis for overall survival in the gastric cancer setting.
Article
Surgery
Tomoyuki Nagata, Yuki Adachi, Akihiro Taniguchi, Yu Kimura, Daisuke Iitaka, George Iwata, Nobuki Yamaoka
Summary: This study investigated the impact of postoperative complications on the prognosis of patients who underwent gastrectomy. The results showed that postoperative complications were associated with both gastric cancer-specific death and death from other causes. The major complications were classified into C-com and N-com groups based on their prognostic impact on cancer-specific survival and non-specific survival, respectively. Different postoperative complications worsened patient prognosis after gastrectomy in different ways, highlighting the importance of improved treatment strategies for different complication types.
ASIAN JOURNAL OF SURGERY
(2023)