Article
Computer Science, Information Systems
Rachel L. Richesson, Keith S. Marsolo, Brian J. Douthit, Karen Staman, P. Michael Ho, Dana Dailey, Andrew D. Boyd, Kathleen M. McTigue, Miriam O. Ezenwa, Judith M. Schlaeger, Crystal L. Patil, Keturah R. Faurot, Leah Tuzzio, Eric B. Larson, Emily C. O'Brien, Christina K. Zigler, Joshua R. Lakin, Alice R. Pressman, Jordan M. Braciszewski, Corita Grudzen, Guilherme Del Fiol
Summary: The study identified 21 challenges related to EHR systems in pragmatic research, falling into 6 broad themes, and formulated 6 prerequisites for conducting pragmatic clinical trials.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2021)
Article
Computer Science, Information Systems
Andrew D. Boyd, Rosa Gonzalez-Guarda, Katharine Lawrence, Crystal L. Patil, Miriam O. Ezenwa, Emily C. O'Brien, Hyung Paek, Jordan M. Braciszewski, Oluwaseun Adeyemi, Allison M. Cuthel, Juanita E. Darby, Christina K. Zigler, P. Michael Ho, Keturah R. Faurot, Karen L. Staman, Jonathan W. Leigh, Dana L. Dailey, Andrea Cheville, Guilherme Del Fiol, Mitchell R. Knisely, Corita R. Grudzen, Keith Marsolo, Rachel L. Richesson, Judith M. Schlaeger
Summary: Embedded pragmatic clinical trials (ePCTs) play a vital role in addressing population health problems by utilizing electronic health record (EHR) systems to increase the speed and volume of relevant research. However, the growing number of ePCTs using EHR-derived data increases the risk of biases due to differences in data capture and access to care, perpetuating health inequalities. This article identifies 3 challenges - incomplete data on social determinants of health, lack of representation of vulnerable populations, and data loss due to variable technology use - that exacerbate bias when working with EHR data and provides recommendations and examples to actively mitigate bias.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Article
Medicine, Research & Experimental
Emily C. O'Brien, Jeremy Sugarman, Kevin P. Weinfurt, Eric B. Larson, Patrick J. Heagerty, Adrian F. Hernandez, Lesley H. Curtis
Summary: The COVID-19 pandemic has had a significant impact on pragmatic clinical trials, affecting healthcare operations and social distancing. Trial delays have introduced statistical challenges and necessitated changes in data collection strategies or interventions. Stakeholder-driven approaches have been used to adapt interventions, resulting in benefits such as expanded outreach capabilities and the study of virtual intervention delivery.
Article
Health Care Sciences & Services
Luis F. Ganoza, Jennifer Villani, Carrie N. Klabunde
Summary: This study analyzes the prevention health care delivery research grant portfolio supported by the National Institutes of Health (NIH). The findings show that health care delivery research comprises a modest portion of the NIH prevention research portfolio and is mostly focused on access and quality of care. The most frequently studied health topics in this portfolio are human immunodeficiency virus/acquired immune deficiency syndrome, cancer, and substance use.
Article
Emergency Medicine
Jeremy Brown
Summary: The study found an increase in NIH support for clinical emergency care research over a 4-year period, but there is still a low number of grant submissions for this field compared to similar disciplines.
ANNALS OF EMERGENCY MEDICINE
(2021)
Article
Surgery
Monica Fahrenholtz, Daniel R. Salvati, Leanne B. Scott, Allan M. Goldstein, Sundeep G. Keswani
Summary: In the process of developing an application for funding, it is crucial to give attention to both the scientific aspect and the budget. A well-planned budget demonstrates an understanding of the project's needs and realistic cost expectations, increasing the likelihood of receiving the requested budget from funding agencies.
Article
Health Care Sciences & Services
Marcel E. Salive, Jerry Suls, Tilda Farhat, Carrie N. Klabunde
Summary: This study presents a research framework for multimorbidity, addressing gaps in the literature related to potential causes, interactions, and outcomes. By focusing on a patient-centered approach and improving study design and outcome measurement, multimorbidity research can be advanced to better understand and treat the co-occurrence of chronic diseases.
Article
Medicine, General & Internal
Feyisope R. Eweje, Suzie Byun, Rajat Chandra, Fengling Hu, Ihab Kamel, Paul Zhang, Zhicheng Jiao, Harrison X. Bai
Summary: This study examines the potential translational impact of medical AI and identifies the application topics with the highest estimated impact. The findings suggest that interpersonal communication technologies and population genetics have the greatest translatability, while biochemical analysis has lower translatability.
Article
Public, Environmental & Occupational Health
Elizabeth Barr, Ronna Popkin, Erik Roodzant, Beth Jaworski, Sarah M. Temkin
Summary: Gender is a social and structural variable that has profound impacts on health. More research is needed to differentiate the effects of gender from sex and other biological variables. The National Institutes of Health envisions integrating gender and/or sex influences into health research, but currently, the research is limited to a few conditions and locations. There are opportunities to advance interdisciplinary research on the health impacts of gender and other variables by incorporating best practices from established disciplines.
TRANSLATIONAL BEHAVIORAL MEDICINE
(2023)
Article
Oncology
Steven S. Coughlin, Jie Chen, Jorge E. Cortes
Summary: Analysis of data from the NIH All of Us Research Program reveals that a minority of cancer survivors faced financial difficulties in paying for healthcare in the past 12 months. Of particular concern are minorities such as African American and Hispanic cancer survivors as well as those who are low income.
Editorial Material
Psychology, Applied
LaVerne Brown, Barbara Cohen, Rebecca Costello, Olga Brazhnik, Zorina Galis
Summary: The NIH has gathered input on resilience in the context of human health and biomedical sciences to accelerate advances in health maintenance. Resilience refers to a system's ability to recover, grow, adapt, or resist challenges or stressors. The various scientific domains provide frameworks for studying resilience and advancing health maintenance.
Article
Clinical Neurology
Luke G. F. Smith, E. Antonio Chiocca, Gregory J. Zipfel, Adam G. F. Smith, Michael W. Groff, Regis W. Haid, Russell R. Lonser
Summary: The study assessed the success of Neurosurgery Research and Education Foundation (NREF) awardees in obtaining subsequent National Institutes of Health (NIH) funding. It was found that a significant portion of NREF awardees went on to receive NIH funding, indicating the importance and effectiveness of NREF in supporting neurosurgeon-scientists.
JOURNAL OF NEUROSURGERY
(2022)
Article
Biology
Michael S. Lauer, Joy Wang, Deepshikha Roychowdhury
Summary: We analyzed changes in total costs of National Institutes of Health (NIH) awarded Research Project Grants (RPGs) from 1998 to 2021. There were changes in both nominal and real costs, with real costs showing a decrease and stability after the doubling of NIH budget. These changes in real costs are largely explained by changes in the composition of the NIH-grant portfolio.
Article
Medicine, General & Internal
Kelly M. Gillen, Daniel M. Markowitz, Patricia Long, Adriel Villegas-Estrada, Eileen Chang, Ajay Gupta
Summary: This study aims to determine the incidence rates and length of funding gaps at the principal investigator level, and to examine whether these metrics are associated with previous funding success.
Article
Management
Kaihua Chen, Chao Zhang, Ze Feng, Yi Zhang, Lutao Ning
Summary: In this paper, the technology transfer systems and modes of Chinese national research institutes are explored based on a case study of the Chinese Academy of Sciences. It is found that effective collaboration within or across the three levels of the technology transfer system can enhance integration management, resource allocation, and research and development functions. Three technology transfer modes are identified, showing an evolutionary sequence following the reform of the Chinese science and technology system and the repositioning of the Academy's mission.
Article
Cardiac & Cardiovascular Systems
David C. Goff, Denis B. Buxton, Gail D. Pearson, Gina S. Wei, Teri E. Gosselin, Ebyan A. Addou, Catherine M. Stoney, Patrice Desvigne-Nickens, Pothur R. Srinivas, Zorina S. Galis, Charlotte Pratt, Brian K. Kit, Christine Maric-Bilkan, Holly L. Nicastro, Renee P. Wong, Vandana Sachdev, Jue Chen, Lawrence Fine, Ebyan Addou, Bishow Adhikari, Sean Altekruse, Sonia Arteaga, Larissa Aviles Santa, Tim Baldwin, Ravi Balijepalli, Rebecca Beer, Carol Blaisdell, Josephine Boyington, Catherine Burke, Kristin Burns, Rebecca Campo, Drew Carlson, Marc Charette, Jue Chen, Shu Hui Chen, Sean Coady, Lawton Cooper, Narasimhan Danthi, Patrice Desvigne-Nickens, Gaya Dowling, Ray Ebert, Paula Einhorn, Lawrence Fine, Jerry Fleg, Zorina Galis, Yunling Gao, Nancy Geller, Matthew Gillam, Kathy Green, Maya Harris, Ahmed Hasan, Lucy Hsu, Alice Hurtado de Mendoza, Pamela James, Erin Iturriaga, Cashell Jaquish, Shari Ludlam, Katherine Kavounis, Fassil Ketema, Jonathan Kaltman, Dong-Yun Kim, Andrei Kindzelski, Ruth Kirby, Brian Kit, John Kunz, Eric Leifer, Huiqing Li, Lijuan Liu, Martha Lundberg, James Luo, Christine Maric-Bilkan, Marissa Miller, Cheryl Nelson, Holly Nicastro, Margaret Ochocinska, Michelle Olive, Jean Olson, Anne O'Malley, Stavroula Osganian, Young Oh, Melissa Green Parker, Charlotte Pratt, Mona Puggal, Kevin Purkiser, Nicole Redmond, Diane Reid, Jared Reis, Yves Rosenberg, Vandana Sachdev, Charlene Schramm, Lisa Schwartz-Longacre, Jane Scott, Scarlet Shi, Phyliss Sholinsky, Lorraine Silsbee, Joni Snyder, George Sopko, Pothur Srinivas, Dennis Stanley, Catherine Stoney, Wendy Taddei-Peters, Perdita Taylor-Zapata, Emily Tinsley, Olga Tjurmina, Eser Tolunay, Michael Twery, Myron Waclawiw, Jenelle Walker, Barbara Wells, Michael Wolz, Renee Wong, Jacqueline Wright, Colin Wu, Ye Yan, Song Yang
CIRCULATION RESEARCH
(2019)
Article
Public, Environmental & Occupational Health
George A. Mensah, Catherine M. Stoney, Michelle M. Freemer, Sharon Smith, Michael M. Engelgau, W. Keith Hoots, James P. Kiley, David C. Goff
ETHNICITY & DISEASE
(2019)
Review
Health Care Sciences & Services
Kenneth E. Freedland, Abby C. King, Walter T. Ambrosius, Evan Mayo-Wilson, David C. Mohr, Susan M. Czajkowski, Lehana Thabane, M. Collins, George W. Rebok, Shaun P. Treweek, Thomas D. Cook, Jack D. Edinger, Catherine M. Stoney, Rebecca A. Campo, Deborah Young-Hyman, William T. Riley
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2019)
Article
Medicine, Research & Experimental
Paula Darby Lipman, Leanora Dluzak, Catherine M. Stoney
Article
Rehabilitation
Sean D. Rundell, Linda Resnik, Patrick J. Heagerty, Amit Kumar, Jeffrey G. Jarvik
Article
Rehabilitation
Jacob Kneeman, Samuel L. Battalio, Anna Korpak, Daniel C. Cherkin, Gang Luo, Sean D. Rundell, Pradeep Suri
Summary: STarT Back tool shows good discrimination (AUC = 0.79) for future persistent disabling LBP, but calibration was poor, underestimating the risk of persistent disabling LBP. Further updating of the tool may be needed for use in VA primary care.
Article
Oncology
Lisa Gallicchio, Emily Tonorezos, Janet S. de Moor, Joanne Elena, Margaret Farrell, Paige Green, Sandra A. Mitchell, Michelle A. Mollica, Frank Perna, Nicole Gottlieb Saiontz, Li Zhu, Julia Rowland, Deborah K. Mayer
Summary: There are currently over 16.9 million cancer survivors in the United States, and this number is projected to reach 22.2 million by 2030. Despite progress in describing cancer survivors' needs and improving survivorship care, there are still evidence gaps and research priorities that need to be identified. Designing studies to address these gaps will expand our understanding of cancer survivors' diverse needs.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Orthopedics
Sean D. Rundell, Ayumi Saito, Eric N. Meier, Stephanie T. Danyluk, Jeffrey G. Jarvik, Kelley Seebeck, Janna L. Friedly, Patrick J. Heagerty, Sandra K. Johnston, Monica Smersh, Maggie E. Horn, Pradeep Suri, Amy M. Cizik, Adam P. Goode
Summary: This is a protocol for an inception cohort study of adults 50 years and older who are initiating non-surgical care for symptomatic LSS in a secondary care setting. The study aims to develop and evaluate a clinically useful model to predict long-term physical function of patients seeking non-surgical care for symptomatic LSS. Participants will be followed for 12 months, with data collected through telephone interviews, web-based surveys, and queries of electronic health records.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Meeting Abstract
Psychology, Multidisciplinary
Jun Ma, Lisa Goldman Rosas, Nan Lv, Kristen M. J. Azar, Catherine Stoney
ANNALS OF BEHAVIORAL MEDICINE
(2019)
Meeting Abstract
Psychology, Multidisciplinary
Matthew Burg, Kenneth E. Freedland, Elena Salmoirago-Blotcher, Catherine Stoney
ANNALS OF BEHAVIORAL MEDICINE
(2019)
Article
Psychology, Clinical
Susan M. Czajkowski, William T. Riley, Catherine M. Stoney, William M. P. Klein, Robert T. Croyle
JOURNAL OF BEHAVIORAL MEDICINE
(2019)
Review
Medicine, General & Internal
Luke Wolfenden, Sharni Goldman, Fiona G. Stacey, Alice Grady, Melanie Kingsland, Christopher M. Williams, John Wiggers, Andrew Milat, Chris Rissel, Adrian Bauman, Margaret M. Farrell, France Legare, Ali Ben Charif, Herve Tchala Vignon Zomahoun, Rebecca K. Hodder, Jannah Jones, Debbie Booth, Benjamin Parmenter, Tim Regan, Sze Lin Yoong
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2018)
Article
Psychology, Multidisciplinary
Krysten W. Bold, Suchitra Krishnan-Sarin, Catherine M. Stoney
AMERICAN PSYCHOLOGIST
(2018)
Meeting Abstract
Psychology, Multidisciplinary
William N. Elwood, Catherine Stoney, Dana L. Wolff-Hughes, Dawn A. Morales
ANNALS OF BEHAVIORAL MEDICINE
(2018)
Article
Psychology, Clinical
Joshua M. Smyth, Martin J. Sliwinski, Matthew J. Zawadzki, Stacey B. Scott, David E. Conroy, Stephanie T. Lanza, David Marcusson-Clavertz, Jinhyuk Kim, Robert S. Stawski, Catherine M. Stoney, Orfeu M. Buxton, Christopher N. Sciamanna, Paige M. Green, David M. Almeida
BEHAVIOUR RESEARCH AND THERAPY
(2018)