In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant

Published 2016 View Full Article

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Title
In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant
Authors
Keywords
pharmacokinetics, target binding kinetics, kinetic selectivity, in vivo, association rate constant, target-mediated drug disposition
Journal
TRENDS IN PHARMACOLOGICAL SCIENCES
Volume 37, Issue 10, Pages 831-842
Publisher
Elsevier BV
Online
2016-07-07
DOI
10.1016/j.tips.2016.06.008

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