Production of heterozygous alpha 1,3-galactosyltransferase (GGTA1) knock-out transgenic miniature pigs expressing human CD39

Production of α1,3-galactosyltransferase targeted pigs using transcription activator-like effector nuclease-mediated genome editing technology

(2016) Jung-Taek Kang et al.   Journal of Veterinary Science

The production of multi-transgenic pigs: update and perspectives for xenotransplantation

(2016) Heiner Niemann et al.   TRANSGENIC RESEARCH

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

(2016) Muhammad M. Mohiuddin et al.   Nature Communications

Pig-to-Monkey Islet Xenotransplantation Using Multi-Transgenic Pigs

(2014) R. Bottino et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Efficient generation of genetically distinct pigs in a single pregnancy using multiplexed single-guide RNA and carbohydrate selection

(2014) Ping Li et al.   XENOTRANSPLANTATION

Early Islet Damage after Direct Exposure of Pig Islets to Blood: Has Humoral Immunity Been Underestimated?

(2012) Dirk J. Van Der Windt et al.   CELL TRANSPLANTATION

Genetically modified pigs for biomedical research

(2012) Yonglun Luo et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Transgenic swine: Expression of human CD39 protects against myocardial injury

(2012) Debra G. Wheeler et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases

(2012) Ping Li et al.   JOURNAL OF SURGICAL RESEARCH

Efficient TALEN-mediated gene knockout in livestock

(2012) D. F. Carlson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting DNA With Fingers and TALENs

(2012) Daniel F Carlson et al.   Molecular Therapy-Nucleic Acids

Relative efficiency of porcine and human cytotoxic T-lymphocyte antigen 4 immunoglobulin in inhibiting human CD4+ T-cell responses co-stimulated by porcine and human B7 molecules

(2011) Tadatsura Koshika et al.   IMMUNOLOGY

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

(2011) J. Hauschild et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transgenic pigs for xenotransplantation: selection of promoter sequences for reliable transgene expression

(2010) Bernhard Aigner et al.   Current Opinion in Organ Transplantation

Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by anti-nonGal IgG binding to porcine aortic endothelial cells

(2010) C. C. LIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The coagulation barrier in xenotransplantation: incompatibilities and strategies to overcome them

(2009) Peter J Cowan et al.   Current Opinion in Organ Transplantation

Thrombotic Microangiopathy Associated with Humoral Rejection of Cardiac Xenografts from α1,3-Galactosyltransferase Gene-Knockout Pigs in Baboons

(2008) Akira Shimizu et al.   AMERICAN JOURNAL OF PATHOLOGY

Xenotransplantation: Where are we in 2008?

(2008) B. Sprangers et al.   KIDNEY INTERNATIONAL

Coagulation dysregulation as a barrier to xenotransplantation in the primate

(2008) Chih Che Lin et al.   TRANSPLANT IMMUNOLOGY

Platelet aggregation and thrombosis in xenotransplantation between pigs and humans

(2007) Baojun Zhang et al.   THROMBOSIS RESEARCH