Article
Infectious Diseases
Jun-Hee Han, Supatsak Subharat, Masako Wada, Daan Vink, Bernard J. Phiri, Ashish Sutar, Ronello Abila, Syseng Khounsy, Cord Heuer
Summary: The foot and mouth disease (FMD) vaccination program in three provinces of Lao PDR from 2016 to 2020 had varying success in reducing the prevalence of FMD virus exposure and clinical incidence. The overall impact was marginal, with factors such as operational constraints of public veterinary services, lack of farmers' compliance, and unsustainable funding contributing to the limitations of the risk-based vaccination strategy. Consistent resource availability and higher vaccination coverage are needed to effectively control FMD in Lao PDR.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Infectious Diseases
Socheat Sieng, Ian Walter Patrick, Peter Andrew Windsor, Stephen William Walkden-Brown, Chetra Sar, Robert Geoffrey Beaumount Smith, Reatrey Kong
Summary: The survey in Cambodia revealed inadequate knowledge and low vaccination coverage of FMD among farmers, leading to regular outbreaks. Farmers tended to focus on treatment rather than isolating the first infected cattle, and preferred to report outbreaks to village animal health workers, friends, neighbors, and relatives rather than government officials.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Infectious Diseases
S. Sieng, I. W. Patrick, S. W. Walkden-Brown, C. Sar
Summary: The Cambodian government is working to mobilize funding from various sectors for a coordinated FMD vaccination program. The study found that farmers would benefit from participating in the program if there are average annual outbreaks or at least two major outbreaks in the next 5 years. Factors such as vaccination success, treatment success, and coverage levels influence the overall benefits of the program.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Veterinary Sciences
Mesfin Shurbe, Bekahegn Simeon, Wasihun Seyoum, Ayelech Muluneh, Ephrem Tora, Edget Abayneh
Summary: This study revealed a high seroprevalence of foot and mouth disease (FMD) in the study area and a lack of knowledge among farmers regarding disease transmission and vaccine availability. It highlights the need for FMD vaccination campaigns and educational efforts to raise awareness among smallholder farmers about the disease transmission, FMD vaccine schedule, and vaccination importance.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Virology
Anna B. Ludi, Alison Morris, Simon Gubbins, Amin Asfor, Madeeha Afzal, Clare F. Browning, Santina Grazioli, Efrem Alessandro Foglia, Ginette Wilsden, Alison Burman, Emiliana Brocchi, David J. Paton, Donald P. King
Summary: This study quantified the cross-reactivity of foot-and-mouth disease virus (FMDV) capsid antibodies between different serotypes. The results showed that a majority of samples had positive reactions to at least one heterologous serotype. Comparative analysis of serotypes improved the accuracy of serotyping, but this method may be undermined when animals have been infected and/or vaccinated with multiple FMDV serotypes. Additionally, the study found that the integrity of the capsid may affect the specificity of SP-ELISAs.
Article
Veterinary Sciences
Tatiana Marschik, Ian Kopacka, Simon Stockreiter, Friedrich Schmoll, Joerg Hiesel, Andrea Hoeflechner-Poeltl, Annemarie Kaesbohrer, Beate Pinior
Summary: The study analyzed the economic and epidemiological impact of an FMD outbreak in Austria, finding that the success of control strategies depends on factors such as measures, geographical location, and resources. It recommended implementing an emergency strategy tailored to the affected region, with a focus on rapid detection and optimal resource allocation.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Veterinary Sciences
Svetlana Bayantassova, Kaissar Kushaliyev, Izimgali Zhubantayev, Assylbek Zhanabayev, Zhauynbay Kenzhegaliyev, Altay Ussenbayev, Assel Paritova, Gulnara Baikadamova, Temirlan Bakishev, Aitpayeva Zukhra, Askar Terlikbayev, Nurbolat Akhmetbekov, Mereke Tokayeva, Nadezhda Burambayeva, Lyailya Bauzhanova, Alma Temirzhanova, Abeldinov Rustem, Marat Aisin, Spandiyar Tursunkulov, Nurkuisa Rametov, Arman Issimov
Summary: This study assessed the KAPs of farmers and veterinary professionals towards foot-and-mouth disease (FMD) through face-to-face interviews. Results showed that a large proportion of herd owners were aware of the disease, and many had heard of FMD cases in the neighborhood. The most common clinical signs associated with FMD were oral mucosa lesions, hoof blisters, and excessive salivation. The study suggests the need for immediate actions to prevent further FMD occurrences by giving the region a status of an FMD-free zone with vaccination.
VETERINARY MEDICINE AND SCIENCE
(2023)
Article
Gastroenterology & Hepatology
Linjie Hu, Hairenguli Maimaiti, Lu Zhou, Jie Gao, Yihan Lu
Summary: This study investigated the epidemiological characteristics of Hand, foot, and mouth disease (HFMD) and the serotypes of enterovirus (EV) in Shanghai, China, after the introduction of EV-A71 vaccines. The results showed that CV-A6 was the predominant EV serotype in the HFMD epidemic, followed by CV-A16 and EV-A71. The changing trends in EV serotypes influenced the periodicity of the HFMD epidemic. A minority of HFMD cases had comorbidities, but they were not correlated with EV serotypes. The use of EV-A71 vaccine had an impact on the HFMD epidemic, and it may promote vaccination in children infected with EV-A71.
Article
Veterinary Sciences
Simon Gubbins, David J. Paton, Aldo Dekker, Anna B. Ludi, Ginette Wilsden, Clare F. J. Browning, Michael Eschbaumer, Jamie Barnabei, Hernando Duque, Lisa L. Pauszek, Donald P. King
Summary: Serology plays an important role in predicting the immune protection of vaccinated individuals and populations against infectious diseases. Studies on foot-and-mouth disease show that neutralising antibody titres correlate with protection, but there is significant variability in cross-strain protection. Further research is needed to understand the factors contributing to this variability and establish more reliable antibody thresholds.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Infectious Diseases
Polly Compston, Georgina Limon, Barbara Hasler
Summary: This study described and assessed the methods used in economic analyses of foot-and-mouth disease (FMD) and its control in endemic contexts. A systematic literature search identified 64 articles from 26 countries, which revealed that the methods used in these analyses were poorly reported. Additionally, the studies often failed to differentiate between public and private costs of FMD control or consider the economic or social influences of vaccination program scale.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Veterinary Sciences
Arash Osmani, Ian Duncan Robertson, Ihab Habib
Summary: A serological study and survey of farmers in 53 villages in Khinjan, Doshi, and Puli Khumri districts of Baghlan province, Afghanistan were conducted to determine the seroprevalence of Foot and Mouth Disease (FMD). The study found a seroprevalence of 42.0% for FMD in cattle, with factors such as age, cattle purchase behavior, milk selling behavior, and vaccination status influencing the likelihood of a herd being seropositive. This study provides valuable insights for disease control efforts against FMD in Baghlan province and other provinces in Afghanistan.
VETERINARY MEDICINE AND SCIENCE
(2021)
Article
Microbiology
Zhidong Zhang, Ryan Waters, Yanmin Li
Summary: Foot-and-mouth disease virus (FMDV) infection causes epithelial cell lesions and muscle-associated lesions in cloven-hoofed animals, leading to high mortality. Current knowledge about the non-epithelial tropism of FMDV remains limited.
VETERINARY MICROBIOLOGY
(2021)
Article
Virology
Andrea Isabel Estevez Garcia, David J. Lefebvre, Lionel Nyabongo, Andy Haegeman, Canesius Nkundwanayo, Annebel De Vleeschauwer, Desire Ntakirutimana, Ilse De Leeuw, Deogratias Nsanganiyumwami, Pascal Niyokwizera, Thierry van den Berg, Alfred Niyokwishimira, Kris De Clercq
Summary: This study reports the occurrence of foot-and-mouth disease in Burundi and investigates the affected cattle herds. The study finds that the foot-and-mouth virus is widely spread in the affected regions, with different serotypes. Additionally, the isolated virus strains have similarities with strains from other countries in the region, suggesting possible transboundary transmission.
Article
Veterinary Sciences
Mattia Begovoeva, David O. Ehizibolo, Adeyinka J. Adedeji, Moses O. Oguche, Olumuyiwa Oyekan, Sandra I. Ijoma, Rebecca B. Atai, Yiltawe Wungak, Banenat B. Dogonyaro, David D. Lazarus, Mark Samson, Hussaini Ularamu, Maryam Muhammad, Fabrizio Rosso, Keith J. Sumption, Philippa M. Beard, Anna B. Ludi, Kim B. Stevens, Georgina Limon
Summary: A cross-sectional study was conducted in northern Nigeria to examine the role of small ruminants in the epidemiology of foot-and-mouth disease (FMD). The study found that small ruminants infected with FMD can spread the virus silently within domestic and wildlife species. The true seroprevalence of FMD in backyard small ruminants was estimated to be 10.2%, with spatial heterogeneity observed across the study area. Risk factors for FMD seropositivity were identified at animal and household levels, with state and species being the main factors. Overall, this study provides important insights into the epidemiology of FMD in small ruminants.
PREVENTIVE VETERINARY MEDICINE
(2023)
Article
Agriculture, Dairy & Animal Science
Hend M. El Damaty, Elshaima M. Fawzi, Ahmed N. F. Neamat-Allah, Ibrahim Elsohaby, Abdelmonem Abdallah, Gamelat K. Farag, Yousry A. El-Shazly, Yasser S. Mahmmod
Summary: Continuous mutations of the foot and mouth disease virus lead to the emergence of new topotypes and lineages, contributing to occasional vaccination failures. The circulating SAT-2 serotype of FMDV in water buffaloes in Egypt, closely related to the lib12 lineage, topotype VII, played a significant role in the high morbidity rate of the FMD outbreak in early 2019.
Article
Materials Science, Biomaterials
Kamlesh V. Chandekar, Mohd. Shkir, Thamraa Alshahrani, Essam H. Ibrahim, Mona Kilany, Zubair Ahmad, M. Aslam Manthrammel, S. AlFaify, Babak Kateb, Ajeet Kaushik
Summary: This research presents the synthesis of PAA-coated CF core-shell magnetic nanoparticles for biomedical applications. The NPs demonstrated good antimicrobial performance and biocompatibility with normal splenic cells. In vivo studies are needed to further explore biodistribution and chronic toxicity.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Biology
Enas A. A. Alabdali, Hamed A. Ghramh, Essam H. Ibrahim, Zubair Ahmad, Asma N. Asiri
Summary: The study found a new hybrid or subspecies of bees collected in the southwestern region of Saudi Arabia through morphological and molecular analyses. Different from previous studies, the presence of a new hybrid species indicates the emergence of novel hybridization in the region.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Essam H. Ibrahim, Hamed A. Ghramh, Mona Kilany
Summary: After the outbreak of the COVID-19 pandemic, the development of specific and sensitive enzyme immunoassay (EIA) has shown high specificity and sensitivity for detecting SARS-CoV-2, serving as a valuable tool for diagnostics.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2021)
Article
Biology
Mohammad Y. Alshahrani, Essam H. Ibrahim, Mohammed Asiri, Mona Kilany, Ahmad Alshehri, Ali G. Alkhathami, Kareem Morsy, Harish C. Chandramoorthy
Summary: The study found that the ethanolic extract of Coccinia indica exhibited inhibitory effects on MRSA, Candida auris, and Streptococcus pyogenes, while showing weaker effects on E. coli and Trichophyton rubrum. The aqueous extract did not show any inhibitory effects. The results demonstrate concentration-dependent antibacterial and antifungal activities of the plant extract, suggesting its potential in combating multidrug resistance.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Environmental Sciences
Ali S. Alshehri, Attalla F. El-Kott, Ayman E. El-Kenawy, Mohamed Samir A. Zaki, Kareem Morsy, Reham A. Ghanem, Eman T. Salem, Eman R. Ebealy, Heba S. Khalifa, Ahmed E. Altyar, Hussah I. M. AlGwaiz, Essam H. Ibrahim, Mohammed S. Mahmoud, Mohammad A. Dallak, Eman M. Abd-Ella
Summary: This study demonstrates that kaempferol has a nephroprotective effect against cadmium-induced nephropathy by reducing kidney damage, improving kidney function, and attenuating oxidative stress and inflammation. It achieves these effects by suppressing NF-kappa B p65 and activating Nrf2.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Multidisciplinary Sciences
Essam H. Ibrahim, Mohammad Y. Alshahrani, Hamed A. Ghramh, Hani Alothaid, Mona Kilany, Kareem Morsy, Attalla F. El-kott, Ramadan Taha, Haitham El-Mekkawy, Gamal A. EL-Shaboury, Ahmed A. El-Mansi, Mohammed E. A. Mohammed, Mahmoud A. Sayed, Ibrahim S. Yahia
Summary: The study demonstrates that Origanum majorana leaf acetone extract has anti-colorectal cancer effects by inducing cell division arrest and apoptosis in HT-29 human colon cancer cells.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Multidisciplinary Sciences
Badria M. AL-Shehri, Reham M. Mashat, Rahaf M. H. Alshareef, Wed Mohammed Ali Alaerjani, Khalid Ali Khan, Hamed A. Ghramh, Essam H. Ibrahim, Majed A. Bajaber, Abdulaziz A. Zarbah, Mohammed Elimam Ahamed Mohammed
Summary: This study investigated the presence of artificial sweeteners in honey samples from Asir region-Saudi Arabia and measured their concentration along with glucose oxidase (GOX) activity and other quality parameters. The results showed that Acacia and Zizphus honey samples contained high amounts of sorbitol and trace levels of xylitol. The floral origin and year of harvest significantly influenced the pH, electric conductivity, and acidity of the honey samples.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
F. El-Sayed, Mai S. A. Hussien, T. H. AlAbdulaal, Abdel-Haleem Abdel-Aty, H. Y. Zahran, I. S. Yahia, Mohamed Sh. Abdel-wahab, Essam H. Ibrahim, Medhat A. Ibrahim, Hanan Elhaes
Summary: Cationic dye (methylene blue) and anionic dye (carmine) degradation were demonstrated using SrO and G-SrO NPs. The efficacy of photocatalysis and electro & photo-electrocatalytic oxidation in degrading carmine dye was compared. The study found that graphene-modified SrO nanoparticles showed improved photocatalytic activity and the 0.25G-SrO catalyst achieved high degradation efficiency for methylene blue dye under UV light.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Multidisciplinary Sciences
Mohammad Y. Alshahrani, Essam H. Ibrahim, Mohammed Asiri, Mona Kilany, Ali G. Alkhathami, Mohammed N. Alshahrani, Harish C. Chandramoorthy
Summary: The addition of lycopene to the extract enhances the antioxidant and antibacterial activities, showing potential inhibition against multidrug-resistant bacteria.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Veterinary Sciences
K. Morsy, S. B. Dajem, A. Alghamdi, A. El-kott, E. Ibrahim, K. Attia, A. Al-Doaiss, H. El-Mekkawy, N. Sheraba, A. Baiomy, M. Fahmy, F. Shalaby
Summary: In 2020, 52 marine fish specimens were caught from boat landing sites along the Alexandria coast in Egypt. Among them, 30 fish were found to be infected with three different parasitic species, which can negatively impact fish health and lead to consumers rejecting the fish.
ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA
(2023)
Article
Parasitology
Kareem Morsy, Saad Bin Dajem, Mohammed Al-Kahtani, Attalla El-Kott, Essam Ibrahim, Hamida Hamdi, Amin Al-Doaiss, Mohamed Abumandour, Haitham El-Mekkawy, Diaa Massoud, Asmaa Adel, Shams Abd El-Kareem
Summary: Members of the order Trypanorhyncha are cestode parasites that infect the muscles of marine fish, affecting fish health and consumer behavior. This study identified four different species of parasites and confirmed their taxonomic position through molecular analysis. The results emphasize the importance of removing parasites during the commercialization of fish.
REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA
(2022)
Article
Pharmacology & Pharmacy
Essam Hassan Ibrahim, Mohammad Yahya Alshahrani, Hamed Ali Ghramh, Hani Alothaid, Mona Kilany, Kareem Morsy, Ramadan Taha, Khalid Mushabab Al Syaad, Haitham Ibrahim El-Mekkawy, Gamal Awad EL-Shaboury, Ahmed Abdel Aziz El-Mansi, Ahmad Alamri, Mahmoud Ahmed Sayed, Ibrahim Sayed Yahia, Rahaf Mohammed Hussein Alshareef, Badria Mohammed Al-Shehri, Mohammed Elimam Ahamed Mohammed
Summary: This study investigated the biological effects of Moringa oleifera leaf extract (MOE) alone or in combination with silver nanoparticles (AgNPs) on colon cancer and microbial cell growth. The results showed that MOE had mild antibacterial effects and increased apoptosis and p53 protein expression in colon cancer cells. MOE also arrested cell cycle at G2/M phase and stimulated splenic cell growth. Both extract preparations exhibited antioxidant activities. Thus, MOE can be utilized as an anticancer agent.
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Environmental Sciences
Hamed A. Ghramh, Rahmah N. Al-Qthanin, Zubair Ahmad, Khalid Ali Khan, Essam H. Ibrahim, Habeeb Mansour A. Al-Solami, Ahlam Khalofah, Abeer Alahmari, Farhat S. Khan, Asma N. Asiri, Sally Negm, Mogbel Ahmed Abdalla El-Niweri, Fawziah M. Asiri
Summary: This study investigated the larvicidal toxicity of silver nanoparticles synthesized from the ethanol extract of S. palmeri against 4th instar larvae of Ae aegypti. The results showed that the silver nanoparticles were more effective in killing mosquitoes compared to the original extract.
FRESENIUS ENVIRONMENTAL BULLETIN
(2022)
Article
Zoology
Essam H. Ibrahim, Attalla F. El-kott, Ali Alshehri, Mona Kilany, Reza Yavari, Salahud Din, Diaa Massoud
Summary: The morphology and histology of the tongue in two adult Asian bears were examined using light and scanning electron microscopy, revealing four types of papillae. The tongue was covered by a keratinized stratified squamous epithelium, with a dense connective tissue making up the lamina propria and thick masses of striated muscles forming the bulk of the tongue. Lingual salivary glands with seromucous secretions were also present in the lingual root.
PAKISTAN JOURNAL OF ZOOLOGY
(2022)
Article
Biology
Attalla El-Kott, Eman Elbealy, Fahmy Elsaid, Haitham El-Mekkawy, Abd-El-Karim Abd-Lateif, Abdulali Taweel, Heba Khalifa, Ahmad Kandeel, Kareem Morsy, Essam Ibrahim, Mashael Mohammed Bin-Meferij
Summary: The study found that Pterostilbene inhibited the survival of SKOV3 ovarian cancer cells, increased levels of cellular lysate products, and induced apoptosis in the cells. This anti-tumor effect is mainly achieved by inhibiting cell metabolism and regulating mTOR through AMPK and Akt pathways.