Multiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARP

Retromer and sorting nexins in endosomal sorting

(2015) Matthew Gallon et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes

(2015) Soujiro Marubashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STX13 regulates cargo delivery from recycling endosomes during melanosome biogenesis

(2015) R. A. Jani et al.   JOURNAL OF CELL SCIENCE

Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes

(2015) Bjorn D. M. Bean et al.   MOLECULAR BIOLOGY OF THE CELL

Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes

(2015) A. Yatsu et al.   Biology Open

VARP Is Recruited on to Endosomes by Direct Interaction with Retromer, Where Together They Function in Export to the Cell Surface

(2014) Geoffrey G. Hesketh et al.   DEVELOPMENTAL CELL

Identification of molecular heterogeneity in SNX27-retromer-mediated endosome-to-plasma-membrane recycling

(2014) I. J. McGough et al.   JOURNAL OF CELL SCIENCE

GWAS identifies four novel eosinophilic esophagitis loci

(2014) Patrick M. A. Sleiman et al.   Nature Communications

Lysosome-related organelles: unusual compartments become mainstream

(2013) Michael S Marks et al.   CURRENT OPINION IN CELL BIOLOGY

Rabex-5 Protein Regulates Dendritic Localization of Small GTPase Rab17 and Neurite Morphogenesis in Hippocampal Neurons

(2013) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Syntaxin-3 Is Required for Melanosomal Localization of Tyrp1 in Melanocytes

(2013) Ayaka Yatsu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

BLOC-3 Mutated in Hermansky-Pudlak Syndrome Is a Rab32/38 Guanine Nucleotide Exchange Factor

(2012) Andreas Gerondopoulos et al.   CURRENT BIOLOGY

A Molecular Network for the Transport of the TI-VAMP/VAMP7 Vesicles from Cell Center to Periphery

(2012) Andrea Burgo et al.   DEVELOPMENTAL CELL

Role of Rab family GTPases and their effectors in melanosomal logistics

(2012) N. Ohbayashi et al.   JOURNAL OF BIOCHEMISTRY

Small GTPase Rab17 Regulates Dendritic Morphogenesis and Postsynaptic Development of Hippocampal Neurons

(2012) Yasunori Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BLOC-2, AP-3, and AP-1 Proteins Function in Concert with Rab38 and Rab32 Proteins to Mediate Protein Trafficking to Lysosome-related Organelles

(2012) Jarred J. Bultema et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation

(2012) Ingmar B Schäfer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hermansky-Pudlak syndrome: pigmentary and non-pigmentary defects and their pathogenesis

(2012) Ai-Hua Wei et al.   Pigment Cell & Melanoma Research

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

(2011) Alexander Zimprich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

VPS35 Mutations in Parkinson Disease

(2011) Carles Vilariño-Güell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Characterization of RIN3 as a Guanine Nucleotide Exchange Factor for the Rab5 Subfamily GTPase Rab31

(2011) Hiroaki Kajiho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology

(2011) Lei Wen et al.   JOURNAL OF CELL BIOLOGY

The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes

(2011) Norihiko Ohbayashi et al.   MOLECULAR BIOLOGY OF THE CELL

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Thousands of Rab GTPases for the Cell Biologist

(2011) Yoan Diekmann et al.   PLoS Computational Biology

Structure-Function Analysis of VPS9-Ankyrin-repeat Protein (Varp) in the Trafficking of Tyrosinase-related Protein 1 in Melanocytes

(2010) Kanako Tamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

(2010) Shin-ichiro Yoshimura et al.   JOURNAL OF CELL BIOLOGY

Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth

(2009) Andrea Burgo et al.   EMBO REPORTS

A 25bp-long insertional mutation in the BmVarp gene causes the waxy translucent skin of the silkworm, Bombyx mori

(2009) Katsuhiko Ito et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Varp Is a Novel Rab32/38-binding Protein That Regulates Tyrp1 Trafficking in Melanocytes

(2009) Kanako Tamura et al.   MOLECULAR BIOLOGY OF THE CELL

ESCRT-I Function is Required for Tyrp1 Transport from Early Endosomes to the Melanosome Limiting Membrane

(2009) Steven T. Truschel et al.   TRAFFIC

Roles of endosomal trafficking in neurite outgrowth and guidance

(2009) Sharon Sann et al.   TRENDS IN CELL BIOLOGY

Varp interacts with Rab38 and functions as its potential effector

(2008) Fang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Membrane traffic in the secretory pathway

(2008) M. Fukuda   CELLULAR AND MOLECULAR LIFE SCIENCES

Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity

(2008) Mitsunori Fukuda et al.   MOLECULAR & CELLULAR PROTEOMICS