Article
Chemistry, Analytical
Zi-Tao Zhong, Ghazala Ashraf, Wei Chen, Lai-Bo Song, Shu-Jie Zhang, Bo Liu, Yuan-Di Zhao
Summary: Duplex-specific nuclease (DSN) is a promising tool for bioanalysis due to its unique capability to cleave DNA within duplexes. This study proposes a new sensing strategy by coupling DSN with DNA aptamer sequence for diverse analytes detection with signal amplification and cycling. The method shows satisfactory performance in detecting adenosine triphosphate, thrombin, and alpha-fetoprotein.
MICROCHEMICAL JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Li Li, Zhengbo Chen
Summary: In this study, a high specificity, flexibility, and simplicity aptasensor strategy was designed using a triblock DNA probe. It was found that the polyA fragment could assemble on the gold electrode surface via polyA instead of traditional Au-S bonds, leading to improved hybridization stability. The electrochemical aptasensor showed good repeatability, stability, and specificity.
BIOELECTROCHEMISTRY
(2023)
Review
Chemistry, Analytical
Ranran Xu, Yongqiang Cheng, Xiaotong Li, Ziwei Zhang, Meijia Zhu, Xiaoxiao Qi, Longyu Chen, Lin Han
Summary: This review highlights the recent progress in high-sensitivity bioanalytical applications based on aptamer signal amplification strategies on microchips. The challenges in practical application are discussed, and the future development is prospected.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Ruoyu Wu, Jiaping Guo, Minkai Wang, Huimin Liu, Lihua Ding, Ruiying Yang, Li-e Liu, Zhiyong Liu
Summary: In this study, a sensitive and specific fluorescent sensor based on magnetic separation technology combined with chain displacement amplification was developed for fast and easy detection of Ochratoxin A (OTA) in food. The method showed excellent performance with a linear range of 0.5-128.0 ng/mL, a detection limit of 0.125 ng/mL, and relative standard deviations of 3.92-7.71%. Furthermore, the method was successfully applied to determine OTA in wheat, corn, and red wine samples.
Article
Chemistry, Analytical
Yong-Qiang He, Ying Chen, Xian-Zhu Meng, Hong -Chao Yi, Hui-Wen Gu, Xiao-Li Yin
Summary: A visual and smartphone-integrated aptasensor for rapid Staphylococcus aureus determination was developed using Exo III-assisted recycling and hemin/G-quadruplex DNAzymes for signal amplification. The assay quantified the released DNAzymes via Exo III-assisted recycling reaction and analyzed them with a smartphone and UV-Vis spectrophotometer. This method exhibited good analytical performance, low cost, and portability, making it a rapid point-of-care test method with great potential in food safety control.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Juyoung Kang, Hyungjun Jang, Gyuho Yeom, Min-Gon Kim
Summary: The study developed a protein detection method based on a heterogeneous sandwich-type sensing platform, which can achieve high specificity and sensitivity. This method can detect biomarkers in various infectious diseases, including SARS-CoV-2, with low cross-reactivity. Clinical sample testing confirmed the effectiveness of the proposed method.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Feng Qiu, Xiaoyan Gan, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: This study presents a novel method for sensitive detection of thrombin in human serums. By utilizing target-promoted magnetic nanoparticle-decorated DNA polymers for proximity binding hybridization chain reaction, the detection of thrombin is significantly enhanced.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Review
Chemistry, Analytical
Yulin Deng, Hao Jiang, Xiaoqiong Li, Xuefei Lv
Summary: The review summarizes methods for improving the sensitivity of lateral flow assay (LFA), such as sample pretreatment, flow rate changes, and label evolution, and discusses the future development direction and challenges of LFAs.
Review
Biochemistry & Molecular Biology
Minhyuk Lee, Seonhye Shin, Sungjee Kim, Nokyoung Park
Summary: Aptamers, as promising bio-recognition elements, have advantages such as specificity, high affinity, and easy synthesis. Fluorescent aptasensors are widely used in biological applications due to their high sensitivity, simple detection process, and low cost.
Article
Chemistry, Analytical
Limin Yang, Heng Guo, Qian Gao, Ting Hou, Jingang Zhang, Xiaojuan Liu, Feng Li
Summary: The researchers successfully achieved highly sensitive detection of exosomal miRNA by integrating three-dimensional DNA nanomachines and magnetic separation into a homogeneous electrochemical strategy. The method has low background, multiple signal amplification, and good anti-interference ability, making it suitable for noninvasive early disease diagnosis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Khalil Abnous, Ali khakshour Abdolabadi, Mohammad Ramezani, Mona Alibolandi, Morteza Alinezhad Nameghi, TaranehSadat Zavvar, Zahra Khoshbin, Parirokh Lavaee, Seyed Mohammad Taghdisi, Noor Mohammad Danesh
Summary: By utilizing signal amplification elements of TdT and CRISPR-Cas12a, a highly sensitive and simple electrochemical aptasensor was developed for cocaine quantification, demonstrating excellent selectivity and potential for diverse applications in analyte determination.
Article
Chemistry, Analytical
Ghasem Anbiaee, Zahra Khoshbin, Hamed Zahraee, Mohammad Ramezani, Mona Alibolandi, Khalil Abnous, Seyed Mohammad Taghdisi
Summary: Developing cost-effective smart sensing tools with ultrahigh sensitivity for food safety insurance is highly important. Aptamer-based biosensors powered by recycling signal amplification strategies, such as target recycling supported by enzymes, have shown great potential in achieving signal amplification. Exonucleases, as superior biocatalysts, simplify the amplification process and exhibit outstanding selectivity and sensitivity, making them promising sensing tools for label-free, ease-of-use, cost-effective, and real-time diagnosis of diverse targets. This article summarizes the achievements and perspectives in aptasensor design for qualitative monitoring of diverse targets using exonucleases for signal amplification.
Article
Chemistry, Physical
Yinzhu Lu, Bingqian Lin, Weizhi Liu, Jialu Zhang, Lin Zhu, Chaoyong Yang, Yanling Song
Summary: A modular platform is developed for sequential isolation of tumor and non-tumor extracellular vesicles (EVs) using dual-aptamer recognition and tandem microchips. This method provides new clues for assessing immune heterogeneity and can be used for EV proteome profiling.
Review
Chemistry, Multidisciplinary
Yongxi Zhao, Xiaolei Zuo, Qian Li, Feng Chen, Yan-Ru Chen, Jinqi Deng, Da Han, Changlong Hao, Fujian Huang, Yanyi Huang, Guoliang Ke, Hua Kuang, Fan Li, Jiang Li, Min Li, Na Li, Zhenyu Lin, Dingbin Liu, Juewen Liu, Libing Liu, Xiaoguo Liu, Chunhua Lu, Fang Luo, Xiuhai Mao, Jiashu Sun, Bo Tang, Fei Wang, Jianbin Wang, Lihua Wang, Shu Wang, Lingling Wu, Zai-Sheng Wu, Fan Xia, Chuanlai Xu, Yang Yang, Bi-Feng Yuan, Quan Yuan, Chao Zhang, Zhi Zhu, Chaoyong Yang, Xiao-Bing Zhang, Huanghao Yang, Weihong Tan, Chunhai Fan
Summary: Nucleic acids are natural biopolymers that play central roles in storing, encoding, transmitting and expressing genetic information. The field of nucleic acids analysis has rapidly advanced with technological breakthroughs, leading to the development of new analysis methods. However, there are also challenges and further research needed in this area.
SCIENCE CHINA-CHEMISTRY
(2021)
Article
Chemistry, Analytical
Mengni Sun, Na Ma, Hanxing Shi, Ling-Zhi Cheong, Wenge Yang, Zhaohui Qiao
Summary: A multivalent aptamer based on hybridization chain reaction (HCR) was designed as an effective signal amplifier for the sensitive detection of Salmonella. The multi-Apt exhibited a 33-fold enhancement in binding affinity and faster reaction kinetics compared to the monovalent aptamer (mono-Apt). By utilizing the HCR scaffold as a signal carrier, the proposed HCR-based multi-Apt amplifier could detect Salmonella as low as 7 cfu mL-1 with a broad detection range of 10 to 107 cfu mL-1. It also demonstrated excellent specificity against target bacteria and performed well on the detection of spiked food samples, showing great potential in practical Salmonella detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Materials Science, Multidisciplinary
Guodong Li, Liuhe Li, Mingyue Han, Sida Luo, Jie Jin, Lei Wang, Jiabin Gu, Hu Miao
Article
Chemistry, Physical
Yanan Wang, Zhaoxia Niu, Junyu Chen, Yujiang Zhai, Ye Xu, Sida Luo
Article
Multidisciplinary Sciences
Mustafa Danish, Sida Luo
SCIENTIFIC REPORTS
(2019)
Article
Multidisciplinary Sciences
Mingxuan Bai, Yujiang Zhai, Fu Liu, Yanan Wang, Sida Luo
SCIENTIFIC REPORTS
(2019)
Article
Nanoscience & Nanotechnology
Junyu Chen, Yanan Wang, Fu Liu, Sida Luo
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Chemistry, Analytical
Mustafa Danish, Sida Luo
Article
Chemistry, Multidisciplinary
Yanan Wang, Guantao Wang, Meihong He, Fu Liu, Mingguang Han, Tan Tang, Sida Luo
Summary: Functional surfaces with tunable and patternable wettability have been developed using laser-induced graphene papers, allowing for continuous tuning of wettability from superlyophilicity to superlyophobicity. The designable processes for achieving various wetting patterns have enabled multifunctional and multi-scenario applications in biomedical, environmental, and energy storage fields.
Article
Materials Science, Composites
Fu Liu, Guantao Wang, Xilun Ding, Sida Luo
Summary: Laser-induced graphene (LIG) offers advantages such as swift and simple process, tunable microstructures, and properties for multifunctional composites. A new process combining extrusion-printing and LIG was proposed, allowing for the assembly of multifunctional graphene coatings on polymeric composites. The resulting LIG integrated composites (LIGC) exhibited multiple functions, including strain-mapping, anti-icing, de-icing, and flame-retardant efficiency.
COMPOSITES COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Meihong He, Guantao Wang, Yuxiang Zhu, Yanan Wang, Fu Liu, Sida Luo
Summary: By introducing joule heating as a critical in-situ treatment, the specific surface area and pore volume of the laser-induced graphene paper can be improved for enhanced capacitive performance. Optimizing the heating temperature and time can significantly increase the specific areal capacitance of the MSCs.
Article
Chemistry, Multidisciplinary
Yan Gao, Yujiang Zhai, Guantao Wang, Fu Liu, Haibin Duan, Xilun Ding, Sida Luo
Summary: A new laser-induced graphene (LIG) protocol is developed in this study for facile stacking and shaping of 3D macrostructures. The constructed 3D LIGP composites (LIGP-C) have the advantages of large area, high thickness, and customizable flat or curved shapes, while maintaining the highest levels of mechanical and electrical properties. Additionally, the study explores the influence of critical processing parameters on the multifunctional properties of LIGP-C.
Article
Nanoscience & Nanotechnology
Dan Wang, Jiebo Li, Yanan Wang, Fu Liu, Guantao Wang, Xilun Ding, Sida Luo, Geng Chen
Summary: This study systematically investigates the antibacterial activities of laser-induced graphene and identifies the interconnected open-cell network with the highest specific surface area as the determining factor for bacteria trapping.
ACS APPLIED NANO MATERIALS
(2022)
Article
Computer Science, Information Systems
Yang YUAN, Yimin DENG, Sida LUO, Haibin DUAN
Summary: This study investigates a distributed game strategy for unmanned aerial vehicle (UAV) formations with external disturbances and obstacles. The strategy is based on a distributed model predictive control (MPC) framework and Levy flight based pigeon inspired optimization (LFPIO). The proposed strategy includes an observer for disturbance estimation, an obstacle avoidance strategy based on topology reconstruction, and a distributed MPC framework.
FRONTIERS OF INFORMATION TECHNOLOGY & ELECTRONIC ENGINEERING
(2022)
Article
Chemistry, Multidisciplinary
Fu Liu, Yan Gao, Guantao Wang, Dan Wang, Yanan Wang, Meihong He, Xilun Ding, Haibin Duan, Sida Luo
Summary: 3D printing is an important strategy for constructing graphene smart structures with arbitrary shapes and complexities. A new laser-induced graphene-based additive manufacturing (LIG-AM) protocol was developed to form bulk 3D graphene with freeform structures without using additional binders, templates, and catalysts. This method enables the assembly of various types of graphene architectures and allows for control of processing efficiency and assembling resolution. By studying the properties, a LIG-AM enabled aircraft-wing section model was printed to demonstrate its shiftable process, hybridizable structure, and multifunctional performance.
Article
Nanoscience & Nanotechnology
Mingguang Han, Xilun Ding, Haibin Duan, Sida Luo, Geng Chen
Summary: This paper proposes a new combination of humidity sensing materials for assembling thin-film based capacitive-type sensors. By using PA-doped polybenzimidazole (PA-PBI) as an electrolyte and laser-carbonized PA-PBI as a carbon electrode (PA-PBI-C), the flexible sensor achieves excellent humidity-sensing performances with high sensitivity, fast response time, and low hysteresis. The study also establishes a synergistic sensing mechanism consisting of a Water reservoir and a Bridge to support advanced health-monitoring applications.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Materials Science, Biomaterials
Tan Tang, Tujun Weng, Hongxing Jia, Sida Luo, Ye Xu, Liuhe Li, Peipei Zhang
BIOMATERIALS SCIENCE
(2019)
Review
Chemistry, Analytical
Claudia Campanale, Silvia Galafassi, Francesca Di Pippo, Iulian Pojar, Carmine Massarelli, Vito Felice Uricchio
Summary: Biodegradable plastic mulches (BDMs) have the potential to be an eco-friendly alternative to conventional plastic mulches in agriculture. However, their long-term impacts on soil ecosystems are still uncertain, and further research is needed. Incorporating BDMs into the soil may stimulate microbial activity, but there is also a risk of incomplete degradation and release of residual microplastics and additives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Yaxin Cao, Longyi Shao, Timothy P. Jones, Wenjing Deng, M. Santosh, Pengju Liu, Cheng-Xue Yang, Yaowei Li, Daizhou Zhang, Kelly Berube
Summary: The toxicity of fibrous particles in ambient air can be higher than other types of particles. Microfibers can be organic or inorganic and their presence in the atmosphere as a result of human activity raises concerns for environmental and public health. Accurate collection, identification, and understanding of the health hazards associated with these fibers are crucial for mitigation strategies and protection of public health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Chenchen Xie, Chen Meng, Huilin Liu, Baoguo Sun
Summary: The development of food hazard factor (FHF) detection has been moving towards on-site inspection and mobile law enforcement, calling for simple, fast, and affordable analysis technology to ensure food safety and quality. This review comprehensively summarizes the progress in research on smartphone-assisted MIP optosensors, focusing on the key issues of accuracy and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Guillem Peris-Pastor, Cristian Azorin, Jose Grau, Juan L. Benede, Alberto Chisvert
Summary: Green Analytical Chemistry plays an important role in every stage of method development, including sample preparation. Extraction techniques have evolved from conventional ones to a variety of miniaturized techniques in order to enhance analytical performance and ensure safety for operators and the environment. Green metric tools are used to evaluate the impact and sustainability of methods, with AGREEprep selected as the most suitable tool for evaluating published methods in various applications. The miniaturization of sample preparation strategies has led to the use of less and safer solvents, reduced waste generation and energy consumption, and improved portability and throughput.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Helena Hruskova, Roman Reminek, Frantisek Foret
Summary: This review article summarizes the progress and recent studies in offline electromigration preparative techniques between 2018 and 2023. It covers various techniques including electrophoresis, free-flow electrophoresis, isoelectric focusing, and isotachophoresis, providing theoretical aspects, trends, and solutions to existing limitations in each technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Ivneet Banga, Anirban Paul, Nathan Kodjo Mintah Churcher, Ruchita Mahesh Kumar, Sriram Muthukumar, Shalini Prasad
Summary: Breathomics is an emerging field that focuses on analyzing exhaled breath to diagnose and monitor respiratory diseases. Electrochemical sensors, with their high sensitivity, selectivity, and low cost, play a significant role in breathomics and can be integrated into portable devices for point-of-care diagnosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Fabjola Bilo, Paola Cirelli, Laura Borgese
Summary: This review explores the application of X-ray fluorescence (XRF) spectrometry for elemental analysis of particulate matter (PM) in air quality monitoring. It discusses the fundamentals of XRF, experimental configurations, PM sampling devices and substrate, sample preparation strategies, qualitative and quantitative analysis, as well as the challenges faced by XRF in becoming a reliable analytical technique for PM analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hakim Faraji
Summary: The dispersive liquid-liquid microextraction (DLLME) technique is widely popular in analytical chemistry due to its high efficiency, cost-effectiveness, and simplicity. Recent advancements have addressed the limitations of DLLME, incorporating greener solvents, innovative dispersion strategies, and simplified procedures. These changes have made DLLME a more sustainable and efficient technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli, Fotouh R. Mansour
Summary: Carbon nanomaterials (CNMs) have excellent capabilities in terms of adsorption, enhanced oxidation, and photocatalysis, attracting widespread attention in different fields. Metal-organic frameworks (MOFs) have been widely used due to their regular network structure, porous nature, and large specific surface area. However, the instability of MOFs in aqueous solutions limits their applications in chemical sensing. Recent studies have focused on increasing the stability of MOFs in water-based matrices through chemical modifications using CNMs.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Alexandra Pape, Oliver J. Schmitz
Summary: Low temperature plasmas based on dielectric barrier discharges have emerged as a recent development in ion source research. These ion sources are applicable to heat-sensitive analytes and can ionize a wide range of compounds. Despite intensive research on important parameters such as configuration, shape, size, and materials in the past two decades, the actual ionization mechanism for all plasma gases has not been fully elucidated. This review provides an overview of atmospheric pressure ion sources, with a focus on plasma and dielectric barrier discharge based ion sources, summarizing the reactions occurring in the plasma and discussing the applications developed by different research groups.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hai Xiong, Fengli Li, Linyu Zeng, Qiyu Lei
Summary: This review provides an overview of the emerging trends in the use of functional COF nanomaterials as biosensors for DNA/RNA detection. It summarizes the construction of DNA/RNA hybridized COF nanoprobes and their potential applications in bioanalyte detection, biosensing, biomarker imaging, and clinical biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Bing Yan
Summary: This article summarizes the recent progress in logic gate computing and operation based on multiple luminescence response and chemical sensing for lanthanide functionalized MOF hybrid systems. The article first describes multi-color luminescence and the subsequent multiple luminescence response. The basic concept of logic gate operation and the advantages of lanthanide-based hybrid materials are then introduced. Reports on logic gate operation using pure lanthanide MOFs are provided, followed by a detailed summary of logic gate operations using lanthanide functionalized MOF hybrid materials. Additionally, the article discusses the practical luminescent detection of analytes by correlating the luminescence responsive signals and the concentration of different analytes. Finally, the article concludes with a prospect for this topic.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Brij Mohan, Gurjaspreet Singh, Rakesh Kumar Gupta, Pawan Kumar Sharma, Alexander A. Solovev, Armando J. L. Pombeiro, Peng Ren
Summary: Porous materials, particularly hydrogen-bonded organic frameworks (HOFs), have gained significant attention due to their versatile applications and unique properties such as well-defined crystalline structure and easy regeneration processes. This article provides a comprehensive overview of HOFs, including synthesis methods, hydrogen bonding motifs, recent advancements, and potential applications, offering valuable guidance for further exploration in this dynamic field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
