4.2 Article

Hematological, biochemical and histopathological changes in Caspian brown trout (Salmo trutta caspius Kessler, 1877) following exposure to sublethal concentrations of chlorpyrifos

Journal

TOXIN REVIEWS
Volume 36, Issue 1, Pages 73-79

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/15569543.2016.1230631

Keywords

Caspian trout; hematology; biochemical plasma profile; histology

Categories

Funding

  1. Iranian Fisheries Science Research Institute (IFSRI) (Tehran, Iran)
  2. Ministry of Education, Youth and Sports of the Czech Republic [CZ.1.05/2.1.00/01.0024, LO1205]

Ask authors/readers for more resources

The main objective of this study was to survey the acute and sublethal effect of chlorpyrifos (CPF) on Caspian brown trout (Salmo trutta caspius). Toxicity tests were performed for the determination of 96h median lethal concentration (96hLC50). For this purpose, nominal concentrations of CPF including 0.0125, 0.025, 0.05, 0.1, 0.2 and 0.3mgL(-1). The 96hLC50 value of CPF was 0.026mgL(-1). The sublethal effect was determined on the basis of acute toxicity, hematological effects, biochemical plasma profile, behavioral and histopathological changes. The experimental group exposed to CPF at nominal concentration of 0.0026mgL(-1) (10% 96hLC50) for 30 days showed significant changes in hematological and biochemical profiles and caused histopathological changes in liver, gill and kidney. Based on these data, CPF is acute toxic for Caspian trout.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.2
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Review Immunology

A global survey in the developmental landscape of possible vaccination strategies for COVID-19

Amin Gasmi, Shvetha Srinath, Maryam Dadar, Lyudmila Pivina, Alain Menzel, Asma Gasmi Benahmed, Salvatore Chirumbolo, Geir Bjorklund

Summary: The development of COVID-19 vaccines has been regulated to ensure an effective approach. Numerous vaccines have reached different stages of testing, and platforms such as nucleic acid vaccines show promise in terms of availability and safety. Approved vaccines come from various countries, and distribution is a key challenge. Additionally, research has found a potential link between the Bacillus Calmette-Gue ' rin (BCG) vaccination program and lower disease severity.

CLINICAL IMMUNOLOGY (2022)

Review Infectious Diseases

The perspective of antibiotic therapeutic challenges of brucellosis in the Middle East and North African countries: Current situation and therapeutic management

Gamal Wareth, Maryam Dadar, Haytham Ali, Mahmoud E. R. Hamdy, Ahmad M. Al-Talhy, Ahmed R. Elkharsawi, Ashraf A. Abd El Tawab, Heinrich Neubauer

Summary: Brucellosis is common in Middle Eastern and North African countries, affecting both humans and animals. The majority of cases are caused by Brucella melitensis and Brucella abortus, and although some antibiotic resistance has been reported, most strains are still susceptible to recommended treatment regimens.

TRANSBOUNDARY AND EMERGING DISEASES (2022)

Article Immunology

Safety and Efficacy of Combined Intramuscular/Intranasal RAZI-COV PARS Vaccine Candidate Against SARS-CoV-2: A Preclinical Study in Several Animal Models

Seyed Reza Banihashemi, Ali Es-haghi, Mohammad Hossein Fallah Mehrabadi, Mojtaba Nofeli, Ali Rezaei Mokarram, Alireza Ranjbar, Mo Salman, Monireh Hajimoradi, Seyad Hossein Razaz, Maryam Taghdiri, Mohsen Bagheri, Maryam Dadar, Zuhair Mohammad Hassan, Mohammad Eslampanah, Zahra Salehi Najafabadi, Mohsen Lotfi, Akbar Khorasani, Fereidoon Rahmani

Summary: Iran has developed a recombinant protein-based vaccine for COVID-19, which has been proven safe and effective in animal studies. The vaccine stimulates the production of neutralizing antibodies and shows no lung pathology caused by SARS-CoV-2.

FRONTIERS IN IMMUNOLOGY (2022)

Review Food Science & Technology

The prevalence of camel brucellosis and associated risk factors: a global meta-epidemiological study

Maryam Dadar, Sharaf S. Omar, Youcef Shahali, Yadolah Fakhri, Jacques Godfroid, Amin Mousavi Khaneghah

Summary: Camel brucellosis caused by Brucella abortus and Brucella melitensis is a widespread and critical zoonotic infection that negatively impacts dairy and meat products. This meta-analysis investigated the global prevalence of Brucella spp. in camels and identified various risk factors. The overall prevalence of camel brucellosis was found to be 9.23%, with significant variations between different regions and factors such as sex, herd size, age, and mixed rearing. The study highlights the importance of control and surveillance measures in preventing the spread of brucellosis among camel herds.

QUALITY ASSURANCE AND SAFETY OF CROPS & FOODS (2022)

Article Fisheries

Effects of dietary Lactobacillus casei on the immune, growth, antioxidant, and reproductive performances in male zebrafish (Danio rerio)

Roghieh Safari, Mohammad Reza Imanpour, Seyed Hossein Hoseinifar, Mehwish Faheem, Maryam Dadar, Hien Van Doan

Summary: The study demonstrated that probiotics significantly increased protein, globulin, and lysozyme levels in fish, and also upregulated the expression of growth, immunity, and reproduction-related genes. However, the effect on genes related to antioxidant activity was not significant.

AQUACULTURE REPORTS (2022)

Article Microbiology

Genetic Polymorphisms in MicroRNA-196a2 and the Risk of Human Abortion Related to Mycoplasma hominis

Zahra Ivani, Masoumeh Bagheri, Azadeh Zahmatkesh, Maryam Dadar

Summary: This study aimed to investigate the relationship between miRNA196a-2 gene polymorphism and Mycoplasma hominis infection in human abortion. The results showed a significant increase in the proportion of M. hominis infection in women with abortion compared to those without abortion. There was a significant difference in the frequency of miRNA196a-2 genotypes between women with recurrent pregnancy loss (RPL) and those with one abortion, indicating a possible association between miRNA196a-2 genotypes and RPL.

CURRENT MICROBIOLOGY (2022)

Article Biochemical Research Methods

Development of an in-house Indirect ELISA for detection of bovine viral diarrhoea virus antibodies in bovine sera

Anahita Emadi, Lida Abdolmohammadi Khiav, Mohsen Lotfi, Sina Soleimani, Maryam Dadar

Summary: Bovine viral diarrhoea virus (BVDV) infection is a widespread animal disease that causes various health issues. The current gold standard method for detecting BVDV has limitations, leading to the development of an in-house ELISA system with high accuracy and reliability.

JOURNAL OF VIROLOGICAL METHODS (2022)

Article Microbiology

Determination of Virulence-Associated Genes and Antimicrobial Resistance Profiles in Brucella Isolates Recovered from Humans and Animals in Iran Using NGS Technology

Maryam Dadar, Saeed Alamian, Hanka Brangsch, Mohamed Elbadawy, Ahmed R. Elkharsawi, Heinrich Neubauer, Gamal Wareth

Summary: This study investigated antimicrobial resistance (AMR) and virulence-associated factors in Brucella isolates from humans and animals in Iran. B. melitensis was the most common species, while B. abortus was isolated from only one human case. The isolates showed intermediate or resistant phenotype patterns for certain antibiotics. Whole genome sequencing (WGS) identified several virulence-associated genes, but failed to determine classical AMR genes. The findings suggest a need for further investigation into the proteomic and transcriptomic levels of phenotypic resistance mechanisms.

PATHOGENS (2023)

Article Microbiology

Antibiotic Susceptibility, Biofilm-Forming Ability, and Prevalence of Extended-Spectrum Beta-Lactamase (ESBL)- and Biofilm-Associated Genes Among Klebsiella pneumoniae Isolates from Hospitalized Patients in Northwest of Iran

Bahman Mirzaei, Aida Ebrahimi, Shima Keshavarzi, Siamak Hydarzadeh, Farzad Badmasti, Maryam Dadar, Narges Moradi

Summary: Klebsiella pneumoniae is a global opportunistic bacterium with high prevalence and antimicrobial resistance. A study was conducted on 104 K. pneumoniae isolates to determine their biofilm-forming capability, susceptibility to antibiotics, and presence of extended-spectrum beta-lactamase (ESBL) genes. The highest resistance rate was observed against ampicillin (100.0%). Among the isolates, 50.0% were multi-drug resistant (MDR), 29.8% were extensively drug resistant (XDR), and 40.4% were ESBL producers. Biofilm-forming isolates showed significantly higher antimicrobial resistance compared to non-biofilm formers (P < 0.05).

CURRENT MICROBIOLOGY (2023)

Article Agriculture, Dairy & Animal Science

Evaluation of serological diagnostic tests for bovine brucellosis in dairy cattle herds in an endemic area: a multicenter study

Saeed Alamian, Karim Amiry, Akram Bahreinipour, Afshar Etemadi, Ali Reza Yousefi, Maryam Dadar

Summary: The aim of this study was to identify and compare the seroprevalence of brucellosis among dairy cattle farms using different serological tests. Results showed that I-ELISA had higher specificity and sensitivity compared to RBPT and SAT, and could significantly decrease non-specific reaction, making it a more accurate diagnostic tool for brucellosis in endemic areas.

TROPICAL ANIMAL HEALTH AND PRODUCTION (2023)

Review Infectious Diseases

The Impact of Tetracycline Pollution on the Aquatic Environment and Removal Strategies

Yernar Amangelsin, Yuliya Semenova, Maryam Dadar, Mohamad Aljofan, Geir Bjorklund

Summary: Tetracycline, a widely used antibiotic, has become a serious threat to the environment due to overuse and weak degradation ability. It accumulates in the food chain, causing toxicity to microbial communities, promoting antibiotic resistance, and disrupting human intestinal flora.

ANTIBIOTICS-BASEL (2023)

Article Public, Environmental & Occupational Health

Whole-genome sequencing for genetic diversity analysis of Iranian Brucella spp. isolated from humans and livestock

Maryam Dadar, Hanka Brangsch, Saeed Alamian, Heinrich Neubauer, Gamal Wareth

Summary: Brucellosis is a common zoonotic disease in the Middle East, causing economic losses to the livestock industry and posing a great public health concern. This study analyzed the genetic diversity and distribution of Brucella spp. in Iran using whole genome sequencing technology. The results revealed a close relationship between Iranian strains and strains from neighboring and Middle East countries, emphasizing the importance of brucellosis control measures in Iran.

ONE HEALTH (2023)

Article Multidisciplinary Sciences

Shedding rate of Brucella spp. in the milk of seropositive and seronegative dairy cattle

Faranak Abnaroodheleh, Anahita Emadi, Shojaat Dashtipour, Tariq Jamil, Amin Mousavi Khaneghah, Maryam Dadar

Summary: A cross-sectional study in industrial dairy cattle farms in Iran revealed the presence of Brucella spp., including Brucella abortus and Brucella melitensis, in the Alborz and Tehran provinces. The seroprevalence of brucellosis in these farms was significant, and the shedding of Brucella in the milk of seropositive cows posed a serious risk of transmission to humans. Therefore, comprehensive bacteriological and serological tests, including analysis of blood and milk samples, should be conducted in order to control the spread of the disease.

HELIYON (2023)

Article Veterinary Sciences

Serological, cultural, and molecular analysis of Brucella from Buffalo milk in various regions of Iran

Maryam Dadar, Akram Bahreinipour, Saeed Alamian, Ali Reza Yousefi, Karim Amiri, Faranak Abnaroodheleh

Summary: This study aimed to determine the prevalence of Brucella in buffalo milk samples in Iran using serological, molecular, and cultural analyses. The study found positive results for the presence of Brucella DNA in various provinces of Iran, with the AMOS PCR method showing significantly higher sensitivity compared to the milk ring test agglutination test and milk sample culture.

VETERINARY RESEARCH COMMUNICATIONS (2023)

Review Public, Environmental & Occupational Health

Safety concerns and potential hazards of occupational brucellosis in developing countries: a review

Maryam Dadar, Ramin Tabibi, Saeed Alamian, Yohama Caraballo-Arias, Ezra Jonathan Mrema, Jane Mlimbila, Sashikala Chandrasekar, Kenesh Dzhusupov, Cholpon Sulaimanova, Lyailya Zh Alekesheva, Smagul A. Manar, Karlygash K. Toguzbayeva, Aseni Wickramatillake, Bahman Mirzaei

Summary: This review highlights the risk factors associated with brucellosis among different occupational groups and emphasizes the need for a One Health policy to evaluate the complex challenges of brucellosis. However, implementing One Health strategies in developing countries has proven to be challenging.

JOURNAL OF PUBLIC HEALTH-HEIDELBERG (2023)

No Data Available