Article
Medicine, General & Internal
Min Kyung Jung, Sang Young Lee, Jeong Min Ko, Soo-Ah Im
Summary: The aim of this study was to determine whether the glycemic control status influenced radiological manifestations in patients with pulmonary tuberculosis (PTB), particularly in terms of bronchial erosive changes. The study found that the uncontrolled diabetes mellitus (DM) group displayed a higher frequency of cavitation and bronchial erosion, whereas the controlled DM group showed similar frequencies to the non-DM group.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Maria B. Arriaga, Mariana Araujo-Pereira, Beatriz Barreto-Duarte, Betania Nogueira, Maria Vitoria C. N. S. Freire, Artur T. L. Queiroz, Moreno M. S. Rodrigues, Michael S. Rocha, Alexandra B. Souza, Renata Spener-Gomes, Anna Cristina C. Carvalho, Marina C. Figueiredo, Megan M. Turner, Betina Durovni, Jose R. Lapa-E-Silva, Afranio L. Kritski, Solange Cavalcante, Valeria C. Rolla, Marcelo Cordeiro-Santos, Timothy R. Sterling, Bruno B. Andrade
Summary: This study suggests that diabetes is associated with unfavorable treatment outcomes and increased mortality in patients with tuberculosis in Brazil. Interventions to improve tuberculosis treatment outcomes in patients with diabetes are necessary.
JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Julie Copelyn, Brian Eley, Helen Cox, Lesley Workman, Keertan Dheda, Mark P. Nicol, Heather J. Zar
Summary: In children treated for pulmonary tuberculosis, symptoms resolved rapidly while signs resolved more slowly. The pattern and timing of resolution of symptoms and signs cannot distinguish children with pulmonary tuberculosis from those with other lower respiratory tract infections.
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
(2022)
Article
Clinical Neurology
Ruwei Ou, Qianqian Wei, Yanbing Hou, Lingyu Zhang, Kuncheng Liu, Junyu Lin, Zheng Jiang, Wei Song, Bei Cao, Huifang Shang
Summary: In patients with Parkinson's disease, poorly controlled diabetes mellitus is an independent risk factor for motor progression, emphasizing the importance of adequate diabetes control in PD patients.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2021)
Article
Public, Environmental & Occupational Health
Mariana Araujo-Pereira, Betania M. F. Nogueira, Renata Spener-Gomes, Anna C. C. Carvalho, Flavia Marinho Sant'Anna, Marina C. Figueiredo, Megan M. Turner, Afranio L. Kritski, Marcelo Cordeiro-Santos, Valeria C. Rolla, Timothy R. Sterling, Bruno B. Andrade, Alice M. S. Andrade, Vanessa Nascimento, Juan Manuel Cubillos-Angulo, Hayna Malta-Santos, Jessica Reboucas-Silva, Saulo R. N. Santos, Andre Ramos, Pedro Brito, Carolina A. S. Schmaltz, Alysson G. Costa, Leandro Sousa Garcia, Brenda K. de Sousa Carvalho, Bruna P. de Loiola, Adriano Gomes-Silva, Francine P. Ignacio, Maria C. Lourenco, Elisangela C. Silva, Mayla Mello, Alexandra B. Souza, Beatriz Barreto-Duarte, Michael S. Rocha, Aline Benjamin, Adriana S. R. Moreira, Jamile G. de Oliveira, Solange Cavalcante, Betina Durovni, Jose R. Lapa-e-Silva
Summary: This study assessed whether the severity of anemia in TB patients prior to treatment was a risk factor for an unfavorable outcome. The results showed that moderate/severe anemia was associated with death, indicating the need for close monitoring of these patients.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2023)
Article
Respiratory System
Findra Setianingrum, Anna Rozaliyani, Robiatul Adawiyah, Ridhawati Syam, Mulyati Tugiran, Cut Yulia Sari, Finny Nandipinto, Johannes Ramnath, Arief Riadi Arifin, Diah Handayani, Erlina Burhan, Martin C. Rumende, Retno Wahyuningsih, Riina Rautemaa-Richardson, David W. Denning
Summary: CPA is a common differential diagnosis in Indonesian patients being treated for possible or proven TB. Limited access to diagnostic tests and imaging may be obstacles in establishing a CPA diagnosis.
Article
Medicine, General & Internal
Frank Kloprogge, Ibrahim Abubakar, Hanif Esmail, Vanessa Hack, Heinke Kunst, Timothy D. McHugh, Mahdad Noursadeghi, Julian Surey, Simon Tiberi, Marc Lipman
Summary: This observational cohort study aims to investigate the correlations between different antibiotic exposures and sputum bacillary load and host immune response in tuberculosis patients, with the goal of identifying a combined biomarker predictive of cure. The study will involve quantifying antibiotic plasma concentrations, sputum bacillary load, and host blood transcriptomic data, and analyzing them using mixed-effects models to predict microbiological cure and relapse-free outcomes. The results will be disseminated through publication, presentation, and engagement with organizations developing novel anti-TB treatments.
Article
Medicine, General & Internal
Victor Williams, Alinda Vos, Kennedy Otwombe, Diederick E. Grobbee, Kerstin Klipstein-Grobusch
Summary: This study aims to describe the epidemiology of diabetes mellitus-tuberculosis comorbidity in Eswatini and identify best practices for integrating care for non-communicable diseases into TB services.
Article
Respiratory System
Rebecca Nightingale, Beatrice Chinoko, Maia Lesosky, Sarah J. Rylance, Bright Mnesa, Ndaziona Peter Kwanjo Banda, Elizabeth Joekes, Stephen Bertel Squire, Kevin Mortimer, Jamilah Meghji, Jamie Rylance
Summary: This study described the symptoms and lung function changes of Malawian adults up to 3 years following pulmonary tuberculosis (PTB) treatment completion, finding that a third of PTB survivors experienced ongoing respiratory symptoms and abnormal spirometry (with accelerated FEV1 decline). Effective interventions are needed to improve the care of this group of patients.
Article
Immunology
Yunfei Wei, Shiting Tang, Zhouhua Xie, Yaoqin He, Yunli Zhang, Yiju Xie, Shijian Chen, Liuyu Liu, Yayuan Liu, Zhijian Liang
Summary: This study explores the clinical features and underlying pathogenesis of pulmonary tuberculosis-related ischemic stroke (TBRIS) in patients with active pulmonary tuberculosis. The study finds that most TBRIS patients experienced ischemic stroke events within 3 months after tuberculosis diagnosis. The study also identifies several independent risk factors for TBRIS and establishes an index that helps clinicians identify high-risk TBRIS patients among pulmonary tuberculosis patients.
JOURNAL OF INFLAMMATION RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Zheyuan Wu, Liping Lu, Yong Li, Jing Chen, Zurong Zhang, Chenxi Ning, Zheng'an Yuan, Qichao Pan, Xin Shen, Wenhong Zhang
Summary: This prospective cohort study evaluated the effects of a reminder app and smart pillbox on tuberculosis treatment outcomes compared to standard care in Shanghai, China. The study found that both the reminder app and smart pillbox interventions improved treatment success rates, indicating their potential as effective tools to support tuberculosis patients.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Immunology
Jeremi Swanepoel, Gert van Zyl, Anneke C. Hesseling, Sarah M. Johnson, David A. J. Moore, James A. Seddon
Summary: This study found a high prevalence of sensitization to human cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) among adolescents in a high-tuberculosis-burden setting. Higher HCMV IgG titers were associated with pulmonary tuberculosis in adolescents.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Article
Infectious Diseases
Panyachot Buasroung, Tananchai Petnak, Prapaipim Liwtanakitpipat, Sasisopin Kiertiburanakul
Summary: The prevalence of diabetes mellitus (DM) among tuberculosis (TB) patients was unexpectedly high in this study, and TB patients with DM had unfavorable outcomes compared to those without DM.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Review
Microbiology
Alexandra J. Zimmer, Federica Lainati, Nathaly Aguilera Vasquez, Carole Chedid, Sean McGrath, Andrea Benedetti, Emily MacLean, Morten Ruhwald, Claudia M. Denkinger, Mikashmi Kohli
Summary: This study systematically reviewed biomarkers for monitoring treatment of pulmonary tuberculosis in adults and found that C-reactive protein, interleukin-6, interferon gamma-induced protein 10, and tumor necrosis factor alpha showed a decrease during the early stage of treatment, suggesting their potential as biomarkers. However, the heterogeneity in study design and reporting poses a major challenge in evaluating novel biomarkers.
JOURNAL OF CLINICAL MICROBIOLOGY
(2022)
Article
Infectious Diseases
Yanwan Shangguan, Wanru Guo, Xuewen Feng, Yunzhen Shi, Xiaomeng Li, Zhifen Pan, Ming Hu, Jichan Shi, Cheng Ding, Jiafeng Xia, Wenjuan Hu, Zhongkang Ji, Chengjie Zhao, Yuecui Li, Zebao He, Lingxiao Jin, Xiaodong Tao, Xinming Zhu, Xiaoqiang Zhang, Qun Song, Yuyin Zhu, Lin Zheng, Xiuyuan Jin, Shujuan Huang, Liangxiu Jiang, Yuping Wang, Tiantian Wu, Dan Cao, Ying Zhang, Lanjuan Li, Kaijin Xu
Summary: This study demonstrated that oral faropenem regimen can be used for the treatment of tuberculosis with fewer adverse events.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Correction
Otorhinolaryngology
Sung Jin Min, Hyun Kang, Kyung Soo Kim, Hyun Jin Min
AURIS NASUS LARYNX
(2023)
Article
Surgery
Han-Wool Choung, Young-Jun Choi, Hyun Kang, Ui-Lyong Lei
Summary: The present study reports a rare case series of subcutaneous emphysema with or without pneumomediastinum and pneumothorax after orthognathic and facial bone contouring surgery, compares their clinical and radiologic findings, and suggests precautions.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Article
Surgery
Tae Young Park, Hyun Kang, Geun Joo Choi, Hyoung-Chul Oh
Summary: This study analyzed 12 studies and found that aggressive hydration can significantly reduce the incidence of pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). However, the effect of aggressive hydration is not significant in high-risk populations and patients with moderate-severe pancreatitis, suggesting the need for further research.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2023)
Review
Health Care Sciences & Services
Hyo Jin Kim, EunJin Ahn, Geun Joo Choi, Hyun Kang
Summary: This study compared the efficacy of perioperative administration of palonosetron and ramosetron in preventing postoperative nausea and vomiting (PONV). A total of 17 randomized controlled trials were included in the analysis, and the results showed that palonosetron was more effective than ramosetron in reducing vomiting and late vomiting. However, there were no significant differences in nausea, PONV, complete response, use of antiemetics, and adverse effects between the two drugs. Subgroup analysis showed that palonosetron was superior to ramosetron in early PON, late PON, overall POV, and use of rescue antiemetics when administered early, while ramosetron was superior in early PON when administered late. The prophylactic administration of palonosetron was more effective than ramosetron in preventing retching and late POV. No significant differences in PONV prevention were found between the two drugs in this meta-analysis. Further studies are needed to confirm these findings.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
SeungYoung Lee, Min Kyoung Kim, EunJin Ahn, YongHun Jung
Summary: This retrospective study compared mortality and short-term complications in patients undergoing total knee arthroplasty (TKA) under general anesthesia or regional anesthesia. The study found that regional anesthesia was associated with lower rates of major complications such as myocardial infarction and acute renal failure, as well as lower admission to the intensive care unit and medical costs.
Review
Medicine, General & Internal
Hyoung-Chul Oh, Hyun Kang
Summary: Preprints are preliminary research reports that have not yet been peer-reviewed and have been widely adopted to promote timely research dissemination. While they provide valuable resources, they also raise concerns about unsupported conclusions and the integrity of journals.
KOREAN JOURNAL OF INTERNAL MEDICINE
(2023)
Editorial Material
Telecommunications
Shiwen Mao
IEEE TRANSACTIONS ON COGNITIVE COMMUNICATIONS AND NETWORKING
(2023)
Article
Orthopedics
Kwang-Sup Song, Jeongik Lee, Dae Woong Ham, Chan-Woo Jung, Hyun Kang, Seung Won Park, Dong-Gune Chang, Youngbae B. Kim
Summary: This retrospective observational study investigated the impact of plating on postoperative serial segmental motion and its correlation with clinical outcomes in single-level anterior cervical discectomy and fusion (ACDF) for up to 1 year. The results showed that using cervical plating significantly decreases postoperative serial segmental motion and is correlated with decreased neck pain, particularly at 3 and 6 months postoperatively. Therefore, the authors recommend the use of plating in single-level ACDF for better early clinical outcomes.
ASIAN SPINE JOURNAL
(2023)
Review
Health Care Sciences & Services
Myeongjong Lee, Cheol Lee, Junsung Lim, Hyungtae Kim, Yoo-Shin Choi, Hyun Kang
Summary: This systematic review and meta-analysis aimed to compare the perioperative outcomes of peripheral nerve blocks (PNBs) and spinal anesthesia (SA) in elective foot and ankle surgery. The study found that SA was associated with shorter block performance times, faster onset and shorter duration of sensory and motor blocks, higher postoperative analgesic requirements, and lower systolic blood pressure at 30 min compared to PNBs.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Review
Health Care Sciences & Services
Min Kyoung Kim, Geun Joo Choi, Kyung Seo Oh, Sang Phil Lee, Hyun Kang
Summary: The study evaluated the accuracy and effectiveness of the analgesia nociception index (ANI) in assessing intra- and post-operative pain during general anesthesia. The results showed that ANI can predict intra- and post-operative pain, reduce the use of intra-operative opioids, and aid in post-operative pain management.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Shin Hye Yoo, Yejin Kim, Wonho Choi, Jeongmi Shin, Min Sun Kim, Hye Yoon Park, Bhumsuk Keam, Jae -Joon Yim
Summary: This study aimed to explore the various ethical issues referred to clinical ethics support after the implementation of new legislation on hospice palliative care and end-of-life decision-making in Korea in 2018. The most frequent ethical issues identified were goals of care/treatment, decision-making, relationship, and end-of-life issues. The findings highlight the importance of further research on ethical issues and the implementation of clinical ethics support in multiple healthcare centers.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Review
Anesthesiology
Je Jin Lee, Geun Joo Choi, Won Jun Lee, Sang Bong Choi, Hyun Kang
Summary: This study investigated the effectiveness of heated-humidified breathing circuit (HHBC) in maintaining the core temperature of patients receiving mechanical ventilation under general anesthesia. The analysis of 18 randomized controlled trials revealed that patients with HHBC had significantly higher core temperature at the end of surgery compared to those without any device or with heat and moisture exchanger. This suggests that HHBC can be used as an effective supplemental device to maintain intraoperative core temperature.
KOREAN JOURNAL OF ANESTHESIOLOGY
(2023)
Article
Medicine, General & Internal
Geun Joo Choi, Hyun Kang, Oh Haeng Lee, Ji Wung Kwon
Summary: This study aimed to compare the analgesic properties of immature and mature Rubus occidentalis extracts (iROE and mROE) using a rat model of postoperative pain. The results showed that iROE had better analgesic and anti-inflammatory effects compared to mROE. The analgesic activity of iROE may be associated with α2-adrenergic and opioid receptors.
MEDICINA-LITHUANIA
(2023)
Article
Anesthesiology
Eunjin Ahn, Hyun Kang
KOREAN JOURNAL OF ANESTHESIOLOGY
(2023)
Article
Critical Care Medicine
Joong-Yub Kim, Jiwon Park, Yunhee Choi, Taek Soo Kim, Nakwon Kwak, Jae-Joon Yim
Summary: This study found that achieving microbiological cure at the end of treatment is associated with longer survival in patients with nontuberculous mycobacterial pulmonary disease.