HDAC4 stabilizes SIRT1 via sumoylation SIRT1 to delay cellular senescence

A Novel Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitor Derivative, N25, Exhibiting Improved Antitumor Activity in both Human U251 and H460 Cells

(2014) Song Zhang et al.   Asian Pacific Journal of Cancer Prevention

PPARα-Sirt1 Complex Mediates Cardiac Hypertrophy and Failure through Suppression of the ERR Transcriptional Pathway

(2011) Shinichi Oka et al.   Cell Metabolism

Sirtuin 1 (SIRT1) Protein Degradation in Response to Persistent c-Jun N-terminal Kinase 1 (JNK1) Activation Contributes to Hepatic Steatosis in Obesity

(2011) Zhanguo Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

(2009) Kathryn Moynihan Ramsey et al.   AGING CELL

Loss of Histone Deacetylase 4 Causes Segregation Defects during Mitosis of p53-Deficient Human Tumor Cells

(2009) B. Cadot et al.   CANCER RESEARCH

The transcription factor ZBP-89 suppresses p16 expression through a histone modification mechanism to affect cell senescence

(2009) Yunpeng Feng et al.   FEBS Journal

HDAC4 Regulates Neuronal Survival in Normal and Diseased Retinas

(2009) B. Chen et al.   SCIENCE

Cellular conditioning with trichostatin A enhances the anti-stress response through up-regulation of HDAC4 and down-regulation of the IGF/Akt pathway

(2008) Fei Chu et al.   AGING CELL

YY1 restrained cell senescence through repressing the transcription of p16

(2008) Xiuli Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

HDAC4 Promotes Growth of Colon Cancer Cells via Repression of p21

(2008) Andrew J. Wilson et al.   MOLECULAR BIOLOGY OF THE CELL

Negative regulation of the deacetylase SIRT1 by DBC1

(2008) Wenhui Zhao et al.   NATURE

DBC1 is a negative regulator of SIRT1

(2008) Ja-Eun Kim et al.   NATURE

HDAC4 represses p21WAF1/Cip1 expression in human cancer cells through a Sp1-dependent, p53-independent mechanism

(2008) D Mottet et al.   ONCOGENE