The ageing human B cell repertoire: a failure of selection?

Age-related aspects of human IgM+ B cell heterogeneity

(2015) Victoria Martin et al.   Annals of the New York Academy of Sciences

Circulating Human CD27−IgA+Memory B Cells Recognize Bacteria with Polyreactive Igs

(2015) Magdalena A. Berkowska et al.   JOURNAL OF IMMUNOLOGY

Ebola Virus Disease among Children in West Africa

(2015)   NEW ENGLAND JOURNAL OF MEDICINE

Ageing of the B-cell repertoire

(2015) Victoria Martin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

(2014) A. Khoder et al.   BLOOD

A review of the evidence to inform pneumococcal vaccine recommendations for risk groups aged 2 years and older

(2014) A. STEENS et al.   EPIDEMIOLOGY AND INFECTION

Plasma cell numbers decrease in bone marrow of old patients

(2014) Theresa Pritz et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Trafficking phenotype and production of granzyme B by double negative B cells (IgG+IgD−CD27−) in the elderly

(2014) Matteo Bulati et al.   EXPERIMENTAL GERONTOLOGY

Vaccines for the Elderly

(2014) Giuseppe Del Giudice et al.   GERONTOLOGY

The aging bone marrow and its impact on immune responses in old age

(2014) Theresa Pritz et al.   IMMUNOLOGY LETTERS

Human lymphocyte repertoires in ageing

(2013) Scott D Boyd et al.   CURRENT OPINION IN IMMUNOLOGY

Effects of Aging, Cytomegalovirus Infection, and EBV Infection on Human B Cell Repertoires

(2013) C. Wang et al.   JOURNAL OF IMMUNOLOGY

Lineage Structure of the Human Antibody Repertoire in Response to Influenza Vaccination

(2013) N. Jiang et al.   Science Translational Medicine

IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients

(2012) S. Weller et al.   BLOOD

Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire

(2012) Sarah L. Rowland et al.   IMMUNOLOGIC RESEARCH

Shaping of Human Germline IgH Repertoires Revealed by Deep Sequencing

(2012) K. Larimore et al.   JOURNAL OF IMMUNOLOGY

Age-Related Changes in Human Peripheral Blood IGH Repertoire Following Vaccination

(2012) Yu-Chang Bryan Wu et al.   Frontiers in Immunology

Vaccination-induced changes in human B-cell repertoire and pneumococcal IgM and IgA antibody at different ages

(2011) Alexander Ademokun et al.   AGING CELL

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

(2011) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Relationship between CD27 Negative and Positive B Cell Populations in Human Peripheral Blood

(2011) Yu-Chang Bryan Wu et al.   Frontiers in Immunology

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

(2010) Y.-C. Wu et al.   BLOOD

B cell repertoire and ageing

(2010) Deborah K Dunn-Walters et al.   CURRENT OPINION IN IMMUNOLOGY

Older Adults Have a Low Capacity To Opsonize Pneumococci Due to Low IgM Antibody Response to Pneumococcal Vaccinations

(2010) Saeyoung Park et al.   INFECTION AND IMMUNITY

Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes

(2010) Stephanie C. Degner-Leisso et al.   SEMINARS IN IMMUNOLOGY

Human Marginal Zone B Cells

(2009) Jean-Claude Weill et al.   Annual Review of Immunology

Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+B cells and the dynamics of memory B cell generation

(2009) Marc Seifert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A double-negative (IgD−CD27−) B cell population is increased in the peripheral blood of elderly people

(2009) Giuseppina Colonna-Romano et al.   MECHANISMS OF AGEING AND DEVELOPMENT

B-cell diversity decreases in old age and is correlated with poor health status

(2008) Kate L. Gibson et al.   AGING CELL

BAFF and the plasticity of peripheral B cell tolerance

(2008) Jason E Stadanlick et al.   CURRENT OPINION IN IMMUNOLOGY

T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+B cells

(2008) Ferenc A. Scheeren et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY

Characterization of rotavirus specific B cells and their relation with serological memory

(2008) Olga Lucía Rojas et al.   VIROLOGY