Article
Chemistry, Applied
Alexey A. Pakhomov, Eleonora E. Kim, Yuriy N. Kononevich, Dmitriy S. Ionov, Margarita A. Maksimova, Veronika B. Khalchenia, Eugene G. Maksimov, Anton A. Anisimov, Olga I. Shchegolikhina, Vladimir I. Martynov, Aziz M. Muzafarov
Summary: A series of multifluorophore compounds were synthesized by linking different numbers of BODIPY residues, which exhibited characteristic photophysical effects. Increasing the number of fluorophores led to a significant increase in molar extinction coefficient and broadening of fluorescence emission bands, but a decrease in fluorescence quantum yield due to aggregation-caused quenching.
Article
Spectroscopy
Felix Y. Telegin, Yuriy S. Marfin
Summary: A simple semiempiric phenomenological approach is developed to quantify the solvent effect on the absorption and emission properties of BODIPYs, based on a new rule describing the linear relationship between the difference and sum of absorption and emission wavenumbers. The approach demonstrates high reliability and advantages compared to traditional methods for analyzing solvatochromism in selected BODIPYs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Polymer Science
Zhaoqun Pan, Mianfeng Chen, Keling Zeng, Yingzi Kang
Summary: In this study, a novel cyclotetrasiloxane modified with epoxy resin was synthesized and applied as LED packaging materials. The cured products showed high light transmittance, strong thermal stability, suitable hardness, and low water absorption, with enhanced flexibility due to the introduction of epoxy groups. The results suggest that the epoxy-modified silicone materials have potential applications in LED packaging.
Article
Polymer Science
Aleksei I. Ryzhkov, Fedor V. Drozdov, Georgij V. Cherkaev, Aziz M. Muzafarov
Summary: In this work, carbosilane dendrons were synthesized based on the natural terpenoid limonene, allowing the preservation of its double bond while acting as the growth center. The selectivity of hydrosilylation and hydrothiolation reactions resulted in the formation of carbosilane dendrons with specific structures. This synthesis method opens up wide possibilities for obtaining various macromolecules.
Article
Chemistry, Physical
A. A. Pakhomov, A. V. Efremova, M. A. Maksimova, Yu. N. Kononevich, D. S. Ionov, N. O. Dubinets, V. I. Martynov, A. M. Muzafarov, M. V. Alfimov
Summary: The photophysical properties of functional distyryl derivatives of dipyrrometheneboron difluoride (BODIPY) in different solvents were investigated. It was found that these compounds showed similar absorption and fluorescence spectra in all solvents, which are characteristic of the distyryl derivatives of BODIPY. The slight bathochromic shifts of the spectra with increasing solvent polarity and insignificant changes in rate constants of radiative and nonradiative processes indicate that the S-1 states are of (pi,pi*) type. These dyes can be utilized for visualizing biological processes.
HIGH ENERGY CHEMISTRY
(2023)
Article
Chemistry, Organic
Elizaveta A. Manokhina, Anton A. Anisimov, Fedor V. Drozdov, Rinat S. Tukhvatshin, Alexander S. Peregudov, Svetlana A. Aksenova, Aziz M. Muzafarov
Summary: This paper describes the synthesis of a storage-stable organosilicon modifier with a dioxaborolane-protecting group. It exhibits high reactivity and selective anti-Markovnikov addition in hydrosilylation reactions, yielding various structures of siloxanes. Deprotection of the modifier and its siloxane derivatives can be achieved under mild conditions using water, with yields up to 96%. The equilibrium between organosilicon derivatives of phenylboronic acids and cyclic six-membered boroxines was confirmed by H-1 NMR spectroscopy and X-ray diffraction analysis. The application of siloxane derivatives of phenylboronic acids in Suzuki-Miyaura and Chan-Lam cross-coupling reactions was also studied. All synthesized compounds were characterized by NMR (H-1, B-11, C-13, and Si-29), IR spectroscopy, and high-resolution mass spectrometry.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Polymer Science
Takahiro Kawatsu, Keita Fuchise, Katsuhiko Takeuchi, Jun-Chul Choi, Kazuhiko Sato, Kazuhiro Matsumoto
Summary: This study successfully synthesized macrocyclic polysiloxanes with unique structures, and then transformed them into novel organofunctional polysiloxanes, maintaining the macrocyclic and spiro structures.
Article
Chemistry, Analytical
Caroline Ndung'u, Daniel J. LaMaster, Simran Dhingra, Nathan H. Mitchell, Petia Bobadova-Parvanova, Frank R. Fronczek, Noemie Elgrishi, Maria da Graca H. Vicente
Summary: This study compared the properties of BODIPY dyes with pyridyl moiety, and found that the introduction of 2,6-dichloro groups can enhance their fluorescence quantum yield in organic solvents. 2,6-dichloro-meso-(2- and 3-pyridinium)-BODIPYs were identified as the most promising for sensing applications.
Article
Chemistry, Analytical
Mehmet Oguz, Serkan Erdemir, Sait Malkondu
Summary: This article introduces a ratiometric fluorescent probe based on the ICT mechanism for detecting hydrazine. The probe exhibits high sensitivity and selectivity, with the ability to detect hydrazine within approximately 2.0 minutes. Additionally, the probe demonstrates solvatochromism, indicating a high sensitivity to medium polarity. By constructing a portable smartphone platform, the probe is successfully applied to water samples, bioimaging, and environmental monitoring, suggesting significant potential applications.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Serkan Erdemir, Sait Malkondu
Summary: Environment-sensitive fluorescent dyes have become important tools in fluorescence detection and imaging, particularly for polarity-responsive sensors. The novel isophorone and phenylamine dye (IPA) demonstrated recognition ability for Al3+ and solvatofluorchromic properties in various organic solvents. The dye’s turn-on NIR emissive and colorimetric response towards Al3+ was significant, and it could successfully determine water content in commercial alcoholic solutions.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Physical
Mitsuhiko Morisue, Miho Kawanishi, Takahiro Kusukawa
Summary: The quadrupolar porphyrin-BODIPY-porphyrin array displayed moderate negative solvatochromism, where the elastic phenyl groups facilitated solubility in nonpolar solvents. The thermodynamic analyses revealed a small entropy change, driven mainly by enthalpy change, upon double-strand formation in nonpolar solvent. The solvent polarity effect on electronic spectra and thermodynamic analyses suggested a decrease in charge-transfer character with double-strand formation.
Article
Chemistry, Multidisciplinary
Xinyue Wang, Sophie Bou, Andrey S. Klymchenko, Nicolas Anton, Mayeul Collot
Summary: Nanoemulsions are water-dispersed oil droplets that exhibit impressive fluorescent brightness and biocompatibility, with their properties greatly influenced by the nature of lipid anchor and oil used for emulsification. New BODIPY conjugates were synthesized to enhance the brightness of Nanoemulsions, showing improved physical and photophysical properties.
Article
Chemistry, Analytical
Jin-Ye Lu, Jia-Xin Wang, Yang Li, Qiu-Yun Chen, Ling-Ling Qu, Su-Ci Meng, Ming-Qi Wang
Summary: Phthalates esters (PAEs) have been detected using a BODIPY fluorescent dye, forming nano fluorescent dyes upon binding, and the binding ratio with DBP affects the detection sensitivity of PAEs. This study suggests that attenuating the isomerization of water caged BODIPY dyes could be a potential strategy for the development of turn-on fluorescence sensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Kartik Dutta, Richa Agrawal, A. P. Wadawale, Sunita Gamre, Soumyaditya Mula
Summary: A new class of dual state emissive dyes based on beta-carboline boron complexes was synthesized, which exhibit emission in both solution and the solid state. The fluorescence properties were modulated by substituents at the boron center and the C-3 position of the beta-carboline moiety. X-ray crystallography and theoretical calculations were used to understand the photophysical properties of the dyes. The ease of synthesis, dual state emission, and reversible electrochemical properties make these dyes valuable for future materials development.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Organic
Kang Li, Honghan Ji, Zeren Yang, Wenzeng Duan, Yudao Ma, Houting Liu, Huaiwei Wang, Shuwen Gong
Summary: The design and synthesis of a new family of CPL-active BF2 complexes were described in this work, which display aggregation-amplified CPL with moderate dissymmetry factors values and moderate quantum yields both in solution and in the solid state. These photophysical properties were rationalized via X-ray diffraction and TD-DFT calculations.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Review
Polymer Science
Kseniya A. Bezlepkina, Sergey A. Milenin, Natalia G. Vasilenko, Aziz M. Muzafarov
Summary: PDMS telechelics are important in both industry and academic research, serving as free-standing materials or as part of copolymers and cross-linked materials. The most commonly used method for preparing PDMS is diorganosiloxane ring-opening polymerization (ROP) with the presence of nucleophilic or electrophilic initiators.
Article
Biochemistry & Molecular Biology
Anastasiia A. Mamaeva, Anastasiya Yu. Frolova, Dmitry L. Kakuev, Vladimir I. Martynov, Sergey M. Deyev, Alexey A. Pakhomov
Summary: It has been demonstrated that using highly homologous plasmids with identical origins of replication and different antibiotic resistance genes allows for high expression of both plasmids in bacteria. However, the level of gene expression and protein production can vary and is mainly determined by the sequence of the genes rather than the incompatibility of the plasmids.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Anastasia S. Belova, Yuriy N. Kononevich, Dmitry S. Ionov, Viacheslav A. Sazhnikov, Alexander D. Volodin, Alexander A. Korlyukov, Pavel V. Dorovatovskii, Mikhail V. Alfimov, Aziz M. Muzafarov
Summary: A series of new DBMBF2 compounds and their methoxy-substituted derivatives linked by flexible diphenylsiloxane linkers of various length have been synthesized. Their structure and optical properties were investigated using different techniques, revealing the emission behavior of the compounds in different solvent environments. The formation of intramolecular excimers was influenced by the polarity of the solvent and the length of the linker. It was observed that emissions close to white light can be achieved in certain solvent environments.
Article
Biochemistry & Molecular Biology
Alexey A. Pakhomov, Anastasia S. Belova, Arevik G. Khchoyan, Yuriy N. Kononevich, Dmitriy S. Ionov, Margarita A. Maksimova, Anastasiya Yu Frolova, Mikhail Alfimov, Vladimir Martynov, Aziz M. Muzafarov
Summary: In this study, a novel compound combining BODIPY dye and DPA was synthesized and utilized as a ratiometric sensor for singlet oxygen, showing promising potential for biomedical applications.
Article
Polymer Science
Alexandra A. Kalinina, Olga B. Gorbatsevich, Nikita G. Yakhontov, Nina V. Demchenko, Nataliya G. Vasilenko, Valentina V. Kazakova, Aziz M. Muzafarov
Summary: The catalyst-free hydrolytic polycondensation of methyltrimethoxysilane under microwave radiation was studied. The effect of molar ratios, radiation power, temperature, and duration of exposure on the reaction was investigated. The use of microwave radiation was shown to enhance the reaction activation, achieving almost complete conversion of the monomer in 5 minutes at 30°C, 20 W, and an MTMS/H2O ratio of 1/3. The optimal radiation power for maximum conversion and MeO-group elimination was found to be in the range of 20-100 W.
Article
Chemistry, Physical
Alexey A. A. Pakhomov, Anna V. V. Efremova, Yuriy N. N. Kononevich, Dmitriy S. S. Ionov, Margarita A. A. Maksimova, Alexander D. D. Volodin, Alexander A. A. Korlyukov, Nikita O. O. Dubinets, Vladimir I. I. Martynov, Anatoly A. A. Ivanov, Aziz M. M. Muzafarov
Summary: Fluorescent dyes that emit/excite in the second near-infrared (NIR-II, 1000-1350 nm) region are gaining attention in bioimaging and diagnostics applications. Dyes with high two-photon absorption cross-section (TPA), like BODIPY derivatives, are of particular interest due to their ability to penetrate deeper into biological tissues and provide better imaging contrast with reduced phototoxicity and photobleaching. This study reports the synthesis and properties of new monomeric and dimeric di-styryl-BODIPY dyes, which exhibit absorption maxima near 625 nm and emit in the range of 600-800 nm (NIR-I, 650-950 nm). The dyes were excited using a femtosecond Cr:Forsterite laser with a wavelength of 1250 nm (NIR-II) and a cooperative effect of TPA was observed for the dimeric di-styryl-BODIPY dyes. These results are significant for their potential applications in bioimaging and photodynamic therapy.
Article
Chemistry, Physical
Anastasia S. Belova, Yuriy N. Kononevich, Dmitriy S. Ionov, Viacheslav A. Sazhnikov, Anton A. Anisimov, Andrey A. Safonov, Nikolay M. Surin, Evgeniya A. Svidchenko, Yury V. Fedorov, Olga I. Shchegolikhina, Aziz M. Muzafarov
Summary: A series of tetrachromophoric systems based on stereoregular tetracyclosiloxanes and dibenzoylmethanatoboron difluoride derivatives have been synthesized and characterized. The photophysical properties of these compounds were investigated using various spectroscopic methods. The synthesized compounds exhibited complex fluorescence behavior with different lifetimes, and showed promising potential for the development of single-emission materials for white illumination.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Aleksei I. Ryzhkov, Fedor V. Drozdov, Georgij V. Cherkaev, Aziz M. Muzafarov
Summary: The synthesis of carbosilane and carbosilane-siloxane dendrons based on limonene, a natural terpene, was previously reported. The regioselective hydrosilylation of limonene was found to occur exclusively at the isoprenyl double bond, allowing for the preparation of carbosilane dendrons with a limonene moiety. In this study, variants for the functionalization of the cyclohexene double bond were presented, enabling the preparation of various macromolecular objects using the resulting dendrons.
APPLIED SCIENCES-BASEL
(2023)
Article
Pharmacology & Pharmacy
Alexander Vasil'kov, Dmitry Migulin, Alexander Naumkin, Ilya Volkov, Ivan Butenko, Alexandre Golub, Vera Sadykova, Aziz Muzafarov
Summary: New hybrid materials combining Ag nanoparticles with a polyaminopropylalkoxysiloxane hyperbranched polymer matrix were prepared. The Ag nanoparticles were synthesized by metal vapor synthesis (MVS) and incorporated into the polymer matrix using metal-containing organosol. The nanocomposites showed antimicrobial activity against Bacillus subtilis and Escherichia coli.
Article
Polymer Science
Kirill Borisov, Alexandra Kalinina, Aleksandra Bystrova, Aziz Muzafarov
Summary: Aerogels are materials with exceptional physical and chemical properties, but their brittleness has limited their applications. By using organosilicon compounds, we have synthesized aerogel-like materials that overcome this limitation.
Article
Chemistry, Multidisciplinary
Dmitry R. R. Streltsov, Kirill M. M. Borisov, Aleksandra A. A. Kalinina, Aziz M. M. Muzafarov
Summary: Silica hollow spheres with a diameter of 100-300 nm and a shell thickness of 8 +/- 2 nm were synthesized using a self-templating amphiphilic polymeric precursor. The elastic properties of these spheres were studied using high-frequency AFM indentation, allowing for visualization of the surface morphology and high-resolution mapping of the mechanical properties. The Young's modulus of the shell material was found to be E = 26 +/- 7 GPa in the elastic regime, while beyond this regime, buckling instability and irreversible deformation of the shell were observed.
Article
Biochemistry & Molecular Biology
Anastasiya Yu. Frolova, Alexey A. Pakhomov, Dmitry L. Kakuev, Anna S. Sungurova, Anastasiya A. Dremina, Elizaveta D. Mamontova, Sergey M. Deyev, Vladimir I. Martynov
Summary: Creating new tools for the early diagnosis and treatment of cancer is crucial in modern medicine. Photodynamic cancer therapy (PDT) has gained attention as a minimally invasive treatment with no acquired resistance. However, PDT comes with undesirable effects on healthy tissues. This study presents the development of a hybrid protein-peptide system that selectively binds and kills cancer cells under a certain pH condition, offering a potential for highly precise photodynamic therapy.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2023)
Article
Polymer Science
Alexander N. Tarasenkov, Maria S. Parshina, Nadezhda A. Tebeneva, Kirill M. Borisov, Galina P. Goncharuk, Vitaliy G. Shevchenko, Sergey A. Ponomarenko, Aziz M. Muzafarov
Summary: The dielectric and mechanical properties of polydimethylsiloxane-based compositions filled with silica and cured with metallosiloxanes were studied. The introduction of silica and formation of metal-siloxane networks significantly improved the dielectric properties of the material. Varying the structure and composition of the metallosiloxanes and the degree of silica filling allowed for effective control of the dielectric parameters. Changing the functionality and length of the rubber chain, as well as the curing rate, provided a wide range of mechanical properties. The cured systems have potential applications as flexible capacitive sensors or actuators.
EXPRESS POLYMER LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Yuriy N. Kononevich, Anastasia S. Belova, Dmitry S. Ionov, Viacheslav A. Sazhnikov, Alexey A. Pakhomov, Mikhail V. Alfimov, Aziz M. Muzafarov
Summary: In this study, a novel dyad connecting boron dipyrromethene and dibenzoylmethanatoboron difluoride was synthesized and its photophysical properties were investigated. The dyad exhibited large pseudo-Stokes' shifts and efficient Forster resonance energy transfer in different solvents. The fluorescence quantum yield of the dyad was lower due to the complex interaction between the fluorophore fragments and the presence of the flexible linker.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Organic
Geeta Devi Yadav, Pooja Chaudhary, Balaram Pani, Surendra Singh
Summary: Chiral transition metal complexes with privileged ligands are efficient catalysts for various asymmetric organic transformations. Transition metal complexes of C1-symmetric pyrrolidine-based ligands have been widely used in asymmetric organic reactions. However, a comprehensive review article on the transition metal complexes of chiral C1-symmetric pyrrolidine-based ligands derived from (L)-proline has not been published.
TETRAHEDRON LETTERS
(2024)
