Journal
STRUCTURE
Volume 24, Issue 4, Pages 495-495Publisher
CELL PRESS
DOI: 10.1016/j.str.2016.03.011
Keywords
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Funding
- Intramural NIH HHS [ZIA BC011460-01] Funding Source: Medline
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BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting this potentially deadly virus. The study also serves as a platform for exploring the basic biology of virion assembly and infectious entry.
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