Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells

Diminished levels of the soluble form of RAGE are related to poor survival in malignant melanoma

(2015) Nikolaus B. Wagner et al.   INTERNATIONAL JOURNAL OF CANCER

Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state

(2015) Annelien Verfaillie et al.   Nature Communications

Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma

(2015) Aparna Jayachandran et al.   Oncotarget

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

(2014) Kotaro Ohnishi et al.   CELL

Efficacy of Vemurafenib in a Trametinib-Resistant Stage IV Melanoma Patient--Letter

(2014) M. Bernhardt et al.   CLINICAL CANCER RESEARCH

CEACAM1 Promotes Melanoma Cell Growth through Sox-2

(2014) Rona Ortenberg et al.   NEOPLASIA

Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia

(2013) S. Gandre-Babbe et al.   BLOOD

Directed Phenotype Switching as an Effective Antimelanoma Strategy

(2013) Magalí Sáez-Ayala et al.   CANCER CELL

A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma

(2013) Julie Caramel et al.   CANCER CELL

Targeting FSTL1 Prevents Tumor Bone Metastasis and Consequent Immune Dysfunction

(2013) C. Kudo-Saito et al.   CANCER RESEARCH

De- and re-differentiation of the melanocytic lineage

(2013) Lionel Larribere et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner

(2013) S. H. Stricker et al.   GENES & DEVELOPMENT

Hypoxia Contributes to Melanoma Heterogeneity by Triggering HIF1α-Dependent Phenotype Switching

(2013) Daniel S. Widmer et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hypoxia Induces Phenotypic Plasticity and Therapy Resistance in Melanoma via the Tyrosine Kinase Receptors ROR1 and ROR2

(2013) M. P. O'Connell et al.   Cancer Discovery

FSTL1 promotes bone metastasis by causing immune dysfunction

(2013) Chie Kudo-Saito   OncoImmunology

Mediators of induced pluripotency and their role in cancer cells - current scientific knowledge and future perspectives

(2012) Mathias Bernhardt et al.   Biotechnology Journal

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

(2012) Jose M. Polo et al.   CELL

Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation

(2012) Jennifer Landsberg et al.   NATURE

Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming

(2012) X Zhang et al.   ONCOGENE

Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

(2012) S M Kumar et al.   ONCOGENE

Melanoma revives an embryonic migration program to promote plasticity and invasion

(2012) Caleb M. Bailey et al.   Pigment Cell & Melanoma Research

The Epithelial-Mesenchymal Transition (EMT) Regulatory Factor SLUG (SNAI2) Is a Downstream Target of SPARC and AKT in Promoting Melanoma Cell Invasion

(2012) Nina Fenouille et al.   PLoS One

Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells

(2012) Dashayini Mahalingam et al.   Scientific Reports

Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth

(2011) G. Civenni et al.   CANCER RESEARCH

Dedifferentiation and the role of sall4 in reprogramming and patterning during amphibian limb regeneration

(2011) Anton W. Neff et al.   DEVELOPMENTAL DYNAMICS

Melanoma Spheroids Grown Under Neural Crest Cell Conditions Are Highly Plastic Migratory/Invasive Tumor Cells Endowed with Immunomodulator Function

(2011) Kiran Ramgolam et al.   PLoS One

Global epigenetic changes during somatic cell reprogramming to iPS cells

(2011) Anna Mattout et al.   Journal of Molecular Cell Biology

Generation of iPSCs from cultured human malignant cells

(2010) J. E. Carette et al.   BLOOD

Phenotypic Heterogeneity among Tumorigenic Melanoma Cells from Patients that Is Reversible and Not Hierarchically Organized

(2010) Elsa Quintana et al.   CANCER CELL

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

(2010) Ronghui Li et al.   Cell Stem Cell

Dynamic single-cell imaging of direct reprogramming reveals an early specifying event

(2010) Zachary D Smith et al.   NATURE BIOTECHNOLOGY

Intravital Imaging Reveals Transient Changes in Pigment Production and Brn2 Expression during Metastatic Melanoma Dissemination

(2009) S. Pinner et al.   CANCER RESEARCH

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells

(2009) J. Utikal et al.   JOURNAL OF CELL SCIENCE

Final Version of 2009 AJCC Melanoma Staging and Classification

(2009) Charles M. Balch et al.   JOURNAL OF CLINICAL ONCOLOGY

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

Defined factors induce reprogramming of gastrointestinal cancer cells

(2009) N. Miyoshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Melanoma-Specific Memory T Cells Are Functionally Active in Ret Transgenic Mice without Macroscopic Tumors

(2008) V. Umansky et al.   CANCER RESEARCH

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

TGFβ in Cancer

(2008) Joan Massagué   CELL

Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

(2008) Matthias Stadtfeld et al.   Cell Stem Cell

Cell motility through plasma membrane blebbing

(2008) Oliver T. Fackler et al.   JOURNAL OF CELL BIOLOGY

Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

(2008) Cesar A. Sommer et al.   STEM CELLS

Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

(2008) Jose Silva et al.   PLOS BIOLOGY