Factorial versus multi-arm multi-stage designs for clinical trials with multiple treatments

Clinical development success rates for investigational drugs

(2014) Michael Hay et al.   NATURE BIOTECHNOLOGY

Flexible sequential designs for multi-arm clinical trials

(2014) D. Magirr et al.   STATISTICS IN MEDICINE

Manual therapy, exercise therapy, or both, in addition to usual care, for osteoarthritis of the hip or knee: a randomized controlled trial. 1: clinical effectiveness

(2013) J.H. Abbott et al.   OSTEOARTHRITIS AND CARTILAGE

A generalized Dunnett test for multi-arm multi-stage clinical studies with treatment selection

(2012) D. Magirr et al.   BIOMETRIKA

A decade of change

(2012) John Arrowsmith   NATURE REVIEWS DRUG DISCOVERY

Some recommendations for multi-arm multi-stage trials

(2012) James Wason et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments

(2012) T. Jaki et al.   STATISTICS IN MEDICINE

Optimal design of multi-arm multi-stage trials

(2012) James M. S. Wason et al.   STATISTICS IN MEDICINE

Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

(2011) Patrick Royston et al.   Trials

Speeding up the Evaluation of New Agents in Cancer

(2008) M. K. B. Parmar et al.   JNCI-Journal of the National Cancer Institute