Article
Clinical Neurology
Roberto J. Perez-Roman, Evan M. Luther, David McCarthy, Julian G. Lugo-Pico, Roberto Leon-Correa, Steven Vanni, Michael Y. Wang
Summary: ACDF is the most common surgery in the cervical spine, often leading to postoperative dysphagia. A significant increase in annual dysphagia rates was observed from 2004-2014. Risk factors such as frailty, intraoperative neuromonitoring, and multiple fusion levels were identified as predictors of dysphagia.
Article
Endocrinology & Metabolism
Jinhui Shi, Xuesong Zhu, Huilin Yang, Weimin Jiang
Summary: This study compared the use of low-dose rhBMP-2 and iliac crest autographs in ACDF and investigated whether rhBMP-2 can reduce the incidence and severity of local complications. The results showed that adverse events associated with low-dose rhBMP-2 for one-and two-level ACDF are rare. It is recommended to place the rhBMP-2 carrier in the center of the interbody fusion cage and cover it bilaterally with excised local osteophytes.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Clinical Neurology
Conor N. O'Neill, Zakk J. Walterscheid, Jonathan J. Carmouche
Summary: This study described a novel grafting technique for anterior cervical discectomy and fusion (ACDF) and evaluated its clinical efficacy through a case series. The results showed that this technique effectively reduced pain symptoms in patients and achieved a high fusion rate without significant complications.
GLOBAL SPINE JOURNAL
(2022)
Article
Clinical Neurology
Roberto J. Perez-Roman, David McCarthy, Evan M. Luther, Julian G. Lugo-Pico, Roberto Leon-Correa, Wendy Gaztanaga, Karthik Madhavan, Steven Vanni
Summary: The incidence of obesity among patients undergoing ACDF is increasing, and obese patients have a higher likelihood of developing various complications during hospitalization.
Article
Multidisciplinary Sciences
Eugene J. Park, Seungho Chung, Woo-Kie Min
Summary: The study found that ACDF can increase the recovery of cervical lordosis postoperatively, leading to reciprocal changes in occipitocervical parameters.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Sarah Nguyen, Brandon A. Sherrod, Taylor M. Paziuk, Jeffrey A. Rihn, Alpesh A. Patel, Darrel S. Brodke, Erica F. Bisson
Summary: This study aimed to evaluate the incidence and predictors of postoperative dysphagia in patients undergoing anterior cervical discectomy and fusion (ACDF). The results showed that dysphagia is common immediately after ACDF, but rates of prolonged dysphagia are similar to preoperative baseline rates. Longer operation time, higher baseline dysphagia rates, and smoking status were associated with the development of short- and long-term postoperative dysphagia.
Article
Clinical Neurology
Morgan Hardman, Archis R. Bhandarkar, Ryan M. Jarrah, Mohamad Bydon
Summary: This study utilized a large national database to analyze the predictors of respiratory and pulmonary complications (RPC) following anterior cervical discectomy and fusion (ACDF). The results showed that older age, African American ethnicity, obesity, diabetes, hypertension, receiving surgery at urban hospitals, and undergoing multilevel procedures were associated with a higher likelihood of experiencing RPC. These predictors can be used to guide preoperative patient optimization.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2022)
Article
Clinical Neurology
Ashwin Veeramani, Andrew S. Zhang, Amy Z. Blackburn, Christine M. Etzel, Kevin J. DiSilvestro, Christopher L. McDonald, Alan H. Daniels
Summary: This study used machine learning algorithms and multivariate regression analysis to successfully predict risk factors for unplanned intubation following anterior cervical discectomy and fusion (ACDF) surgery. The findings can help identify high-risk patients and modify treatment plans to prevent respiratory complications and unplanned re-intubation.
GLOBAL SPINE JOURNAL
(2023)
Article
Clinical Neurology
Christopher Huang, Ralph Mobbs, Michael Selby, Kevin Phan, Prashanth Rao
Summary: This study aimed to assess the rate of adjacent-level ossification development (ALOD) in patients undergoing anterior cervical discectomy and fusion (ACDF) with and without plate. Results showed a significant association between the use of plate and ALOD, as well as a significant association between plate-to-disc distance <5 mm and ALOD.
GLOBAL SPINE JOURNAL
(2021)
Article
Clinical Neurology
Patawut Bovonratwet, Milan Kapadia, Aaron Z. Chen, Avani S. Vaishnav, Junho Song, Evan D. Sheha, Todd J. Albert, Catherine H. Gang, Sheeraz A. Qureshi
Summary: This retrospective cohort study compared the filling rate, amount, and type of opioid prescriptions following ambulatory and inpatient single-level ACDF. The study found a slightly higher filling rate for opioid prescriptions after ambulatory ACDF compared to inpatient procedures, but no significant differences in prescription amount and type. There was no association between surgical setting and persistent opioid use. These findings are important for patient counseling and support the safety of ambulatory ACDF.
Article
Surgery
Keyvan Eghbal, Iman Ahrari, Fazlollah Kamrani, Somayeh Mohamamdi, Arash Saffarian, Mohamad Jamali, Abbas Rakhsha, Reza Taheri, Abdolkarim Rahmanian, Meisam Eqbal
Summary: This study compared the outcomes of anterior cervical discectomy and fusion (ACDF) with cage alone and with plate fixation in multilevel discectomy. The results showed that plate fixation surgery had a longer duration without significant benefits, while the stand-alone cage approach could be a preferable treatment option.
ASIAN JOURNAL OF SURGERY
(2023)
Article
Biotechnology & Applied Microbiology
Yi-Wei Shen, Yi Yang, Hao Liu, Yue Qiu, Ming Li, Li-Tai Ma, Fang-Ji Gan
Summary: This study aimed to investigate the biomechanical changes during the fusion process after ACDF and explore the feasibility of reflecting the fusion status through the load changes borne by the interbody fusion cage. Finite element models representing different fusion stages were constructed based on CT scans of patients who underwent ACDF. The results showed that the facet contact force at the fusion level significantly reduced as fusion proceeded, while the intradiscal pressure and facet contact force of adjacent levels changed slightly. The stress on the surfaces of cervical instrumentation remarkably decreased after 3 to 6 months follow-up, and the stress distribution became more uniform after solid intervertebral fusion formed. The stress distribution in extension altered significantly in different fusion statuses.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Clinical Neurology
Brandon K. Couch, Richard A. Wawrose, Clarissa M. LeVasseur, Samuel W. Pitcairn, Jeremy D. Shaw, William F. Donaldson, Joon Y. Lee, William J. Anderst
Summary: This study aimed to investigate the effect of graft type on residual motion and patient-reported outcomes following anterior cervical discectomy and fusion. Results showed that allograft may result in slightly more residual motion but does not significantly affect patient-reported outcomes. Smokers who received allograft reported worse outcomes compared to nonsmokers who received allograft and smokers who received autograft.
Article
Veterinary Sciences
Cheng-Shu Chung, Lee-Shuan Lin, Yi-Min Teo
Summary: This case report describes a successful final revision surgery using locking plate fixation, rib bone and iliac crest autografts, and rhBMP-2 in a 5-year-old Bengal cat with a non-healing femoral fracture. Postoperatively, bone healing was noted 2 months after surgery and continued for 12 months, with good ambulatory function and quality of life observed in the cat despite mild lameness.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Clinical Neurology
William H. Shuman, Sean N. Neifert, Jonathan S. Gal, Daniel J. Snyder, Brian C. Deutsch, Jeffrey H. Zimering, Robert J. Rothrock, John M. Caridi
Summary: Diabetic patients undergoing ACDF have similar complication, reoperation, and readmission rates, as well as similar cost of care compared to nondiabetic patients. Diabetic patients were more likely to suffer from sepsis and bleeding complications, and had longer length of stay.
GLOBAL SPINE JOURNAL
(2022)