Journal
SLEEP MEDICINE REVIEWS
Volume 26, Issue -, Pages 33-42Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.smrv.2015.05.007
Keywords
Amyotrophic lateral sclerosis; Sleep; Respiratory; Ventilation
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Funding
- National Health and Medical Research Council of Australia (NHMRC) program grant [1037746]
- Australian Research Council Centre of Excellence in Cognition and its Disorders Memory Node [CE110001021]
- NHMRC [1003139]
- NeuroSleep NHMRC Centre of Research Excellence Grant [1060992]
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Sleep disorders in amyotrophic lateral sclerosis (ALS) present a significant challenge to the management of patients. Issues include the maintenance of adequate ventilatory status through techniques such as non-invasive ventilation, which has the ability to modulate survival and improve patient quality of life. Here, a multidisciplinary approach to the management of these disorders is reviewed, from concepts about the underlying neurobiological basis, through to current management approaches and future directions for research. (C) 2015 Elsevier Ltd. All rights reserved.
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