Sex Reversal in Non-Human Placental Mammals

Two genes substitute for the mouse Y chromosome for spermatogenesis and reproduction

(2016) Y. Yamauchi et al.   SCIENCE

A Rare Case of Testicular Disorder of Sex Development in a Dog (78,XX; SRY-Negative) with Male External Genitalia and Detection of Copy Number Variation in the Region Upstream of the SOX9 Gene

(2016) Izabela Szczerbal et al.   Sexual Development

Masculinised Behaviour of XY Females in a Mammal with Naturally Occurring Sex Reversal

(2016) Paul A. Saunders et al.   Scientific Reports

Refining the regulatory region upstream ofSOX9associated with 46,XX testicular disorders of Sex Development (DSD)

(2015) Capucine Hyon et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Polymorphism of the CTNNB1 and FOXL2 Genes is not Associated with Canine XX Testicular/Ovotesticular Disorder of Sex Development

(2015) Sylwia Salamon et al.   FOLIA BIOLOGICA-KRAKOW

Bilateral Ovotestes in a 78, XXSRY-Negative Beagle Dog

(2015) José F. Pérez-Gutiérrez et al.   JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION

Porcine SOX9 Gene Expression Is Influenced by an 18bp Indel in the 5’-Untranslated Region

(2015) Bertram Brenig et al.   PLoS One

A Revised Genome Assembly of the Region 5′ to Canine SOX9 Includes the RevSex Orthologous Region

(2015) Elena Rossi et al.   Sexual Development

Copy number variation in the region harboring SOX9 gene in dogs with testicular/ovotesticular disorder of sex development (78,XX; SRY-negative)

(2015) Malgorzata Marcinkowska-Swojak et al.   Scientific Reports

Sex reversal syndrome in the horse: Four new cases of feminization in individuals carrying a 64,XY SRY negative chromosomal complement

(2014) Gabriel Anaya et al.   ANIMAL REPRODUCTION SCIENCE

High-Throughput Sequencing Analyses of XX Genital Ridges Lacking FOXL2 Reveal DMRT1 Up-Regulation Before SOX9 Expression During the Sex-Reversal Process in Goats1

(2014) Maëva Elzaiat et al.   BIOLOGY OF REPRODUCTION

FOXL2 Is a Female Sex-Determining Gene in the Goat

(2014) Laurent Boulanger et al.   CURRENT BIOLOGY

Testis development in the absence of SRY: chromosomal rearrangements at SOX9 and SOX3

(2014) Annalisa Vetro et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

XY FEMALES DO BETTER THAN THE XX IN THE AFRICAN PYGMY MOUSE,MUS MINUTOIDES

(2014) Paul A. Saunders et al.   EVOLUTION

Sox9 Duplications Are a Relevant Cause of Sry-Negative XX Sex Reversal Dogs

(2014) Elena Rossi et al.   PLoS One

First Description of Scrotal Testicles in a Dog Affected by 78, XX Testicular Disorder of Sex Development

(2014) AP Del Carro et al.   REPRODUCTION IN DOMESTIC ANIMALS

Zytogenetische und molekulargenetische Abklärungen bei einem Pferd mit SRY-negativer Sex-Umkehr

(2014) A. Pieńkowska-Schelling et al.   SCHWEIZER ARCHIV FUR TIERHEILKUNDE

Hormone-Independent Pathways of Sexual Differentiation

(2014) Marilyn B. Renfree et al.   Sexual Development

Anatomical and Molecular Analyses of XY Ovaries from the African Pygmy MouseMus minutoides

(2014) Massilva Rahmoun et al.   Sexual Development

Polygenic sex determination

(2013) Emily C. Moore et al.   CURRENT BIOLOGY

Cell-autonomous sex determination outside of the gonad

(2013) Arthur P. Arnold et al.   DEVELOPMENTAL DYNAMICS

SOX9 Duplication Linked to Intersex in Deer

(2013) Regina Kropatsch et al.   PLoS One

A Genome-Wide Association Study Points out the Causal Implication of SOX9 in the Sex-Reversal Phenotype in XX Pigs

(2013) Sarah Rousseau et al.   PLoS One

Two Y Genes Can Replace the Entire Y Chromosome for Assisted Reproduction in the Mouse

(2013) Yasuhiro Yamauchi et al.   SCIENCE

Insights into the Evolutionary History of the X-Linked Sex Reversal Mutation in Mus minutoides: Clues from Sequence Analyses of the Y-Linked Sry Gene

(2013) F. Veyrunes et al.   Sexual Development

Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes

(2012) Krishanu Mukherjee et al.   BMC EVOLUTIONARY BIOLOGY

Sox9 gene regulation and the loss of the XY/XX sex-determining mechanism in the mole vole Ellobius lutescens

(2012) Stefan Bagheri-Fam et al.   CHROMOSOME RESEARCH

SRY-positive 78, XY ovotesticular disorder of sex development in a wolf cloned by nuclear transfer

(2012) Jung Taek Kang et al.   Journal of Veterinary Science

The Presence of the Y-Chromosome, Not the Absence of the Second X-Chromosome, Alters the mRNA Levels Stored in the Fully Grown XY Mouse Oocyte

(2012) Baozeng Xu et al.   PLoS One

The Molecular Genetics of Sex Determination and Sex Reversal in Mammals

(2012) Alexander Quinn et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Natural Exceptions to Normal Gonad Development in Mammals

(2012) R. Jiménez et al.   Sexual Development

Escape from X inactivation in mice and humans

(2012) Joel B Berletch et al.   GENOME BIOLOGY

The molecular and cellular basis of gonadal sex reversal in mice and humans

(2012) Nick Warr et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Additional copies of CBX2 in the genomes of males of mammals lacking SRY, the Amami spiny rat (Tokudaia osimensis) and the Tokunoshima spiny rat (Tokudaia tokunoshimensis)

(2011) Asato Kuroiwa et al.   CHROMOSOME RESEARCH

XY Sox9 embryonic loss-of-function mouse mutants show complete sex reversal and produce partially fertile XY oocytes

(2011) Rowena Lavery et al.   DEVELOPMENTAL BIOLOGY

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

78,XX Testicular DSD Syndrome in a Mongrel Dog

(2011) A Max et al.   REPRODUCTION IN DOMESTIC ANIMALS

XX SRY-Negative True Hermaphrodism in Two Dogs: Clinical, Morphological, Genetic and Cytogenetic Studies

(2011) D. Groppetti et al.   Sexual Development

Robertsonian Translocation in a Sex Reversal Dog (XX, SRY negative) May Indicate that the Causative Mutation for This Intersexuality Syndrome Resides on Canine Chromosome 23 (CFA23)

(2011) M. Switonski et al.   Sexual Development

Equine Disorders of Sexual Development in 17 Mares Including XX, SRY-Negative, XY, SRY-Negative and XY, SRY-Positive Genotypes

(2011) D.A.F. Villagómez et al.   Sexual Development

Telling the Story of XX Sex Reversal in the Goat: Highlighting the Sex-Crossroad in Domestic Mammals

(2011) M. Pannetier et al.   Sexual Development

Disorders of Sexual Development and Abnormal Early Development in Domestic Food-Producing Mammals: The Role of Chromosome Abnormalities, Environment and Stress Factors

(2011) L.A. Favetta et al.   Sexual Development

Molecular and Cytogenetic Studies in a Case of XX SRY-Negative Sex Reversal in an Arabian Horse

(2011) F. Ciotola et al.   Sexual Development

Gonadal and Sex Differentiation Abnormalities of Dogs and Cats

(2011) V.N. Meyers-Wallen   Sexual Development

Genetic analysis of 38XX males with genital ambiguities and true hermaphrodites in pigs

(2010) E. Pailhoux et al.   ANIMAL GENETICS

Molecular heterogeneity of XY sex reversal in horses

(2010) T. Raudsepp et al.   ANIMAL GENETICS

The process of a Y-loss event in an XO/XO mammal, the Ryukyu spiny rat

(2010) Asato Kuroiwa et al.   CHROMOSOMA

A Case of Ovine Female XY Sex Reversal Syndrome Not Related to Anomalies in the Sex-Determining Region Y (SRY)

(2010) L.M. Ferrer et al.   CYTOGENETIC AND GENOME RESEARCH

A study of goat SRY protein expression suggests putative new roles for this gene in the developing testis of a species with long-lasting SRY expression

(2010) Fatemeh Montazer-Torbati et al.   DEVELOPMENTAL DYNAMICS

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Chimpanzee and human Y chromosomes are remarkably divergent in structure and gene content

(2010) Jennifer F. Hughes et al.   NATURE

A Case of SRY-Positive 38,XY True Hermaphroditism (XY Sex Reversal) in a Cat

(2010) D. H. Schlafer et al.   VETERINARY PATHOLOGY

Ovaries and Female Phenotype in a Girl with 46,XY Karyotype and Mutations in the CBX2 Gene

(2009) Anna Biason-Lauber et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Classical and Molecular Cytogenetics of Disorders of Sex Development in Domestic Animals

(2009) D.A.F. Villagómez et al.   CYTOGENETIC AND GENOME RESEARCH

64,XX, SRY-, and ZFY-Negative Icelandic Horse Likely to Be True Hermaphrodite

(2009) Sigridur K. Bodvarsdottir et al.   JOURNAL OF EQUINE VETERINARY SCIENCE

SOX9 is not required for the cellular events of testicular organogenesis in XX mole ovotestes

(2009) F. David Carmona et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

A novel sex determination system in a close relative of the house mouse

(2009) F. Veyrunes et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Disease-Causing 7.4 kb Cis-Regulatory Deletion Disrupting Conserved Non-Coding Sequences and Their Interaction with the FOXL2 Promotor: Implications for Mutation Screening

(2009) Barbara D'haene et al.   PLoS Genetics

Sry-negative XX true hermaphroditism in a roe deer

(2008) G. Pajares et al.   ANIMAL REPRODUCTION SCIENCE

Disorders of sex development: a new definition and classification

(2008) Ieuan A. Hughes   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Cytogenetic screening of livestock populations in Europe: an overview

(2008) A. Ducos et al.   CYTOGENETIC AND GENOME RESEARCH

Sex chromosome abnormalities and sterility in river buffalo

(2008) G.P. Di Meo et al.   CYTOGENETIC AND GENOME RESEARCH

Chromosomal aspects and inheritance of the XY female condition in Akodon azarae (Rodentia, Sigmodontinae)

(2008) María I. Ortiz et al.   MAMMALIAN BIOLOGY

Sex determination of Microtus mandarinus mandarinus is independent of Sry gene

(2008) Yanqiu Chen et al.   MAMMALIAN GENOME

Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer

(2008) Ryohei Sekido et al.   NATURE

Highly effective SNP-based association mapping and management of recessive defects in livestock

(2008) Carole Charlier et al.   NATURE GENETICS

The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.YTIR sex-reversed mouse ovary

(2008) Michelle Alton et al.   REPRODUCTION

Mutations in the RSPO1 Coding Region Are Not the Main Cause of Canine SRY-Negative XX Sex Reversal in Several Breeds

(2008) L. De Lorenzi et al.   Sexual Development

Attempt to Rescue Sex-Reversal by Transgenic Expression of the PISRT1 Gene in XX PIS–/– Goats

(2008) L. Boulanger et al.   Sexual Development

XX/XY Chimerism in Cattle: Clinical and Cytogenetic Studies

(2008) V. Peretti et al.   Sexual Development

Cloning endangered gray wolves (Canis lupus) from somatic cells collected postmortem

(2008) H.J. Oh et al.   THERIOGENOLOGY

X chromosome detection in an XO mare using a human X paint probe, and PCR detection of SRY and amelogenin genes in 3 XY mares

(2007) A. MÄKINEN et al.   EQUINE VETERINARY JOURNAL

The evolution of female mole ovotestes evidences high plasticity of mammalian gonad development

(2007) F. David Carmona et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION