Article
Medicine, General & Internal
Yannick Bejot, Anne-Laure Soilly, Marc Bardou, Gauthier Duloquin, Thibaut Pommier, Gabriel Laurent, Yves Cottin, Lucie Vadot, Heloise Adam, Mathieu Boulin, Maurice Giroud
Summary: This article describes a protocol for a randomized clinical trial that aims to evaluate the efficiency and effectiveness of an intensive multidisciplinary follow-up of patients compared with standard care. The study involves patients suffering from stroke, transient ischemic attack (TIA), or myocardial infarction (MI). The trial will collect various outcomes to assess the cost-utility and effectiveness of the two follow-up strategies.
Article
Peripheral Vascular Disease
Yan-Feng Zhou, Simiao Chen, Guodong Wang, Shuohua Chen, Yan-Bo Zhang, Jun-Xiang Chen, Zhou-Zheng Tu, Gang Liu, Shouling Wu, An Pan
Summary: The workplace-based hypertension management program effectively reduced blood pressure levels, lowered the risks of major adverse cardiovascular events, and decreased all-cause mortality in Chinese men with hypertension, according to the study.
Article
Multidisciplinary Sciences
Nicolas Girerd, John Cleland, Stefan D. Anker, William Byra, Carolyn S. P. Lam, David Lapolice, Mandeep R. Mehra, Dirk J. van Veldhuisen, Emmanuel Bresso, Zohra Lamiral, Barry Greenberg, Faiez Zannad
Summary: This study evaluated the associations between clinical events and proteomic biomarkers in patients with HF and CAD. The results showed that biomarkers associated with inflammation and remodeling mechanisms were strong predictors of various cardiovascular events.
SCIENTIFIC REPORTS
(2022)
Letter
Medicine, General & Internal
Marie-Joelle Jabagi, Marion Bertrand, Jeremie Botton, Stephane Le Vu, Alain Weill, Rosemary Dray-Spira, Mahmoud Zureik
Summary: In this French study, recipients of the bivalent vaccine and the original monovalent vaccine had similar risk of cardiovascular events 21 days after vaccination.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Peter Lee, Angela L. Brennan, Dion Stub, Diem T. Dinh, Jeffrey Lefkovits, Christopher M. Reid, Ella Zomer, Danny Liew
Summary: The study aimed to determine the minimum level of clinical benefit required for the Victorian Cardiac Outcomes Registry (VCOR) to be cost-effective. A cost-effectiveness model was constructed to compare observed deaths and costs with and without VCOR. The findings suggest that VCOR is likely cost-effective and provides value to the Victorian healthcare system.
Article
Medicine, General & Internal
Yue Hu, Qihui Chen, Bo Zhang
Summary: This study examines the impact of chronic disease diagnoses on alcohol consumption behavior among elderly Chinese individuals. The findings suggest that being diagnosed with chronic diseases leads to a reduction in weekly consumption of beer, red wine, and Chinese spirits, as well as overall alcohol intake. Additionally, certain demographic factors such as gender, location, smoking habits, and social environment play a role in how individuals respond to chronic disease diagnoses.
Article
Cardiac & Cardiovascular Systems
Zhe Liang, Qi Chen, Fei Yang, Xianliang Yan, Xuehui Zhang, Xue Chen, Fang Fang, Quanming Zhao
Summary: In China, treatment with evolocumab for myocardial infarction patients was not cost-effective based on the 2019 pricing; however, it was more favorable in myocardial infarction patients with familial hypercholesterolemia (FH).
CARDIOVASCULAR DRUGS AND THERAPY
(2021)
Article
Public, Environmental & Occupational Health
Edwine Barasa, Jacob Kazungu, Peter Nguhiu, Nirmala Ravishankar
Summary: Low/middle-income countries in sub-Saharan Africa are increasingly turning to public contributory health insurance to remove financial barriers and extend financial risk protection. Health insurance coverage in the region is low and pro-rich, with only four countries having coverage levels above 20% supported by tax funding. Media exposure, socioeconomic status, and level of education make significant contributions to the inequality in health insurance coverage.
Article
Public, Environmental & Occupational Health
Rosella Ciurleo, Maria Cristina De Cola, Nera Agabiti, Mirko Di Martino, Placido Bramanti, Francesco Corallo
Summary: Audit and feedback (A & F) strategies are used to monitor and improve clinical guidelines in evidence-based medicine. The EASY-NET project in Italy aims to evaluate the effectiveness of A & F strategies in improving healthcare practice and equity in various clinical and organizational settings. This study focuses on the effectiveness of A & F strategies in the settings of acute myocardial infarction (AMI) and ischemic stroke, covering both acute and rehabilitation care processes.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Chemistry, Multidisciplinary
Fitri Fareez Ramli, Adli Ali, Nurul 'Izzah Ibrahim
Summary: Tocotrienols have shown significant benefits in cerebral and myocardial I/R injury, improving structural, functional, and biochemical parameters while reducing oxidative stress, inflammation, and apoptosis. Differences in animal models, disease inductions, tocotrienol forms, and bias risks were limitations in the analysis, but tocotrienols have the potential to serve as a supplement for reducing the impact of reperfusion injury.
APPLIED SCIENCES-BASEL
(2021)
Review
Cardiac & Cardiovascular Systems
James Nadel, Andrew Jabbour, Roland Stocker
Summary: Intracellular myeloperoxidase (MPO) plays a role in innate immunity, but when released extracellularly during inflammation, it causes oxidative tissue damage. Recent research has found that extracellular MPO is abundant in unstable atheroma and is causally linked to plaque destabilization. By separating the protective and harmful effects of MPO, it can be selectively detected and targeted using non-invasive molecular imaging and pharmacotherapies. MPO is a potentially superior inflammatory target compared to other therapies and imaging biomarkers, making it useful in the management of patients with vulnerable atherosclerotic plaques.
CARDIOVASCULAR RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Brady Hooley, Doris Osei Afriyie, Gunther Fink, Fabrizio Tediosi
Summary: This study found that low- and middle-income countries have low levels of health insurance coverage, and health insurance may not necessarily reduce household health expenditure. However, the lack of regular estimates of health insurance coverage in these countries limits the ability to draw solid conclusions.
Article
Multidisciplinary Sciences
Tae-Min Rhee, Hyung-Kwan Kim, Bong-Seong Kim, Kyung-Do Han, Hyun-Jung Lee, In-Chang Hwang, Heesun Lee, Jun-Bean Park, Yeonyee E. Yoon, Yong-Jin Kim, Goo-Yeong Cho
Summary: Limited data are available on the long-term outcomes in HCM patients with significant CAD requiring revascularization. This study showed that HCM patients who underwent coronary revascularization had a significantly higher risk of cardiovascular death, SCD, ischemic stroke, and heart failure compared to the non-HCM control group.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
Lamiae Grimaldi-Bensouda, Bernard Begaud, Jacques Benichou, Clementine Nordon, Olivia Dialla, Nicolas Morisot, Yann Hamon, Yves Cottin, Elie Serrano, Lucien Abenhaim, Emmanuel Touze
Summary: The study aimed to assess the risk of stroke and myocardial infarction associated with decongestant use, but found no increased risk in patients 70 years of age and younger without a history of prior stroke or MI. The research conducted a nested case-crossover study in France and used conditional logistic multivariable models to estimate odds ratios, ultimately concluding that decongestant use did not correlate with a higher risk of stroke or MI.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Shih-Chuan Chou, Arthur S. Hong, Scott G. Weiner, J. Frank Wharam
Summary: This study found that switching from low-deductible health plans to high-deductible plans mandated by employers was associated with decreased ED visits and hospitalization for nonspecific chest pain, but did not significantly affect post-ED cardiac testing. However, enrollment in high-deductible plans was linked to an increase in 30-day acute myocardial infarction admissions after ED diagnosis of nonspecific chest pain, especially among members from higher-poverty neighborhoods.
Article
Economics
Amelia M. Haviland, Matthew D. Eisenberg, Ateev Mehrotra, Peter J. Huckfeldt, Neeraj Sood
JOURNAL OF HEALTH ECONOMICS
(2016)
Article
Medicine, General & Internal
Neeraj Sood, Allen P. Ugargol, Kayleigh Barnes, Anish Mahajan
Article
Medicine, General & Internal
Neeraj Sood, Zachary Wagner
Letter
Medicine, General & Internal
Anna D. Sinaiko, Ateev Mehrotra, Neeraj Sood
JAMA INTERNAL MEDICINE
(2016)
Article
Health Care Sciences & Services
Xinke Zhang, Amelia Haviland, Ateev Mehrotra, Peter Huckfeldt, Zachary Wagner, Neeraj Sood
HEALTH SERVICES RESEARCH
(2018)
Article
Health Care Sciences & Services
Peter J. Huckfeldt, Lianna Weissblum, Jose J. Escarce, Pinar Karaca-Mandic, Neeraj Sood
HEALTH SERVICES RESEARCH
(2018)
Article
Rehabilitation
Lianna Weissblum, Peter Huckfeldt, Jose Escarce, Pinar Karaca-Mandic, Neeraj Sood
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2019)
Article
Orthopedics
Neeraj Sood, Victoria L. Shier, Haley Nakata, Richard Iorio, Jay R. Lieberman
JOURNAL OF ARTHROPLASTY
(2019)
Article
Health Care Sciences & Services
Peter J. Huckfeldt, Jing Gu, Jose J. Escarce, Pinar Karaca-Mandic, Neeraj Sood
Summary: Vertically integrated hospital and SNF care was associated with shorter hospital and SNF stays. However, there were few beneficial associations with other outcomes, suggesting limited coordination benefits from vertical integration.
HEALTH SERVICES RESEARCH
(2021)
Article
Health Care Sciences & Services
Neeraj Sood, Victoria Shier, Peter J. Huckfeldt, Lianna Weissblum, Jose J. Escarce
Summary: The study indicates that receiving vertically integrated care in hospital-based IRFs shortens institutional length of stay, reduces readmission rates, increases the likelihood of being discharged to home care, without worse patient clinical outcomes. However, there were little differences in health care use or patient outcomes between patients discharged from a parent hospital compared to patients from other hospitals in freestanding IRFs.
HEALTH SERVICES RESEARCH
(2021)
Article
Multidisciplinary Sciences
Neeraj Sood, Rashmi Shetgiri, Anna Rodriguez, Dianna Jimenez, Sonia Treminino, Amanda Daflos, Paul Simon
Summary: Rapid antigen testing shows promise in identifying COVID infections in children, especially those with symptoms, and is negatively associated with Ct values.
Article
Health Care Sciences & Services
Christopher Whaley, Neeraj Sood, Michael Chernew, Leanne Metcalfe, Ateev Mehrotra
Summary: The introduction of a rewards program for receiving care from lower-priced providers led to modest price reductions, with the most savings concentrated in MRI services. Participations rates in the program were highest for MRI services, with 30% of patients engaging with the program in the first year, and 7.8% receiving an incentive payment in the second year.
HEALTH SERVICES RESEARCH
(2022)
Article
Medicine, General & Internal
Jason N. Doctor, Anders H. Berg, Tara K. Knight, Mika Kadono, Emily Stewart, Rajan Sonik, Michael Hochman, Neeraj Sood
Summary: This study aimed to measure the impact of SARS-CoV-2 on an underserved Hispanic population in Los Angeles and identify factors associated with paediatric seropositivity. The researchers conducted a cross-sectional study at a Federally Qualified Health Center in Los Angeles called AltaMed, inviting a random sample of households who had received healthcare there. They analyzed data from 390 adults and 332 paediatric participants from 196 households and found that the seropositivity rates were 52.11% for paediatric participants and 63.58% for adults. Factors associated with paediatric seropositivity included type 2 diabetes in a household member, receipt of food stamps, and lower head-of-household education. The findings highlight the high level of SARS-CoV-2 seropositivity among Hispanic children and adolescents in Los Angeles and suggest that these factors should be considered when making COVID-19 mitigation recommendations for paediatricians.
Article
Medicine, Research & Experimental
Natalie E. Leland, Victoria Shier, Catherine Verrier Piersol, Cara Lekovitch, Jenny Martinez, Yuna H. Bae-Shaaw, Neeraj Sood, Claire Day, Paul Cass, Dominique Como, Carin Wong, Felicia Chew
Summary: This study aims to compare team-based and problem-based approaches to non-pharmacological care for Alzheimer's Disease and Related Dementias (ADRD) in nursing homes. It will evaluate the effectiveness of these approaches on long-term resident outcomes and explore their potential protective effects against COVID-19. This research is significant for optimizing staff training and improving ADRD care delivery.
CONTEMPORARY CLINICAL TRIALS COMMUNICATIONS
(2023)
Article
Health Care Sciences & Services
Christopher Stomberg, Margaret Albaugh, Saul Shiffman, Neeraj Sood
AMERICAN JOURNAL OF MANAGED CARE
(2016)